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NCT ID: NCT00151892 Completed - Ulcerative Colitis Clinical Trials

Efficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis

Start date: April 8, 2005
Phase: Phase 3
Study type: Interventional

Ulcerative colitis is a disease of the large bowel (colon) and rectum in which the lining of the bowel becomes red and swollen. Over time, patients with this disease may experience acute episodes of diarrhea, rectal bleeding and abdominal pain followed by periods of time without disease symptoms. 5-ASA drugs are a standard treatment for ulcerative colitis. Mesalazine is an experimental drug designed to gradually release 5-ASA into the areas of large bowel associated with ulcerative colitis. This study will test the safety and efficacy of mesalazine in keeping ulcerative colitis in remission.

NCT ID: NCT00151502 Completed - Alzheimer's Disease Clinical Trials

To Evaluate the Safety and Effectiveness of Atorvastatin Plus a Cholinesterase Inhibitor in AD Patients.

Start date: November 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out if atovastatin, when taken with a cholinesterase inhibitor, is effective for treating Alzheimer's disease.

NCT ID: NCT00151450 Completed - Anxiety Clinical Trials

Comparison of Pregabalin Versus Venlafaxine XR and Placebo in the Treatment of Generalized Anxiety Disorder

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare pregabalin to Venlafaxine XR and placebo in the treatment of generalized anxiety disorder.

NCT ID: NCT00150813 Completed - Clinical trials for Epilepsy, Tonic-clonic

Monotherapy With Levetiracetam in Patients Suffering From Epilepsy.

Start date: August 10, 2005
Phase: Phase 3
Study type: Interventional

An open-label follow-up trial assessing the long term safety of levetiracetam as per adverse events reporting.

NCT ID: NCT00150267 Completed - Ocular Hypertension Clinical Trials

A 5-Year Postmarketing Safety Study Of Xalcom In Patients With Open Angle Glaucoma Or Ocular Hypertension

Start date: February 2002
Phase: Phase 3
Study type: Interventional

To estimate the frequency of patients with ocular/periorbital adverse events. To identify any possible long-term adverse consequences of increased iris pigmentation and to follow serious adverse events throughout the study period.

NCT ID: NCT00148798 Completed - Clinical trials for Non Small Cell Lung Cancer (NSCLC)

Study of Cisplatin/Vinorelbine +/- Cetuximab as First-line Treatment of Advanced Non Small Cell Lung Cancer (FLEX)

FLEX
Start date: October 2004
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to investigate the efficacy of cetuximab in combination with chemotherapy in comparison to chemotherapy alone in patients with advanced non small cell lung cancer who did not received prior chemotherapy. Overall survival will be taken as primary measure of efficacy.

NCT ID: NCT00147602 Completed - Clinical trials for Cardiovascular Disease

Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke

SPARCL
Start date: November 1998
Phase: Phase 4
Study type: Interventional

To determine whether Lipitor reduces stroke, compared to placebo in patients who have had a previous stroke or transient ischemic attack.

NCT ID: NCT00145652 Completed - Multiple Myeloma Clinical Trials

Adjuvant I.V. Iron Therapy During Erythropoetin Treatment of Anemic Patients With Lymphoproliferative Disorders.

Start date: December 2003
Phase: Phase 3
Study type: Interventional

This is a multi-center open label, randomized phase-3 study with stratification according to diagnosis and baseline serum-EPO level. The correction of mild or moderate anemia and the effect on iron kinetics by the rHuEPO treatment with or without intravenous iron supplementation in anemic patients with LPD not receiving antineoplastic therapy will be studied. The study will be performed according to the ICH-GCP guidelines. In order to be eligible, the patient must consent in writing that he/she agrees to participate in the study. The patient recruitment period is estimated to be no longer than 18 months.

NCT ID: NCT00144196 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

12 Week Efficacy of Tiotropium Versus Placebo in Patients With Mild COPD According to Swedish Guidelines (SPIRIMILD)

Start date: March 11, 2004
Phase: Phase 4
Study type: Interventional

To show that treatment with tiotropium inhalation capsules (18 μg q.d.) via HandiHaler® improves lung function in patients with mild COPD according to Swedish guidelines.

NCT ID: NCT00144170 Completed - HIV Infections Clinical Trials

Tipranavir/Ritonavir vs. Genotypically Defined Protease Inhibitor/Ritonavir in HIV Patients (RESIST-2)

Start date: February 2003
Phase: Phase 3
Study type: Interventional

The objective of this study is to demonstrate the safety and efficacy of tipranavir/ritonavir versus an active control arm in highly treatment experienced Human immunodeficiency virus-1 infected patients. Patients must have a viral load > =1000 cells/mL, and genotype indicating at least one resistance conferring protease inhibitor-mutation as determined from a predefined panel of mutations. Any CD4+ count is acceptable.