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NCT ID: NCT01655680 Completed - Schizophrenia Clinical Trials

A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia

Start date: May 2012
Phase: Phase 2
Study type: Interventional

This is a safety and efficacy study evaluating a experimental treatment for cognitive deficits in adults with schizophrenia.

NCT ID: NCT01653912 Completed - Clinical trials for Recurrent Platinum-resistant Ovarian Cancer

Dose-finding Study in Platinum-Resistant Ovarian Cancer

Start date: November 2012
Phase: Phase 1/Phase 2
Study type: Interventional

- Dose-finding study of GSK2110183 administered in combination with carboplatin and paclitaxel to any subject with recurrent ovarian cancer. - Safety and efficacy study of GSK2110183 administered in combination with carboplatin and paclitaxel to subjects with platinum-resistant ovarian cancer.

NCT ID: NCT01652677 Completed - Stroke Clinical Trials

Navigation Repetitive Transcranial Magnetic Stimulation in Stroke Rehabilitation

NTMSR
Start date: January 2012
Phase: Phase 4
Study type: Interventional

The aim of research to study therapeutic possibilities of navigation transcranial magnetic stimulation in stroke rehabilitation, finding optimal protocol.

NCT ID: NCT01649856 Completed - Clinical trials for Lymphoma, Large B-Cell, Diffuse

A Study of Subcutaneous Versus Intravenous MabThera/Rituxan (Rituximab) in Combination With CHOP Chemotherapy in Patients With Previously Untreated CD20-Positive Diffuse Large B-Cell Lymphoma

Start date: August 24, 2012
Phase: Phase 3
Study type: Interventional

This multicenter, randomized, open label parallel-group study will evaluate the efficacy and safety of subcutaneous versus intravenous MabThera/Rituxan (rituximab) in combination with CHOP chemotherapy in patients with previously untreated CD20-positive diffuse large B-Cell lymphoma. Patients will be randomized to receive either MabThera/Rituxan 1400 mg subcutaneously or MabThera/Rituxan 375 mg/m2 intravenously on Day 1 of each cycle for 8 cycles, in combination with 6-8 cycles of CHOP chemotherapy. Anticipated time on study treatment is 6 months.

NCT ID: NCT01649557 Completed - Schizophrenia Clinical Trials

Multicenter, Open-label, Safety and Tolerability Study

STEP 210
Start date: August 2009
Phase: Phase 2
Study type: Interventional

This will be a multicenter, 52 week, open label study to assess the safety and tolerability of oral OPC-34712 (1 to 6 mg) as monotherapy in adult patients with schizophrenia. The study will be conducted on an outpatient basis. Enrollment into the study will be drawn from eligible subjects who have completed participation in Study 331-07- 203 and who, in the investigator's judgment, would benefit from continued treatment with oral OPC-34712.

NCT ID: NCT01649375 Completed - Clinical trials for Anklyosing Spondylitis

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis

MEASURE2
Start date: October 18, 2012
Phase: Phase 3
Study type: Interventional

This study assessed the efficacy and safety of secukinumab in patients with active ankylosing spondylitis who were tolerant to or had an inadequate response to NSAIDs, DMARDs and / or TNFα inhibitor

NCT ID: NCT01649297 Completed - Clinical trials for Diabetes Mellitus, Type 2

A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy

Start date: October 2012
Phase: Phase 2
Study type: Interventional

The aim of this study is to investigate the efficacy and safety of two doses (high and low) of empagliflozin as add-on therapy to metformin in patients with type 2 diabetes mellitus (T2DM) and insufficient glycaemic control. Both doses may be given once daily or split to a twice daily dosage. This results in 4 different dosage regimens of empagliflozin (high dose once daily or split vs. low dose once daily or split). This is done to evaluate whether a twice daily dose regimen of empagliflozin results in a loss of efficacy relative to once daily dosing when given on top of metformin background therapy.

NCT ID: NCT01648582 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus

AWARD-CHN2
Start date: July 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine if once-weekly dulaglutide is efficient and safe compared to once-daily insulin glargine in participants with type 2 diabetes mellitus who have inadequate glycemic control with 1 or 2 oral antihyperglycemic medications (OAM) (metformin and/or a sulfonylurea), in addition to any healthy lifestyle changes recommended by their healthcare providers.

NCT ID: NCT01647516 Completed - Ulcerative Colitis Clinical Trials

Efficacy and Safety Study of Ozanimod in Ulcerative Colitis

Touchstone
Start date: December 26, 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether RPC1063 is effective in the treatment of ulcerative colitis (UC).

NCT ID: NCT01647451 Completed - Clinical trials for Rheumatoid Arthritis

A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy of NNC0114-0006 in Subjects With Active Rheumatoid Arthritis

Start date: September 2012
Phase: Phase 2
Study type: Interventional

This trial is conducted in Europe. The aim of the trial is to evaluate the change in disease activity following intravenous (i.v.) administration of two doses of NNC0114-0006 compared to placebo in subjects with active rheumatoid arthritis (RA) on background methotrexate (MTX) therapy.