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NCT ID: NCT00420927 Completed - Clinical trials for Rheumatoid Arthritis

Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis

OPTIMA
Start date: December 2006
Phase: Phase 4
Study type: Interventional

This study compared the safety and efficacy of combination therapy with adalimumab plus methotrexate (MTX) to that of MTX monotherapy (i.e., placebo plus MTX) in subjects with early rheumatoid arthritis (RA).

NCT ID: NCT00420914 Terminated - Thrombocytopenia Clinical Trials

Strategies for Transfusion of Platelets (SToP)

Start date: October 2003
Phase: Phase 3
Study type: Interventional

To evaluate the hemostatic efficacy of a low dose platelet transfusion strategy compared to a standard dose platelet transfusion strategy.

NCT ID: NCT00420485 Completed - Solid Tumors Clinical Trials

Dose-escalation Study of Gimatecan Administered in Two Different Schedules in Adult Patients With Advanced Solid Tumors

Start date: March 2006
Phase: Phase 1
Study type: Interventional

This study will evaluate the Maximum Tolerated Dose and dose limiting toxicity of gimatecan administered orally in patients with advanced solid tumors

NCT ID: NCT00419146 Completed - Schizophrenia Clinical Trials

Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants

Start date: September 2001
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this trial is to study the effect of adding the omega-3 fatty acid EPA and/or Vitamins E + C to antipsychotic drugs in younger patients with schizophrenia and related psychoses.

NCT ID: NCT00418223 Completed - Urinary Retention Clinical Trials

Detecting Urinary Retention After Child Birth With a Ultrasound Scanner

Start date: November 2005
Phase: Phase 4
Study type: Observational

The purpose of this study is a systematical registration of ultrasound measurements and urinary volume after catheterization. Based on these pairs of measurements we will calculate the reliability of ultrasound compared with catheter volume.

NCT ID: NCT00417911 Completed - Multiple Myeloma Clinical Trials

Efficacy of Bortezomib Consolidation After High-dose Melphalan With Stem Cell Support in Myeloma Patients

Start date: December 2005
Phase: Phase 3
Study type: Interventional

Multiple myeloma is a malignant incurable hematological disease where survival has been significantly improved by high-dose melphalan with autologous stem cell support (ASCT) in younger patients. However, the disease will eventually relapse and new treatment is demanded. Bortezomib is a newly approved drug for treating relapsing multiple myeloma. It has a different biological effect and response even in patients refractory to conventional chemotherapy. The purpose of the study is in a randomized design to investigate if addition of bortezomib by 20 injections during a 4 months period starting 3 month after ASCT can prolong the time to progression compared to patients receiving no consolidation or maintenance therapy.

NCT ID: NCT00417508 Terminated - Malnutrition Clinical Trials

Nutritional Intervention in Malnourished Elderly Patients

Start date: December 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate whether nutritional supplementation will improve functional outcome parameters and nutritional status in elderly patients.

NCT ID: NCT00417209 Completed - Clinical trials for Pancreatic Neoplasms

Larotaxel Compared To Continuous Administration of 5-FU in Advanced Pancreatic Cancer Patients Previously Treated With A Gemcitabine-Containing Regimen

PAPRIKA
Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and the safety Larotaxel administered as single agent every 3 weeks to continuous administration of 5-FU every 3 weeks, in patients with advanced pancreatic cancer (non operable in a curative intent, locally recurrent or metastatic) previously treated with gemcitabine based therapy.

NCT ID: NCT00415363 Completed - Clinical trials for Non Small Cell Lung Cancer

Study of Enzastaurin Versus Placebo in the Treatment of Patients With Brain Metastases of Lung Cancer, After Whole Brain Radiation Therapy

Start date: December 2006
Phase: Phase 2
Study type: Interventional

This study is a multinational study to compare enzastaurin versus placebo in the treatment of patients with brain metastases of lung cancer. Approximately 108 patients will be randomly assigned to receive either enzastaurin or placebo after having completed whole brain radiotherapy.

NCT ID: NCT00414609 Completed - Clinical trials for Myocardial Infarction

Safety and Efficacy of Aliskiren in Post Myocardial Infarction Patients (ASPIRE)

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The core and extension studies assessed the safety and efficacy of aliskiren when added to optimized standard therapy in patients that have had a high risk acute myocardial infarction (heart attack).