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NCT ID: NCT05616065 Completed - Education, Medical Clinical Trials

Bias Reduction in Academic Recruitment

BRIAR
Start date: October 12, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to determine if, with respect to medical students applying for residency in emergency medicine, prior knowledge of an applicant's academic record affects their ranking during their interviews. Attendings interviewing candidates will either be blinded to their prior academic records or be allowed to review them prior to the interview. The interviewer's final score of the applicant will be measured, comparing blinded versus unblinded assessors.

NCT ID: NCT05615948 Completed - Clinical trials for Major Depressive Disorder

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

Start date: December 6, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the effects of simultaneous administration of oral aspirin and oral ketamine as a therapeutic for those with Treatment Resistant Depression.

NCT ID: NCT05615922 Completed - Clinical trials for Primary Progressive Aphasia

Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA)

Start date: December 24, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to establish the feasibility of a program of remotely supervised transcranial direct current stimulation (RS-tDCS) paired with language skills practice for people living with the semantic or logopenic variants of primary progressive aphasia (PPA). There are currently no established standard-of-care treatments for PPA. This study will evaluate whether RS-tDCS combined with language skills practice is a feasible study design for individuals with PPA.

NCT ID: NCT05615805 Completed - Clinical trials for Diabetic Macular Edema

The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.

NCT ID: NCT05615467 Completed - Healthy Clinical Trials

A Study of Effect of LY3556050 on Metformin in Healthy Participants

Start date: November 15, 2022
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate how much Metformin gets into the bloodstream and how long the body takes to get rid of it when it is administered orally in combination with LY3556050 in healthy participants. Iohexol will be administered to evaluate kidney function. Each enrolled participant will remain in the study for up to 7 weeks including the screening period.

NCT ID: NCT05615298 Completed - Breast Cancer Clinical Trials

Study to Evaluate Effectiveness of Investigational Device in the Assistance of Detection and Diagnosis of Breast Cancer

Start date: June 15, 2020
Phase:
Study type: Observational

This study aims to evaluate Effectiveness of Investigational Device, Lunit INSIGHT MMG, in the assistance of Detection and Diagnosis of Breast Cancer during Screening Mammography Interpretation.

NCT ID: NCT05615012 Completed - Clinical trials for Healthy Participants

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Start date: November 11, 2022
Phase: Phase 1
Study type: Interventional

The aim of this study is to assess the effect of coadministration of multiple oral doses of BMS-986322 with rosuvastatin, metformin, and methotrexate in healthy participants.

NCT ID: NCT05614895 Completed - Clinical trials for Bacterial Infections

A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections

Start date: December 3, 2022
Phase: Phase 1
Study type: Interventional

The main aim of the study is to investigate the plasma pharmacokinetics (PK) and safety of intravenous (IV) administration of a single dose of 400 milligrams (mg) or 600 mg RO7223280 in critically ill participants with bacterial infections.

NCT ID: NCT05614726 Completed - Constipation Clinical Trials

A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study

Start date: June 18, 2021
Phase: N/A
Study type: Interventional

This randomized, placebo-controlled, double-blind study will determine the effect of daily supplementation with a probiotic blend in 60 apparently healthy men and women recruited at a single investigational center in Northeast Ohio (i.e., The Center for Applied Health Sciences). Subjects will attend three study visits. During Visit 1, subjects will be screened for participation [i.e., medical history, routine blood work, background baseline diet]. During Visits 2 and 3 subjects will complete questionnaires that assess their gastrointestinal health (e.g., abdominal discomfort/bloating, constipation, regularity, stool consistency). Visits 2 and 3 will correspond to before (week 0) and after six weeks of supplementation, respectively, with the probiotic dietary supplement or placebo.

NCT ID: NCT05614544 Completed - General Anesthesia Clinical Trials

Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

Start date: August 16, 2022
Phase: Phase 1
Study type: Interventional

Part 1: To determine the doses of IV HSK3486 and propofol for use in Part 2, the abuse potential part of the study. Part 2: To evaluate the abuse potential of HSK3486 compared with propofol when administered IV to healthy nondependent, recreational CNS depressant drug users.