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NCT ID: NCT01581944 Completed - Fibroids Clinical Trials

Gonadotropin-releasing Hormone Agonist Prior to Myomectomy

Start date: January 2008
Phase: Phase 3
Study type: Interventional

Fibroids are common in the West Indian population (30-40% of reproductive women).Fibroids are benign growth in the womb or uterus and in order to preserve the fertility of women they, require an operation called myomectomy or shelling out of the fibroid. This procedure can be associated with large blood loss. In current practice some obstetricians use a gonadotropin releasing hormone agonist prior to the operation to reduce blood loss. Gonadotropin releasing hormone agonist is used in current gynaecological practice to treat women with heavy periods. In this study the investigators randomised women to either 2 or 3 doses of the gonadotropin agonist prior to their operation and no treatment. The intraoperative blood loss was measured. The study hypothesis: To determine whether administration of gonadotropin releasing hormone agonist prior to myomectomy reduces intraoperative blood loss.

NCT ID: NCT01277614 Completed - Diabetes Clinical Trials

Therapeutic Lifestyle Modifications to Reduce Burden of Chronic Disease

Start date: September 2010
Phase: N/A
Study type: Interventional

The investigators previously established that there was a high burden of disease among all categories of staff at the University of the West Indies, St. Augustine and in many ways, this group is typical of the working class of the Caribbean population. Many had poor lifestyle behaviors, 23.8% had Metabolic Syndrome (MS) with many having one or more MS components. Since most time is spent at work, the workplace is understandably the most logical location to address issues pertaining to health, disease prevention and wellness and on-site programs have yielded many health and other benefits to employees and employers alike. Onwards of the 1980s, numerous studies have been done on work-site intervention programs and these have shown that if a company is able to identify employees at risk for developing health problems and then intervene, health risks and the resulting medical problems are reduced. Such a program, if tailored to meet the needs of participants, may yield similar benefits among the staff of the University of the West Indies.

NCT ID: NCT00260858 Completed - Healthy Clinical Trials

GI Interlab 2 Study: Measuring the Glycaemic Index (GI) of Foods

Start date: November 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the extent of and sources of variation in the glycaemic index values of foods measured by different laboratories around the world.

NCT ID: NCT00178113 Completed - Clinical trials for Prostatic Intraepithelial Neoplasia

A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia

Start date: July 2003
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether dietary lycopene supplementation lowers serum prostate specific antigen(PSA) in men with high grade intraepithelial neoplasia (HGPIN).

NCT ID: NCT00102791 Terminated - Sickle Cell Disease Clinical Trials

A Stratified Sickle Event Randomized Trial (ASSERT)

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effects of ICA-17043 to placebo with or without hydroxyurea (an oral drug used for treatment of sickle cell disease) in patients with sickle cell disease who have had 2 or more acute sickle-related painful crises requiring a visit to a medical facility within the past 12 months.

NCT ID: NCT00011037 Completed - HIV Infections Clinical Trials

ALVAC-HIV vCP1452 Alone and Combined With MN rgp120

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test how the body's immune system responds to the vaccine ALVAC-HIV vCP1452 and to determine if the vaccine is safe when given alone and with MN rgp120. HIV infection and AIDS have no cure, in spite of recent advances in anti-HIV drugs. Many worldwide populations cannot afford the antiviral treatments for infected people. HIV vaccines offer hope for disease prevention. In this trial, 2 experimental HIV vaccines called ALVAC vCP1452 and MN rgp120 will be given to volunteers in Haiti, Brazil, Peru, and Trinidad and Tobago. The study will determine how volunteers' immune systems respond to the vaccines. (This protocol has been changed by adding new international sites.)