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NCT ID: NCT04574453 Completed - Clinical trials for Osteoarthritis, Knee

Study To Assess The Efficacy And Safety Of The Medical Device Iracross Versus Iraline Administered Intra-Articular To Patients With Knee Osteoarthritis

Start date: June 29, 2020
Phase: N/A
Study type: Interventional

Comparison with a non-inferiority design at 12 and 24 weeks on a larger scale is real to objectively evaluate the composite measurement of ROM, pain and basic activities like walking or performing daily activities (QoL) in a population with a large coverage of age and levels of physical activity (from no physical activity history to athletes).

NCT ID: NCT04573322 Completed - Clinical trials for SARS-CoV-2 (Covid19)

Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects

Start date: September 10, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This study will assess the safety and efficacy of TSC as a treatment for participants who are infected with SARS-CoV-2 (COVID-19).

NCT ID: NCT04565990 Completed - Clinical trials for Hypertension, Pulmonary

A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study

SOMBRERO
Start date: May 3, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the long-term safety of selexipag while providing continued selexipag treatment for participants who were previously enrolled in an Actelion-sponsored study with selexipag and who derived benefit from selexipag in indications for which a positive benefit-risk has been established.

NCT ID: NCT04565379 Completed - COVID19 Pneumonia Clinical Trials

Clinical Trial to Investigate the Efficacy and Safety of NuSepin® in COVID-19 Pneumonia Patients

Start date: September 24, 2020
Phase: Phase 2
Study type: Interventional

A randomized, double blind, placebo-controlled, phase 2 clinical trial to investigate the efficacy and safety of 2 doses of NuSepin® intravenous infusion in COVID-19 pneumonia patients

NCT ID: NCT04537923 Completed - Type 2 Diabetes Clinical Trials

A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

SURPASS-6
Start date: October 19, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to insulin lispro (U100) three times a day in participants with type 2 diabetes that are already on insulin glargine (U100), with or without metformin.

NCT ID: NCT04535986 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Start date: September 29, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of ensifentrine in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

NCT ID: NCT04533256 Completed - Sepsis Clinical Trials

Effects of Renal Replacement Therapy With Hemoadsoption in Patients With Sepsis

Start date: July 10, 2016
Phase:
Study type: Observational [Patient Registry]

Hemoadsorption has been demonstrated to improve clinical and paraclinical results in critically ill patients with sepsis and septic shock. The present study investigates the effects of three consecutive sessions of hemoadsorption, performed in accordance to the local protocol for treating patients with sepsis, on organ failure, severity scores and 30-days mortality. Paraclinical results and severity scores were obtained before and after the three consecutive sessions.

NCT ID: NCT04522180 Completed - Acromegaly Clinical Trials

A Study to Assess the Safety, Tolerability, and Efficacy of IONIS-GHR-LRx Administered in Patients With Acromegaly

Start date: January 4, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety, tolerability, and efficacy of IONIS-GHR-LRx subcutaneous (SC) injection as monotherapy in patients with acromegaly.

NCT ID: NCT04516759 Completed - Covid19 Clinical Trials

AZD1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19

ARCADIA
Start date: August 12, 2020
Phase: Phase 2
Study type: Interventional

The ARCADIA Trial is a randomised, double-blind, placebo-controlled clinical trial to assess the safety and efficacy of AZD1656 in patients with either Type 1 or Type 2 diabetes, hospitalised with COVID-19.

NCT ID: NCT04513262 Completed - Clinical trials for Surgery--Complications

Effects of Video-Assisted Surgery on Ventilatory Parameters

Start date: March 20, 2015
Phase:
Study type: Observational

The study investigates the effects of induced pneumoperitoneum during surgery on ventilatory parameters including peak inspiratory pressure, lung compliance, end-tidal CO2 at specific time-points: after induction of anaesthesia, after induction of surgery, one-hour and two-hours during surgery, end of surgery. The effects of pneumoperitoneum are compared between two groups of patients: patients undergoing laparoscopic surgery and patients undergoing robotic-assisted surgery. No intervention was performed in this study and the decision for type of surgery performed was made by the attending surgeon prior to study inclusion