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NCT ID: NCT00760968 Completed - Clinical trials for Arthritis, Rheumatoid

Efficacy and Safety of TAK-783 in Subjects With Rheumatoid Arthritis

Start date: August 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of TAK-783, once daily (QD), taken in combination with methotrexate in subjects with rheumatoid arthritis.

NCT ID: NCT00760214 Completed - Hypertension Clinical Trials

Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of azilsartan medoxomil, once daily (QD), compared to ramipril for treating Essential Hypertension.

NCT ID: NCT00758953 Completed - Endometriosis Clinical Trials

Pain Associated With Endometriosis

Start date: February 2007
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of an investigational medication compared with placebo in the treatment of pain associated with endometriosis.

NCT ID: NCT00757848 Completed - Cystic Fibrosis Clinical Trials

A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis

INCA
Start date: October 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate if treatment with AZD9668 for 28 days is effective in treating Cystic Fibrosis (CF) and if so how it compares to placebo (a substance which does not have any action).

NCT ID: NCT00757588 Completed - Type 2 Diabetes Clinical Trials

Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin

Start date: November 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effects of saxagliptin with those of placebo as add-on therapy to insulin and insulin with metformin in improving glycemic control at 24 and 52 weeks.

NCT ID: NCT00756119 Completed - Clinical trials for Post Cardiac Surgery Patients

Measurement of Cardiac Output and Blood Volumes Using Transonic Ultrasound Dilution Technology

Start date: December 2006
Phase: N/A
Study type: Observational

Measurement of the amount of blood pumped by the heart (cardiac output) and blood volumes in sick patients is important for doctors to better treat these patients. Current procedures available demand difficult invasive procedures and hence these parameters are not measured with enough frequency and are also limited to certain patients. The new COstatus system is capable of using the already existing arterial and venous lines placed in critically ill patients and thus provides an opportunity to measure these parameters less invasively and with enough frequency. The purpose of this study is to measure cardiac output and blood volumes using ultrasound dilution technology (COstatus system)in post cardiac surgery adult patients and compare the cardiac output measurements with a current clinical reference method, thermodilution.

NCT ID: NCT00755755 Completed - Uterine Myomas Clinical Trials

PGL4001 Versus Placebo in Uterine Myomas

PEARLI
Start date: October 2008
Phase: Phase 3
Study type: Interventional

This trial will assess the efficacy and safety of PGL4001 with concomitant iron administration versus placebo with concomitant iron administration, over a 3-month period for the pre-operative treatment of pre-menopausal women suffering from excessive uterine bleeding due to uterine myoma.

NCT ID: NCT00755287 Completed - Clinical trials for Diabetes Mellitus Type 2

A Study of the Safety, Tolerability and Effect on Glycemic Control of Taspoglutide Versus Insulin Glargine in Insulin Naive Type 2 Diabetic Patients Inadequately Controlled With Metformin Plus Sulphonylurea.

Start date: November 2008
Phase: Phase 3
Study type: Interventional

This 3-arm study will assess the efficacy, safety and tolerability of taspoglutide compared to insulin glargine in patients with insulin-naive type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea combination therapy. Patients will be randomized to receive taspoglutide (10 mg once weekly, or 10mg once weekly for 4 weeks followed by 20mg once weekly) or insulin glargine (starting dose 10 IU/day) in a ratio of 1:1:1 in addition to continued prestudy metformin treatment. The anticipated time on study treatment is 2+ years, and the target sample size if 500+ individuals.

NCT ID: NCT00755053 Completed - Clinical trials for Vulvovaginal Candidiasis

Comparative Efficacy of Ovule vs Tablet

Start date: September 2008
Phase: Phase 3
Study type: Interventional

The study is focused to prove that the efficacy of a new Canesten formulation (ovule) is not inferior to the old Canesten formulation (tablet)

NCT ID: NCT00753545 Completed - Ovarian Cancer Clinical Trials

Assessment of Efficacy of AZD2281 in Platinum Sensitive Relapsed Serous Ovarian Cancer

Start date: August 28, 2008
Phase: Phase 2
Study type: Interventional

The primary purpose of this study to determine if AZD2281 is effective and well tolerated in maintaining the improvement in your cancer after previous platinum-based chemotherapy