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NCT ID: NCT03718338 Terminated - Clinical trials for Prostate Adenocarcinoma

Mechanisms of Metabolic and Hormone Action on Plaque Formation in Brain and Carotid Vessels in Patients With Prostate Adenocarcinoma

Start date: October 8, 2019
Phase:
Study type: Observational

This trial studies the mechanisms of metabolic and hormone action on plaque formation in brain and carotid vessels in patients with prostate adenocarcinoma. Studying the biomarkers in the laboratory may help doctors know the impact of androgen deprivation on metabolic, brain and cardiovascular endpoints.

NCT ID: NCT03718143 Terminated - Clinical trials for Acute Myeloid Leukemia

AZD1775 in Advanced Acute Myeloid Leukemia, Myelodysplastic Syndrome and Myelofibrosis

Start date: May 8, 2019
Phase: Phase 2
Study type: Interventional

A phase II study testing the efficacy of combined AZD1775 with AraC or single agent activity of AZD1775 in three arms: Arm A has subjects age 60 years or older who are newly diagnosed with AML receiving the combination of the drugs; Arm B has subjects who are have relapsed/refractory AML and HMA failure MDS patients being allocated to either the combination Arm B or single agent AZD1775 Arm C.

NCT ID: NCT03717532 Terminated - Clinical trials for Patellofemoral Pain Syndrome

Blood Flow Restriction Therapy in Patellofemoral Pain Syndrome

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the efficacy of blood restriction therapy by comparing increase in muscle mass and strength in patients that receive blood restriction therapy to patients who receive a placebo.

NCT ID: NCT03717480 Terminated - Clinical trials for Hematologic Malignancy

Ex Vivo TCR αβ T Cell Depletion for Graft-Versus-Host Disease Prophylaxis in Mismatched Donor Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies

Start date: January 21, 2020
Phase: Phase 2
Study type: Interventional

This research study is studying the removal of a subset of white blood cells (called alpha/beta T cells) from the donor product using a cell separation device before the product is transplanted into the participant. The device used to remove the α/βT cells in this study is: -CliniMACS® TCR α/β Reagent System

NCT ID: NCT03717012 Terminated - Clinical trials for Idiopathic Pulmonary Fibrosis

Study of Pulmonary Rehabilitation in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Start date: November 15, 2018
Phase: Phase 4
Study type: Interventional

The main objectives of this study are: - Determine the difference in change from baseline in Six Minute Walk Distance (6MWD) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary fibrosis (IPF) - Determine the difference in change in Quality of Life (QoL) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary fibrosis (IPF) - Determine if there is an enduring effect in 6MWD, QoL and lung function from pulmonary rehabilitation (PR) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary fibrosis (IPF)

NCT ID: NCT03716258 Terminated - Parkinson Disease Clinical Trials

Characterizing Biomarkers of Early Parkinson's Disease Progression (TREG)

TREG
Start date: January 1, 2019
Phase:
Study type: Observational

The purpose of this study is to look at a blood marker of inflammation in early untreated Parkinson's disease.

NCT ID: NCT03716050 Terminated - Clinical trials for Perfusion; Complications

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

Start date: January 30, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized study using a variety of techniques to compare and examine blood flow to the remaining skin after mastectomy. All treatments being used are considered standard of care and are not experimental. The objective is to compare the techniques and the incidence of perfusion related problems in patient's undergoing mastectomy with immediate breast reconstruction.

NCT ID: NCT03715530 Terminated - Preterm Birth Clinical Trials

Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women

PAMG-1
Start date: September 2007
Phase: N/A
Study type: Interventional

The study is to evaluate the accuracy of a test device called "PAMG-1" to see if a pregnant women has ruptured membranes in comparison to standardly used testing methods.

NCT ID: NCT03715270 Terminated - Clinical trials for Perfusion; Complications

Evaluation of Tissue Oxygen Levels During Breast Reconstruction With a New Surgical Device

Presygen™
Start date: January 30, 2019
Phase:
Study type: Observational

This study is designed to evaluate the information provided to the clinicians by the surgical imaging device. It is also to gain insight on the user interface and how "user friendly" it is to the clinician.

NCT ID: NCT03715153 Terminated - Clinical trials for Autism Spectrum Disorder (ASD)

Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.

Start date: October 4, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacity and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.