Clinical Trials Logo

Preterm Birth clinical trials

View clinical trials related to Preterm Birth.

Filter by:

NCT ID: NCT03689166 Recruiting - Preterm Birth Clinical Trials

Effect of Probiotics on the Preterm Delivery Rate in Pregnant Women at High Risk for Preterm Birth

PROPEV
Start date: October 23, 2017
Phase: N/A
Study type: Interventional

Preterm birth (PB) continues to be the main cause of perinatal morbidity and mortality, with emotional and economic consequences. Despite improvements in health, PB prevalence remains stable, possibly due to complex causes such as maternal age, stress, multiparity, etc. Shortening of the uterine cervix in early stages of gestation is a risk factor for PB. The presence of abnormal vaginal microbiota in the early stages of pregnancy is als a risk factor for PB. However, no studies have analysed the impact of probiotics (live microorganisms which, in adequate amounts, confer a health benefit on the host) on the PB in high-risk PB patients (pregnant women with threatened preterm delivery, i.e., uterine contractions and cervical shortening, with a 30% PB risk before 34 weeks, and 50% PB prior to 37 weeks (> 6-10% PB). Similarly, the effect of probiotics on vaginal flora dominated by lactic acid-producing bacteria could be analysed.

NCT ID: NCT03673579 Recruiting - Stress Clinical Trials

Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - MHSB

Start date: June 14, 2018
Phase: N/A
Study type: Interventional

This study evaluates the use of a NICU clinical integration system (Dashboard and accessories) in improving the quality of care delivered, patient health outcomes, and parent and clinician satisfaction. Clinicians will be asked to follow their current standard of care practices with the aid of this technology. About half of participants will receive care in NICU rooms with the Dashboard installed while the other half will receive standard care without the Dashboard.

NCT ID: NCT03673566 Not yet recruiting - Stress Clinical Trials

Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - CHMCO

Start date: March 2019
Phase: N/A
Study type: Interventional

This study evaluates the use of a NICU clinical integration system (Dashboard and accessories) in improving the quality of care delivered, patient health outcomes, and parent and clinician satisfaction. Clinicians will be asked to follow their current standard of care practices with the aid of this technology. About half of participants will receive care in NICU rooms with the Dashboard installed while the other half will receive standard care without the Dashboard.

NCT ID: NCT03668860 Not yet recruiting - Preterm Birth Clinical Trials

India Dexamethasone and Betamethasone

Start date: September 2018
Phase: Phase 1
Study type: Interventional

An open label, randomized, two-period, crossover, study to compare the pharmacokinetics and pharmacodynamics of single dose Dexamethasone and Betamethasone administered orally and intramuscularly in 48 healthy, adult, female subjects under fasting conditions. This study is being conducted in Bangalore, India.

NCT ID: NCT03668327 Recruiting - Preterm Birth Clinical Trials

Preterm Birth Cohort Study in Guangzhou

PBCSG
Start date: February 1, 2012
Phase:
Study type: Observational

The Preterm Birth Cohort Study in Guangzhou (PBCSG) aims to explore the impact of genetic and environmental factors including life styles on preterm birth, to examine the interaction effect between these factors, and to follow up the short-term and long-term outcomes of preterm childrens.

NCT ID: NCT03655379 Recruiting - Preterm Birth Clinical Trials

A Novel Technique for Prediction of Preterm Birth: Fetal Breathing Patterns

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Preterm birth refers to a delivery that occurs before 37 weeks of gestation. Identification of those who will eventually deliver in the preterm period is very important. However, few interventions have been proven to prolong pregnancy in women at risk such as cervicovaginal fetal fibronectin (fFN) level or transvaginal cervical length measurements. In a meta-analysis comparing fetal breathing with cervicovaginal fetal fibronectin (fFN) level or transvaginal cervical length measurements, absence of fetal breathing was superior to other methods for prediction of preterm birth in 48 hours or 7 days. In this study, the investigators hypothesized that if a fetus holds its breath in case of preterm birth, then there may be specific fetal breathing patterns during preterm labor, which may be detected by ultrasonography

NCT ID: NCT03646578 Completed - Preterm Birth Clinical Trials

Maternal Anxiety Related to How the Pediatrician Provided Prenatal Information About Preterm Birth

Infoprema
Start date: November 1, 2014
Phase:
Study type: Observational

Women hospitalized for preterm labor require clear information about prematurity. This study assessed whether or not specific written information about prematurity delivered at admission to the unit combined with an oral explanation from a pediatrician would decrease women's anxiety compared to an oral explanation alone. This was a prospective, single-center observational study.Women were included in the high-risk pregnancies department and distributed into two groups: receiving ''only oral'' information for a prenatal clinical consultation with a senior pediatrician or receiving ''combined'' oral information + a booklet about prematurity given to the women at admission. The primary endpoint was the change in anxiety-state (before and after the information procedure) evaluated by the State Trait Anxiety Inventory-Y (STAI-Y).

NCT ID: NCT03638037 Recruiting - Clinical trials for Vitamin D Deficiency

Correlation Between Maternal Vitamin D Level And Preterm Birth

Start date: September 2, 2018
Phase:
Study type: Observational

Assessment of correlation between vitamin D level and prevalence of preterm births remains limited. The exact role of vitamin D in preterm birth has not yet been clearly defined ,where some studies showed vitamin D deficiency increased the risk of preterm birth while other studies found no correlation. In this study will try to continue research on this subject.

NCT ID: NCT03630679 Not yet recruiting - Healthy Clinical Trials

A Study Evaluating Sleep, Stress and Infant Nutrition Using a Chatbot

Start date: October 2018
Phase:
Study type: Observational

20 parents with healthy preterm infants (born at <37 weeks of gestation), age 0-6 months and discharged from the hospital at time of enrollment and 20 parents with healthy full-term infants (born at ≥37 weeks of gestation), age 0-6 months and discharged from the hospital at time of enrollment will be enrolled to obtain records of sleep, stress, and infant nutrition from parents of infants (preterm and full-term) through interaction with the study chatbot.

NCT ID: NCT03618836 Completed - Preterm Birth Clinical Trials

Study of the Risk of PREMaturité According to the Balance of Bacterial Flora VAginale

PREMEVA2
Start date: November 2011
Phase:
Study type: Observational

Objective To compare vaginal microbiota in the first trimester of pregnancy between spontaneous preterm and term deliveries