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NCT ID: NCT00391872 Completed - Clinical trials for Acute Coronary Syndrome

A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome

PLATO
Start date: October 2006
Phase: Phase 3
Study type: Interventional

Ticagrelor is a new, reversible binding, anti-platelet medication. Anti-platelet medications work to prevent the formation of blood clots. Ticagrelor is being developed as a treatment for patients with acute coronary syndrome (ACS). ACS is a term that is used to describe both heart attacks in progress or the imminent threat of a heart attack. ACS is usually caused by the formation of a blood clot in an artery that partially or totally blocks the blood supply to a portion of the heart muscle. Ticagrelor will be compared with clopidogrel to determine which drug, when either is used in conjunction with aspirin, is better at reducing deaths from vascular causes, future heart attacks and/or strokes in patients with ACS.

NCT ID: NCT00391287 Completed - Clinical trials for Chronic Kidney Failure

Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia Among Patients With Chronic Kidney Failure

PRIMS
Start date: June 2006
Phase: Phase 4
Study type: Observational

The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) epoetin alfa (polysorbate 80 formulation) for the treatment of anemia associated with chronic renal failure (CRF), and to compare this incidence rate to the incidence rate with s.c. exposure to other currently marketed recombinant erythropoietin products (epoetin alfa, epoetin beta, darbepoetin alfa), with adjustment of duration for which the drug is given to the patient. The study will also examine the impact of the pattern of using mixed s.c. exposure to multiple erythropoietin products occurring in this patients, and the impact of the time from which the treatment is started to the onset of PRCA.

NCT ID: NCT00391027 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Clinical Trial Comparing the Efficacy and Safety of Exubera® and Lantus®

Start date: December 2006
Phase: Phase 4
Study type: Interventional

To compare efficacy and safety of Exubera® vs Lantus® in patients with type 2 diabetes mellitus.

NCT ID: NCT00387088 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Tiotropium / Respimat One Year Study in COPD.

Start date: September 2006
Phase: Phase 3
Study type: Interventional

The objective of the study is to evaluate the long-term (one year) efficacy and safety of tiotropium delivered by the Respimat inhaler in patients with COPD. Specifically, the study will examine the effect of treatment on COPD exacerbations.

NCT ID: NCT00385840 Completed - Influenza Clinical Trials

Study to Evaluate the Immunogenicity and Safety of a Second Vaccination With the Adjuvanted Influenza Vaccine Candidate

Start date: October 20, 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity and the safety of a second vaccination with candidate vaccine compared to Fluarix™ administered intramuscularly in elderly aged 60 years and above

NCT ID: NCT00385229 Completed - Perinatal Morbidity Clinical Trials

Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy

Start date: September 2002
Phase: N/A
Study type: Interventional

Post term pregnancy is a risk pregnancy. Aim of the study was to investigate whether induction of labor at gestational age 289(41 weeks+2 days) reduces neonatal morbidity compared to expectant management. Secondary aims was to assess the effect on mode of delivery and maternal complications, as well as assess women's views and experiences. Our 0-hypothesis was that induction of labor at gestational age 41+2 did not result in better outcome of pregnancy, measured as perinatal morbidity. Following inclusion, women were randomly allocated to induction of labor or to monitoring of pregnancy every third day until delivery

NCT ID: NCT00384852 Completed - Fractures Clinical Trials

A Study of rhBMP-2/CPM in Closed Fractures of the Humerus

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess whether fracture union is accelerated in subjects with humeral fractures (proximal,diaphyseal) treated with conservative therapy (standard of care) and a single dose of rhBMP-2/CPM compared to subjects who receive standard of care alone.

NCT ID: NCT00384358 Completed - Fractures Clinical Trials

Feasibility And Safety Study Of rhBMP-2/CPM For Hip Fractures

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess the safety of administering rhBMP-2/CPM as an adjuvant to internal fixation in subjects with fractures of the proximal femur.

NCT ID: NCT00379626 Terminated - Paraphilia Clinical Trials

Cognitive and Hormonal Treatment of Sex Offenders

Start date: August 2003
Phase: Phase 1
Study type: Interventional

The aim of this study is to determine if Cognitive treatment and hormone treatment can change the relapse rate of sexual offenders.

NCT ID: NCT00378248 Active, not recruiting - Clinical trials for Personality Disorders

Ullevål PersonalityProject

Start date: May 2004
Phase: N/A
Study type: Interventional

Ullevål PersonalityProject is a ranomized controlled trial of treatment of patients with personality disorder. It's main purpose is to test the effect of a long-term combined treatment program compared with eclectic individual therapy for patients with personality disorders. The main study hypothesis is that long-term combined treatment is superior to eclectic individual therapy with respect to improvement in personality functioning, psychosocial functioning, symptoms, interpersonal problems, and self destructive behavior for poorly functioning patients with personality disorders.