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Clinical Trial Summary

This study will examine the utility of chitosan for reduction of blood or tissue levels of AGEs in patients with prostate cancer who are clinically stable on androgen-deprivation therapy.


Clinical Trial Description

The overall goal of this study is to identify a safe dose of the metabolic supplement, Chitosan that can help reduce AGE (advanced glycation endproducts) levels in patients with prostate cancer. Chitosan is a naturally occurring substance found in shellfish. This study will be using Chitosan prepared from the shells of cold-water shrimp. Chitosan is approved by the FDA for use in wound dressings and has been used in published clinical trials for weight loss but is not approved for the purposes of this study. AGEs are a type of metabolite, or substance, found in food and produced in the body. The researchers helping conduct this study have found a potential link between AGE levels and cancer. Participation in this study will require three study visits over the course of about 3 months. During these visits subjects will be asked to provide blood and stool samples as well as complete surveys about their quality of life. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03712371
Study type Interventional
Source Medical University of South Carolina
Contact Alan Brisendine
Phone 843-792-9007
Email hcc-clinical-trials@musc.edu
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date December 1, 2018
Completion date December 1, 2021

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