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NCT ID: NCT00281593 Completed - Hypertension Clinical Trials

Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension

Start date: April 2006
Phase: Phase 3
Study type: Interventional

To identify dose combinations of telmisartan and ramipril that are more effective in reducing diastolic blood pressure than each of the respective monotherapies in patients with Stage I or II hypertension.

NCT ID: NCT00279331 Completed - HIV Infections Clinical Trials

Estimating the Incidence of HIV Infection Among Men Who Have Sex With Men in Peru and Ecuador

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this observational study is to estimate the number of new HIV infections and the number and variability of antiretroviral-resistant HIV strains among men who have sex with men (MSM). Participants will be recruited from four sites in Peru and one site in Ecuador.

NCT ID: NCT00272779 Completed - HIV Infections Clinical Trials

BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and antiviral effects of atazanavir (ATV) plus ritonavir (RTV) versus a combination drug of lopinavir (LPV) plus RTV. A combination drug containing tenofovir (TDF) and emtricitabine (FTC) will also be taken by participants in both arms.

NCT ID: NCT00269516 Completed - Clinical trials for Early Stage Parkinson's Disease

SLV308 for Treatment of Patients With Early Parkinson's Disease

Start date: June 2006
Phase: Phase 3
Study type: Interventional

This study is a multicenter, randomized, double blind, parallel group study of 6 months' treatment with SLV308 administered as a monotherapy in patients with early stage PD. An open label safety extension to this study is planned as a separate protocol for patients who are willing and eligible to participate.

NCT ID: NCT00265382 Terminated - Schizophrenia Clinical Trials

Safety And Tolerability Of Ziprasidone In Adolescents With Schizophrenia

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of ziprasidone during long-term open-label administration in adolescents (ages 13-17) with schizophrenia.

NCT ID: NCT00263042 Terminated - Clinical trials for Cardiovascular Disease

Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints and Outcomes

CRESCENDO
Start date: December 2005
Phase: Phase 3
Study type: Interventional

The primary objective is to show whether rimonabant reduces the risk of a heart attack (MI), stroke, or death from an MI or stroke in patients with abdominal obesity with other cardiovascular (CV) risk factors. The secondary objective is to show whether rimonabant reduces the risk of MI, stroke, CV death, or CV hospitalization in these patients.

NCT ID: NCT00262600 Completed - Stroke Clinical Trials

Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate

Start date: December 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to demonstrate the efficacy and safety of dabigatran etexilate in patients with non-valvular atrial fibrillation for the prevention of stroke and systemic embolism.

NCT ID: NCT00262067 Active, not recruiting - Clinical trials for Metastatic Breast Cancer

A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metastatic Breast Cancer (RIBBON 1)

Start date: December 2005
Phase: Phase 3
Study type: Interventional

This is a Phase III, multicenter, randomized, placebo-controlled trial designed to evaluate the efficacy and safety of bevacizumab in combination with chemotherapy compared with chemotherapy alone in subjects with previously untreated metastatic breast cancer.

NCT ID: NCT00261846 Completed - Clinical trials for Chronic Myeloid Leukemia

Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive Leukemias

Start date: March 2006
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label, continuous daily dosing, two-part safety and efficacy study of SKI-606 (bosutinib) in Philadelphia chromosome positive leukemias (Ph+). Part 1 is a dose-escalation study in chronic phase Chronic Myelogenous Leukemia (CML) subjects to establish the maximum tolerated dose (MTD) in this subject population. Part 2 has begun after the completion of Part 1 and after a dose has been established for the compound in chronic phase subjects. Part 2 is a study of the the efficacy of 500mg daily oral SKI-606 (bosutinib) in patients with all phases of Ph+ CML and Ph+ Acute Lymphocytic Leukemia (ALL). The protocol will test the hypotheses that oral daily dosing of bosutinib at 500 mg will attain (1) Major Cytogenetic Response (MCyR) in chronic phase CML patients and (2) Overall Hematological Response (OHR) in advanced leukemia patients. Each phase of the disease will be evaluated as a separate cohort.

NCT ID: NCT00261365 Completed - Clinical trials for Unresectable Stage III or IV Malignant Melanoma

Phase II Study to Determine Predictive Markers of Response to BMS-734016 (MDX-010)

Start date: November 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to identify candidate markers predictive of response and/or serious toxicity to BMS-734016 (MDX-010).