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Osteoarthritis, Knee clinical trials

View clinical trials related to Osteoarthritis, Knee.

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NCT ID: NCT03921801 Recruiting - Clinical trials for Osteoarthritis, Knee

Effects of Improved Calf Muscle Function on Gait, Balance and Joint Loading in Older Adults

Start date: December 21, 2018
Phase: N/A
Study type: Interventional

This study investigates role of calf muscle function for gait performance, balance and knee joint loading. Previous studies have linked age-related loss of calf muscle function with impairments in gait performance and balance, and increased loading of the areas of knee joint that are susceptible for development of osteoarthritis. In this study, an exercise intervention is used to target structural and neural aspects of impaired calf muscle function with aging. The intervention includes 14 weeks of strength training for the calf muscles and training sessions to enhance calf function during walking. The study will test whether the intervention is effective in improving walking speed, reduce metabolic cost of walking, improve standing balance and reduce knee joint loading.

NCT ID: NCT03921749 Recruiting - Clinical trials for Osteoarthritis, Knee

Radial Versus Focused Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis

Start date: April 20, 2019
Phase: N/A
Study type: Interventional

Radial versus Focused Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis : A Randomized Control Trial

NCT ID: NCT03920020 Recruiting - Knee Osteoarthritis Clinical Trials

Comparison of The Effects of Concentric And Eccentric Isokinetic Exercises in Patients With Knee Osteoarthritis

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in 69 patients with knee osteoarthritis enrolled the study.

NCT ID: NCT03918681 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Gait Retraining Enhances Athletes' Technique

GREAT
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The participant population for this study will be a convenience sample of 40 active duty soldiers and cadets at West Point, New York (NY) who are recovering from anterior cruciate ligament reconstruction (ACLR) and are cleared to return to run by their medical provider. Two groups will be utilized in this pre-test, post-test, single-blind randomized controlled trial study design. The purpose of this study is to determine if patients recovering from ACLR benefit from running gait retraining to adopt a forefoot strike pattern and 5-10% increase in step rate when compared to a traditional walk to run program.

NCT ID: NCT03918291 Completed - Clinical trials for Osteoarthritis of Knee

Whole-body Vibration Training on Functional Performance of the Elderly With Knee Osteoarthritis

Start date: October 28, 2008
Phase: N/A
Study type: Interventional

The present study evaluated the effects of adding whole body vibration to squat training on the isometric quadriceps muscle strength, the plasma concentration of brain-derived neurotrophic factor at rest in elderly woman with osteoarthritis of the knee. The eligible patients were fifteen elderly women ≥ 60 years of age who had been diagnosed with osteoarthritis of the knee. The intervention consisted of uninterrupted squatting exercises for 12 weeks, a 3x/week. The exercise protocol was similar in both groups differed only in the presence of vibration.

NCT ID: NCT03915756 Not yet recruiting - Clinical trials for Osteoarthritis, Knee

Postoperative Drainage in Total Knee Arthroplasty in the Presence of Tranexamic Acid

Start date: May 2019
Phase: N/A
Study type: Interventional

The investigator's aim with this study is to address, with the new paradigm of tranexamic acid, the role of wound drainage following total knee arthroplasty in blood loss, blood transfusion requirements and functional recovery

NCT ID: NCT03915522 Recruiting - Knee Osteoarthritis Clinical Trials

Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty

Start date: May 14, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectivity of adductor canal block performed the day after total knee arthroplasty surgery in reducing pain and improving walking ambulation ability and muscle strength.

NCT ID: NCT03913442 Not yet recruiting - Osteoarthritis Clinical Trials

Colchicine for the Treatment of Osteoarthritis of the Knee

CLOAK
Start date: May 15, 2019
Phase: Phase 4
Study type: Interventional

This prospective, double-blinded, placebo-controlled, randomized trial will enroll 120 SKOA subjects at the NYU Center for Musculoskeletal Care. Patients meeting entry criteria will be randomized 1:1 to treatment with colchicine or placebo daily for 3 months. Subjects will have detailed evaluation of standardized clinical pain outcomes, candidate peripheral blood biomarkers, baseline knee radiographs as well as MSK-US, and a subset will undergo evaluation of their synovial fluid.

NCT ID: NCT03913052 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Intra-articular Viscosupplement Application in Knee Osteoarthritis

Start date: November 2, 2018
Phase: N/A
Study type: Interventional

Knee osteoarthritis (OA) is one of the common diseases which causes pain and disability with increasing age. In developed countries, it is said to be one of the ten diseases which decreases functionality most.

NCT ID: NCT03912610 Not yet recruiting - Clinical trials for Osteoarthritis, Knee

Study on Brain Structure and Function of Pain-related Emotion Disorder

Start date: May 2019
Phase:
Study type: Observational

By the method of multi-mode Magnetic Resonance Imaging, 5 patients with knee osteoarthritis are selected in this trial to observe the possible differences in the brain structure and function from the 5 healthy volunteers.