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NCT ID: NCT02352974 Completed - Clinical trials for Diabetes Mellitus, Type 1

GAD-Alum (Diamyd) Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes (DIAGNODE-1)

DIAGNODE
Start date: January 2015
Phase: Phase 1
Study type: Interventional

The objectives of the main study is to: - Evaluate the safety of giving GAD-Alum (Glutamic acid decarboxylase) (Diamyd) directly into lymph glands in combination with an oral vitamin D regimen - Evaluate how the above mentioned treatments influence the immune system and endogenous insulin secretion. The objective of the sub-study is to: - Evaluate safety after a fourth injection with 4 μg GAD-Alum direct into an inguinal lymph gland in 3 adult patients from the main study - Evaluate how the above mentioned treatment influences the immune system and endogenous insulin secretion.

NCT ID: NCT02351089 Terminated - Gynecologic Cancer Clinical Trials

Probiotics in Radiation-treated Gynecologic Cancer

ProRad
Start date: February 2015
Phase: N/A
Study type: Interventional

The aim of the current Project is to study the efficacy of a probiotic Product in reducing the symptoms of gastrointestinal toxicity linked to the irradiation of gynecologic cancer.

NCT ID: NCT02351063 Terminated - Heart Failure Clinical Trials

HF Assessment With BNP in the Home: Part II

HABIT-II
Start date: April 2014
Phase: N/A
Study type: Interventional

HABIT-II is a feasibility study aimed at home monitoring of patients with heart failure. B-type natriuretic peptide (BNP) has strong correlations to the severity of heart failure. Lower BNP levels are closely associated with better clinical outcomes. The goal of HABIT-II is to demonstrate that the results of daily patient self-testing of BNP at home will provide sufficient information to guide physicians to modify therapy and lower BNP levels over time.

NCT ID: NCT02350257 Completed - Anxiety Disorders Clinical Trials

Internet-Based CBT for Children With Anxiety Disorders: Implementation in Clinical Settings

Start date: March 2015
Phase: N/A
Study type: Interventional

The primary objective of this study is to test the effectiveness of internet-delivered and therapist-guided internet-based cognitive behavior therapy (ICBT) for children with anxiety disorders (including social anxiety disorder, separation anxiety disorder, generalized anxiety disorder, panic disorder and specific phobia) in a randomized trial where participants will be allocated to either ICBT or to a supportive control condition. Non-responders (defined as those participants who still uphold their primary anxiety disorder after the ICBT treatment) will be offered traditional (face-to-face) CBT. Follow-ups are conducted at 3 and 12 months after treatment completion.

NCT ID: NCT02350153 Completed - Cushing Disease Clinical Trials

Cushing´s Disease Epidemiology in Sweden

Start date: September 2013
Phase:
Study type: Observational

The purpose of this study is to study since 1987 all patients diagnosed with CD in Sweden and determine their outcomes including mortality. A secondary objective is to focus on patients in remission and identify determinants of their different outcomes.

NCT ID: NCT02349815 Completed - Contraception Clinical Trials

JAYDESS Drug Utilization Study in Sweden

Start date: January 1, 2017
Phase:
Study type: Observational

- To describe characteristics (demographic, clinical, social) of first time users of Jaydess - To estimate the duration of use of Jaydess - To study switching patterns, e.g. what are the hormonal contraceptive methods used before and what are the methods after discontinuing Jaydess - To study off-label use of Jaydess

NCT ID: NCT02348619 Completed - Clinical trials for Obstructive Sleep Apnea

"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

OSA
Start date: May 2015
Phase: Phase 3
Study type: Interventional

This trial is a 6-week, double-blind, placebo-controlled, randomized-withdrawal, multicenter study of safety and efficacy of JZP-110 in the treatment of excessive sleepiness in adult subjects with OSA.

NCT ID: NCT02348489 Completed - Clinical trials for Leukemia, Myeloid, Acute

SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction

Start date: March 19, 2015
Phase: Phase 3
Study type: Interventional

To compare efficacy and safety between SGI-110 and Treatment Choice in adults with previously untreated AML who are not considered candidates for intensive remission induction chemotherapy.

NCT ID: NCT02347657 Completed - Cystic Fibrosis Clinical Trials

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor

Start date: January 2015
Phase: Phase 3
Study type: Interventional

This is a Phase 3, randomized, double blind, placebo controlled, parallel group, multicenter study in people with cystic fibrosis (CF) who are homozygous for the F508del CF transmembrane conductance regulator (CFTR) gene mutation.

NCT ID: NCT02347592 Completed - Peritoneal Dialysis Clinical Trials

Peritoneal Dialysis Catheter Function

Start date: November 2007
Phase: N/A
Study type: Interventional

The straight Tenckhoff is the most common catheter for peritoneal dialysis. A new, more expensive,self-locating catheter with a heavy tip has been developed by Di Paolo. The investigators used these catheters in parallel for several years. To clarify what catheter has least problems the investigators performed a comparative study to clarify if outflow problems differed between these catheters.