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NCT ID: NCT00625521 Completed - Clinical trials for Discoid Lupus Erythematosus

Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions

Start date: November 2006
Phase: Phase 2
Study type: Interventional

Lupus Erythematosus (LE) is an autoimmune disorder that includes a broad spectrum of clinical forms. One of these forms, Discoid Lupus Erythematosus (DLE) is a chronic disfiguring disease confined to the skin. The aim of this pivotal trial is to investigate the efficacy and safety of ASF-1096 cream 0.5% in the treatment of patients with DLE or SLE presenting newly developed discoid lesions.

NCT ID: NCT00624689 Completed - Infant Clinical Trials

Effects of Milk Fat Globule Membrane (MFGM) - Enriched Formula With Reduced Energy and Protein Content on Growth and Development

TUMME
Start date: March 2008
Phase: N/A
Study type: Interventional

Formula-fed infants differ from breast-fed infants in the growth pattern, risk for obesity and cardiovascular diseases, neurological development and morbidity in infections. The investigators' hypothesis is that a modified formula with reduced energy and protein content and enrichment with Milk Fat Globule Membrane (MFGM) containing bioactive proteins and phospholipids will reduce the difference between formula-fed and breast-fed infants.

NCT ID: NCT00623779 Completed - Clinical trials for Persistent or Permanent Non-valvular Atrial Fibrillation

Atrial Fibrillation (AF) Patients Not Taking Vitamin-K Antagonist (VKA)

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of AZD0837 in patients with atrial fibrillation who are unable or unwilling to take vitamin K antagonist therapy for up to 3 months.

NCT ID: NCT00622869 Completed - Clinical trials for Liver Transplantation

Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients

RAD
Start date: January 2008
Phase: Phase 3
Study type: Interventional

This trial was designed to address important issues that impact recipients of liver allografts as well as clinicians, ie, renal function, reduction or discontinuation of tacrolimus early post-transplantation, and progression rate of fibrosis in hepatitis C virus (HCV) positive patients.

NCT ID: NCT00622765 Completed - Obesity Clinical Trials

A Study of the Safety and Effectiveness of JNJ-16269110 (R256918) in Overweight and Obese Patients

Start date: November 2007
Phase: Phase 2
Study type: Interventional

This study investigates the effectiveness and safety of 12 weeks of treatment with JNJ-16269110 (R256918), in overweight and obese patients. The primary measure of effectiveness is the change in body weight at a clinically relevant dosage level during treatment. Additional measures include body mass index (BMI), DEXA (dual X-ray absorptiometry which is a specialized x-ray test that measures body composition), fasting glucose, lipid levels, and blood pressure. Safety assessments performed during the trial include laboratory tests, vital sign measurements, and adverse event reporting.

NCT ID: NCT00622583 Completed - Hernia Clinical Trials

International Hernia Mesh Registry

IHMR
Start date: September 1, 2007
Phase:
Study type: Observational

This is an open-label, multi-center, long-term, prospective hernia mesh registry. A minimum of 4,800 hernia patients will be enrolled from approximately 60 active sites globally

NCT ID: NCT00622284 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes

Start date: February 2008
Phase: Phase 3
Study type: Interventional

The objective of the current study is to investigate the efficacy, safety and tolerability of BI 1356 (5.0 mg daily) compared to glimepiride given for 104 weeks as add-on therapy to preferably > 1500 mg metformin in patients with type 2 diabetes mellitus with insufficient glycaemic control

NCT ID: NCT00621855 Completed - Coronary Disease Clinical Trials

RE-DEEM Dose Finding Study for Dabigatran Etexilate in Patients With Acute Coronary Syndrome

Start date: March 2008
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to evaluate the safety and indicators of efficacy of up to 4 doses of orally administered dabigatran etexilate, administered twice daily, compared to placebo when given in addition to dual antiplatelet treatment in patients with an index event (MI) at high risk for new ischaemic cardiovascular events.

NCT ID: NCT00621660 Completed - Nausea Clinical Trials

Acupuncture Versus Sham for Radiotherapy-Induced Emesis

Start date: January 2004
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate if acupuncture prevents or reduces nausea or vomiting during radiotherapy

NCT ID: NCT00621062 Completed - Varicose Veins Clinical Trials

Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein Incompetence

RAFPELS
Start date: January 2008
Phase: N/A
Study type: Interventional

Through a prospective RCT evaluate and compare the three new endovenous methods for great saphenous vein ablation (Radiofrequency, endovenous laser and foam sclerotherapy) versus high ligation and stripping. Procedure (proof-of-concept) and patient related (clinical outcome) factors will be studied.