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Hernia clinical trials

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NCT ID: NCT06369233 Recruiting - Herniation, Disc Clinical Trials

Clinical Study to Evaluate the Anti-adhesion Efficacy and Safety of MegaShield®-SP in Comparison With Guardix-SP Plus After Spine Surgery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

This study is Interventional, Parallel, Double-blinded, Randomized study. Subjects aged 20 to 70 years who had a Lumbar discectomy or laminectomy, MegaShield-SP® and Guardix-SP Plus will be applied.

NCT ID: NCT06367309 Not yet recruiting - Ventral Hernia Clinical Trials

ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair

ALPINE
Start date: April 30, 2024
Phase: N/A
Study type: Interventional

This study investigates on the effect of two different operative techniques to treat abdominal wall hernias. The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a better outcome than the IPOM (Intraperitoneal onlay mesh) technique. The main questions it aims to answer are: - pain after the operation - rate of complications - rate of recurrence and reoperations - quality of life. Participants will: Either be operated using the eTEP or the IPOM technique. Be followed up either in person or via email / phone call at day 1, day 7, day 14, 6 weeks, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes.

NCT ID: NCT06366581 Completed - Incisional Hernia Clinical Trials

Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology

Start date: March 1, 2023
Phase:
Study type: Observational

This study included patients who underwent surgical treatment for incisional hernia and non-hernia conditions. Surgical specimens were collected for transcriptome sequencing to obtain the gene expression list. Then genes analyzed by Gene Ontology, protein interactions, and signaling pathway enrichment using the expression matrix.

NCT ID: NCT06364306 Not yet recruiting - Incisional Hernia Clinical Trials

oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias

PRIOR
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair (RVHR) leads to a better outcome than the open ventral hernia repair (OVHR). The main questions it aims to answer are: length of stay after the operation rate of complications rate of recurrence and reoperations quality of life. Participants will: Either be operated using the eRVHR or OVHR will be followed up either in person or via email / phone call at day 7, day 30, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes.

NCT ID: NCT06356987 Completed - Inguinal Hernia Clinical Trials

Comparison of Laparoscopic Herniotomy and Open Herniotomy in Children

Herniotomy
Start date: June 1, 2021
Phase: N/A
Study type: Interventional

All patients of age 6 month to 12 years with inguinal hernia were included in study. Data was collected on detailed proforma regarding age, sex, side ,operative time, cosmesis , and postoperative complications

NCT ID: NCT06356844 Recruiting - Low Back Pain Clinical Trials

The Effect of Resolvins on the Resolve of Inflammatory Low Back Pain

Start date: February 27, 2024
Phase: N/A
Study type: Interventional

Brief Summary: Inflammatory back pain is a chronic condition localized in the axial spine and sacroiliac joints.1 It often accompanies mechanical issues like lumbar disc herniation. While non-surgical interventions such as medication, physiotherapy, and epidural steroid injections are typically the initial approach, surgical options may be considered if these prove ineffective.2 Resolvins, derived from omega-3 fatty acids, have shown promise in reducing inflammation and pain. They help to resolve inflammatory responses, promote tissue repair, and decrease disc size, potentially reducing the need for surgery.3,4 This clinical trial aims to evaluate the efficacy of adding oral resolvins to transforaminal epidural steroid injections for treating lumbar disc herniation (LDH) The control group (Group C: n=25) will receive epidural steroids, while the study group (Group R: n=25) will receive both oral omega-3 supplementation and epidural steroids on the same day. Additionally, the study group will continue taking oral omega-3 supplements for six months. The primary outcome measure will be changes in protruded/extruded disc size assessed via MRI, with secondary outcomes including pain levels measured by the Numeric Rating Scale (NRS) and serum cytokine levels (IL-6, IL-17, IL-1 beta, TNF-alpha) over the study period. Discussion: This trial anticipates that combining the anti-inflammatory properties of resolvins with epidural steroid injection will provide a beneficial treatment for patients suffering from inflammatory low back pain.

NCT ID: NCT06352489 Not yet recruiting - Ventral Hernia Clinical Trials

Evaluation of Posterior Component Separation Technique in the Management of Complex Ventral Hernia.

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

- Assess short term outcome of posterior component separation technique(PCS) including the regain of the physiological function of the abdominal wall. - Detect most common post operative complications related to AWR techniques in a 6 months duration after operation.

NCT ID: NCT06330857 Active, not recruiting - Fecal Incontinence Clinical Trials

Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy

Start date: May 28, 2002
Phase: N/A
Study type: Interventional

Several pelvic prolapses can render defecation difficulties and they are often treated with different surgical techniques. This study will evaluate a novel variation of a laparoscopic technique used to treat rectal prolapse that is modified to treat multiple pelvic prolapses. 25 women with symptoms of obstructed defecation and multiple pelvic prolapses are assessed before and after surgery with clinical examination, defecography and a questionnaire for bowel function and quality of life. Follow up was scheduled after three and twelve months and at long term (minimum ten years).

NCT ID: NCT06318156 Recruiting - Clinical trials for Lumbar Disc Herniation

Exploring the Distribution Patterns and Infrared Characteristics of Force-sensitive Acupoints in Different Lumbar Nerve Segments in Patients With LDH Based on "Press Quickly" Theory

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Utilizing the "responsive acupoint palpation" technique and infrared thermography, we investigated the distribution patterns of pressure-sensitive acupoints across different lumbar spinal segments in patients with lumbar disc herniation (LDH). Methodology: The Finger TPS tactile pressure measurement system was employed to conduct sensitivity examinations on the acupoints of the L1~L5 lumbar spine in 80 LDH patients (Group 1) and 80 healthy individuals (Group 2), applying a standardized force of 60N. When a sensation of comfort was elicited, the points were marked on a human cutaneous nerve segment map. We then utilized infrared thermography to collect and compare the temperature differences of the top 10 most frequently responsive acupoint areas in the experimental group against those in the control group.

NCT ID: NCT06317779 Not yet recruiting - Abdominal Disorder Clinical Trials

Evaluation of Laparoscopic Cholecystectomy and Concomitant Paraumbilical Hernia Repair

Start date: April 1, 2024
Phase:
Study type: Observational

Umbilical hernia frequently accompanies cholelithiasis. It is possible to repair these hernias after completing cholecystectomy.