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NCT ID: NCT00315640 Completed - Eye Diseases Clinical Trials

Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of anecortave acetate depot when administered for the treatment of elevated IOP following treatment with steroids.

NCT ID: NCT00313313 Completed - Diabetes Clinical Trials

A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas

Start date: April 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to understand if adding saxagliptin to a sulfonylurea is safe and works better than increasing the amount of sulfonylurea a patient takes

NCT ID: NCT00312845 Completed - Clinical trials for Non-Hodgkin's Lymphoma

Study of VELCADE and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the combination of VELCADE and rituximab improves progression free survival relative to rituximab alone in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma (B-NHL) who never received rituximab or who have previously responded to rituximab. This is an international study being conducted in the United States and in many countries around the world. A complete list of study locations is listed below.

NCT ID: NCT00307164 Completed - HIV Infections Clinical Trials

Effects of a Uridine Supplement on HIV Infected Adults With Lipoatrophy

Start date: September 2006
Phase: Phase 2/Phase 3
Study type: Interventional

Lipoatrophy, the loss of body fat from particular areas of the body, is a common side effect of antiretroviral therapy (ART). The purpose of this study was to determine the effectiveness of uridine supplementation in treating HIV infected individuals on stable ART with lipoatrophy.

NCT ID: NCT00303602 Completed - Schizophrenia Clinical Trials

Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index (A Ratio of Weight to Height)

Start date: March 2006
Phase: Phase 4
Study type: Interventional

This study is testing if under the tongue olanzapine for schizophrenia, related psychosis, schizoaffective disorder or bipolar disorder will have less weight gain than olanzapine that is swallowed, in patients who are already gaining weight on olanzapine.

NCT ID: NCT00303485 Completed - Clinical trials for Post Menopausal Osteoporosis

A Study of Bone Turnover Markers in Post-Menopausal Women With Osteoporosis Treated With Monthly Boniva (Ibandronate)

Start date: February 2006
Phase: Phase 4
Study type: Interventional

This study will determine the rapidity of suppression of the bone resorption marker sCTX in post-menopausal women with osteoporosis.Other bone turnover markers will also be evaluated. Patients will be randomised to either monthly Boniva 150mg or placebo, in combination with vitamin D and calcium supplementation. The anticipated time on study treatment is 3-12 months, and the target sample size is <100 individuals.

NCT ID: NCT00300274 Completed - Graft Rejection Clinical Trials

Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection

Start date: January 2006
Phase: Phase 3
Study type: Interventional

This trial was to examine the impact of everolimus and reduced dose of cyclosporine on efficacy and safety compared to mycophenolate mofetil and a standard dose of cyclosporine in heart transplant recipients.

NCT ID: NCT00298350 Completed - HIV Clinical Trials

Ritonavir-Boosted GS-9137 vs. Ritonavir-Boosted Protease Inhibitor(s) in Combination With Background ART.

Start date: February 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the non-inferiority of ritonavir-boosted GS-9137 relative to a ritonavir-boosted Comparator Protease Inhibitor when used as part of combination antiretroviral regimens in subjects who have failed, or are failing, protease inhibitor therapy.

NCT ID: NCT00295750 Completed - Prostate Cancer Clinical Trials

The Efficacy and Safety of Degarelix One Month Dosing Regimens in Prostate Cancer

Start date: February 2006
Phase: Phase 3
Study type: Interventional

The study was a three-arm, active-control, multi-centre, parallel group study.

NCT ID: NCT00295633 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn whether Saxagliptin added to thiazolidinedione (TZD) therapy is more effective than TZD alone as a treatment for Type 2 diabetic subjects who are not sufficiently controlled with TZD alone