Clinical Trials Logo

Filter by:
NCT ID: NCT00874003 Completed - Alcohol Dependence Clinical Trials

The Effects of Mirtazapine Versus Placebo on Alcohol Consumption in Male Alcohol High Consumers

Start date: April 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to study the effects of 8 weeks of treatment with mirtazapine on alcohol consumption in alcohol high consuming men. This study is a randomized, double-blind placebo controlled clinical trial with parallel group design(N=59).

NCT ID: NCT00870350 Active, not recruiting - Tetanus Clinical Trials

An Immunogenicity and Safety Study of Tetanus, Diphtheria and Acellular Pertussis Vaccine Booster

Tdap Booster
Start date: April 2009
Phase: Phase 4
Study type: Interventional

Open-label, randomized, multi-centre study in which 400 subjects, divided into two groups, will receive Td5ap or Td1aP as a single injection. We will then describe the immune response and safety profile of the combined vaccine booster.

NCT ID: NCT00870155 Terminated - Clinical trials for Secondary Progressive Multiple Sclerosis

A Study for Patients With Multiple Sclerosis

MAESTRO-02
Start date: February 2007
Phase: Phase 2/Phase 3
Study type: Interventional

To obtain additional safety data in subjects who have previously completed the MBP8298-01 study "A Double Blind Placebo Controlled Multi-Centre to Evaluate the Efficacy and Safety of MBP8298 in Subjects with Secondary Multiple Sclerosis" Dirucotide is generic name for MBP8298.

NCT ID: NCT00870051 Completed - Clinical trials for Aortic Aneurysm, Abdominal

Endurant Stent Graft Natural Selection Global Postmarket Registry

ENGAGE
Start date: April 8, 2009
Phase:
Study type: Observational

The purpose of ENGAGE is to prospectively collect global 'real world' data on the Endurant Stent Graft System from AAA subjects.

NCT ID: NCT00869726 Completed - Clinical trials for Secondary Progressive Multiple Sclerosis

A Study for Patients With Secondary Progressive Multiple Sclerosis

MAESTRO-01
Start date: December 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether MBP8298 is effective and safe in the treatment secondary progressive multiple sclerosis. Dirucotide is generic name for MBP8298.

NCT ID: NCT00867048 Completed - HIV Infection Clinical Trials

Strategic Timing of Antiretroviral Treatment

START
Start date: April 15, 2009
Phase: Phase 4
Study type: Interventional

Objectives: - To find out if the chance of developing a serious illness or of getting AIDS is less if patients start taking HIV medicines at a time when their cluster-of-differentiation-4 (CD4)+ cell count is still fairly high, instead of waiting until the CD4+ count is at the level where there is good evidence for starting medicines. - To learn more about how a strategy of starting HIV medicines early might affect other aspects of care, such as the chances of developing other illnesses or resistance to HIV medicines, the frequency of doctor visits, the cost of medical care, and general health and satisfaction.

NCT ID: NCT00866762 Active, not recruiting - Polycythemia Vera Clinical Trials

A Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia

Start date: February 2009
Phase: Phase 2
Study type: Interventional

The aim of the present study is to evaluate the efficacy and safety of MK-0683 in the treatment of PV and ET. This agent has most recently been shown to be a potent inhibitor of the autonomous proliferation of haematopoietic cells of PV and ET patients carrying the JAK2 V617F mutation. Accordingly, it may be anticipated that MK-0683 - by decreasing the JAK2 allele burden - may influence clonal myeloproliferation and in vivo granulocyte, platelet and endothelial activation , which are considered to be major determinants of morbidity and mortality ( thrombosis, bleeding, extramedullary haematopoiesis , myelofibrosis ) in these disorders. The effects of MK-0683 at the molecular level will be studied by global/ focused gene expression profiling, epigenome profiling and proteomics.

NCT ID: NCT00866697 Completed - Ovarian Cancer Clinical Trials

Efficacy and Safety of Pazopanib Monotherapy After First Line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Start date: May 26, 2009
Phase: Phase 3
Study type: Interventional

This was a study to determine whether therapy with pazopanib was effective and safe in women with epithelial ovarian, fallopian tube, or primary peritoneal cancer whose cancer had not progressed on first line chemotherapy.

NCT ID: NCT00866502 Completed - Parkinson's Disease Clinical Trials

A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0031 to Patients With Parkinson's Disease

Start date: March 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This study is conducted to evaluate the safety and tolerability of the drug product sNN0031, containing Platelet Derived Growth Factor (PDGF), when administered directly into one of the fluid filled cavities in the brain using an implanted catheter and an implanted SynchroMed® II pump. Patients with a diagnosis of Parkinson's disease will be enrolled.

NCT ID: NCT00866281 Terminated - Clinical trials for Acute Myeloid Leukemia

A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia

Start date: September 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase I/II pediatric dose-ranging study that will evaluate the safety, tolerability, clinical response, pharmacokinetics and pharmacodynamics of midostaurin in patients <18 years of age who have relapsed or refractory acute leukemias that may benefit from administration of midostaurin, including MLL-rearranged ALL and FLT3 positive AML.