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NCT ID: NCT04960865 Completed - Fatigue Clinical Trials

Kinesio Taping and Calf Muscle Fatigue

Start date: September 6, 2021
Phase: N/A
Study type: Interventional

Muscle fatigue results in decreased ability in muscles to generate force. Kinesio Tape may reverse the adverse effects of fatigue. Thus this study will examine the acute effects of Kinesio tape on muscle fatigue.

NCT ID: NCT04941131 Not yet recruiting - COVID-19 Clinical Trials

The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients

Start date: July 2021
Phase: Phase 4
Study type: Interventional

Existing evidence confirmed that saliva and oral cavity to be a reservoir for SARS-CoV-2. In dental clinic aerosol-producing-procedures pose a significant risk for transmission of the infection . It is very important to minimize the risk of transmission in dental office reducing the load of SARS-CoV-2 in saliva if possible, in suspect or conformed cases. Preprocedural mouth rises have been used widely to minimize the number of oral microorganisms. Multiple studies confirmed the efficacy of those mouth rinses in reducing the possibility of transmission of SARS-CoV-2 infection .

NCT ID: NCT04937660 Recruiting - Clinical trials for Metastatic Breast Cancer

Treatment Patterns & Clinical Outcomes of Palbociclib Combinations in HR+HER2-MBC

PRECIOUS
Start date: July 15, 2021
Phase:
Study type: Observational

The objective of this non-interventional multicenter study is to provide prospective, observational data on patients initiating treatment with palbociclib combination to contribute to the knowledge of HR+ HER2-metastatic/locally advanced Breast Cancer (BC) disease management, its treatment pattern, clinical outcomes and quality of life (QoL) in the routine clinical practice in Africa and Middle East countries .

NCT ID: NCT04937296 Completed - Clinical trials for Diabetes Mellitus, Type 2

Effects of Home-based Physical Activity in Saudi Arabian Type-2 Diabetes Mellitus Patients.

Start date: January 12, 2022
Phase: N/A
Study type: Interventional

The World Health Organization ranks Saudi Arabia as having the 7th highest rate of type-2 diabetes in the world. This therefore makes diabetes the most challenging health problem facing Saudi Arabia. Importantly, physical activity has been shown to improve disease symptoms and overall health in patients with type-2 diabetes. However, findings relating to the prevalence of physical inactivity in the Saudi population confirm that a sedentary lifestyle is on the rise, within physical inactivity levels in adults being 80.5%. Therefore, interventions aimed at reducing physical inactivity using bespoke modalities pertinent to Saudi Arabia are clearly warranted. The purpose of this research project is to undertake a feasibility randomised control trial, examining the effects of a 12-week home-based physical activity programme on HbA1c, blood lipids, fasting glucose and other indices of health-related quality of life in Saudi Arabian adults with type-2 diabetes.

NCT ID: NCT04935879 Active, not recruiting - Sickle Cell Disease Clinical Trials

A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises

Start date: October 26, 2021
Phase: Phase 3
Study type: Interventional

This Phase 3 study will assess the safety and efficacy of inclacumab, a P-selectin inhibitor, in reducing the frequency of vaso-occlusive crises (VOCs) in approximately 240 adult and adolescent participants (≥ 12 years of age) with sickle cell disease (SCD). Participants will be randomized to receive inclacumab or placebo.

NCT ID: NCT04932694 Completed - Surgery Clinical Trials

Optimizing Function Outcomes After Bariatric Surgery With Core Stabilization Training: A Randomized Controlled Study

Start date: June 21, 2021
Phase: N/A
Study type: Interventional

Bariatric surgery has been reported to be the most effective treatment option for losing and maintaining body weight and improving comorbidities and mortality associated with morbid obesity. Nevertheless, even though physical activity is recommended to optimize bariatric surgery results. Very little is known, about whether engaging in an exercise program after surgery can provide additional improvement in health outcomes. While to date there are relatively few researches studied the effect of exercise in patients who have undergone bariatric surgery.

NCT ID: NCT04927247 Terminated - Sickle Cell Disease Clinical Trials

A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises

Start date: December 13, 2021
Phase: Phase 3
Study type: Interventional

This Phase 3 study will assess the safety and efficacy of a single dose of inclacumab, a P-selectin inhibitor, for a vaso-occlusive crisis (VOC) after an index VOC in participants with sickle cell disease (SCD). Participants will be randomized to receive either inclacumab or placebo.

NCT ID: NCT04921839 Enrolling by invitation - Safety Issues Clinical Trials

Awareness of Operating Room Staff About WHO OR Checklist

Start date: June 10, 2021
Phase:
Study type: Observational

to understand and analyze awareness of proper timing of when to sing in, time out, and sign out for patients who will be operated in Hail multidisciplinary centers, Saudi Arabia. its role in improving communication in OR, and preventing errors. how frequent not comply and potentials of non compliance. how frequent dose WHO OR check list will cause anxiety in the staff, psychological insult ,potentials to be replaced or adjusted according to each specialty needs.

NCT ID: NCT04921826 Enrolling by invitation - Foreign Bodies Clinical Trials

Potential Causes of Retained Items During Surgery

Start date: June 10, 2021
Phase:
Study type: Observational

to understand and analyze the potential causes of retained items (sponge and instruments) during surgery, which include room preparations, initial count, adding sponges, removing sponges, first closing count, final closing count.

NCT ID: NCT04921462 Completed - Septoplasty Clinical Trials

Silastic Sheet Usefulness Following Septoplasty

Start date: September 29, 2020
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effectiveness of silastic septal splint in reducing the rates of complications, decreasing the post-operative pain, and improving satisfaction in comparison to quilting suturing technique. Methods: A single center randomized controlled trial, including adult above the age of 18. A total of 50 participants who underwent septoplasty were enrolled and randomly assigned into two groups, Silastic group (n=25), and quilting group (n=25). Nasal obstruction severity was assessed by using an Arabic validated version of NOSE score, preoperatively then 3 days, one week and one month postoperatively. Post-operative complications were assessed at outpatient clinic 1 week and 1 month postoperatively. Pain was assessed by a 10-point numerical scales via phone call on the 3rd day postoperative.