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NCT ID: NCT00733018 Completed - Clinical trials for Cardiovascular Diseases

Nutrigenomics Diet Intervention Study Comparing Effects of Western and Balanced Diet in Healthy Subjects

Foodgene
Start date: December 2007
Phase: N/A
Study type: Interventional

Diet macronutrient relative composition, quality and quantity determines lifestyle disease, including cardiovascular disease, development. Our hypothesis is that a high content of carbohydrates in the diet contributes to increased insulin level. Moreover, activating enzymes promoting inflammatory processes and possibly chronic disease development in the body.

NCT ID: NCT00731822 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

A Study To Assess Single Dosage Strength Of GW685698/GW642444 Chronic Obstructive Pulmonary Disease (COPD)

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of a single dosage strength of GW685698/GW642444 in subjects with Chronic Obstructive Pulmonary Disease (COPD).

NCT ID: NCT00731549 Completed - Schizophrenia Clinical Trials

Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia

ASPIRE
Start date: December 2008
Phase: Phase 3
Study type: Interventional

To evaluate the overall effectiveness of aripiprazole intramuscular (IM) depot as maintenance treatment in patients with schizophrenia.

NCT ID: NCT00730054 Completed - Acute Pain Clinical Trials

Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers

Remiclon
Start date: February 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model. Of interest is also the effect of the combination on respiration, sedation and cognitive behavior.

NCT ID: NCT00729898 Completed - Clinical trials for Diabetes Mellitus, Type 2

Observational Study to Observe the Safety of NovoMix® 30 Treatment in Patients With Type 2 Diabetes

Start date: March 2008
Phase: N/A
Study type: Observational

This study is conducted in Europe. The study aims to observe the incidence of serious adverse drug reactions in patients with type 2 diabetes during NovoMix® 30 treatment.

NCT ID: NCT00729027 Terminated - Clinical trials for Hypercholesterolemia

Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing Statins in Patients With Primary Hypercholesterolemia

Start date: July 2008
Phase: Phase 3
Study type: Interventional

The present study is assessing the efficacy and safety of AVE5530 (25 mg and 50 mg) in add-on to ongoing statin treatment in a double-blind manner in comparison with placebo, in the management of patients with primary hypercholesterolemia considered as inadequately controlled despite their ongoing statin treatment. The main objective is to evaluate the effects of the association AVE5530+statin on LDL-C level reduction after 12 weeks of treatment. The effects of AVE5530 on other lipid parameters will be assessed as secondary objectives.

NCT ID: NCT00727714 Completed - Clinical trials for Systemic Inflammation

Lung Function and Inflammatory Markers in Cement Dust Exposed Workers: A Cross-shifts Study

LIS
Start date: April 2008
Phase: N/A
Study type: Observational

The aim of the study is to examine possible changes in lung function, nitric oxide levels and systemic inflammatory markers in cement dust exposed workers, during one shift (6-8 hours).

NCT ID: NCT00725985 Completed - Multiple Sclerosis Clinical Trials

Oral Cladribine in Early Multiple Sclerosis (MS)

ORACLE MS
Start date: December 31, 2008
Phase: Phase 3
Study type: Interventional

A randomized, double-blind, clinical trial to assess the safety and efficacy of two doses of oral cladribine versus placebo in participants who had a first clinical demyelinating event (clinically isolated syndrome). Participants in either the cladribine or placebo group may also enter treatment periods with open-label interferon-beta or open-label cladribine depending upon the disease status. The primary objective of this study is to evaluate the effect of two dosage regimens of oral cladribine versus placebo on the time to conversion to multiple sclerosis (MS) (from randomization) according to the Poser criteria in participants with first clinical demyelinating event at high risk of converting to MS.

NCT ID: NCT00722982 Active, not recruiting - Coxarthrosis Clinical Trials

Migration Pattern of C-stem AMT Versus Exeter in Total Hip Arthroplasty

Start date: July 2008
Phase: N/A
Study type: Observational

Hypothesis: Migration of C-Stem AMT is equal to the well documented Exeter prosthesis In Norway it is annually performed approximately 600 primary and 100 revisions THA. Osteolysis around the prosthesis is one of the major difficulties while performing revision surgery. C-stem is a triple tapered cemented prosthesis designed to increase the stress and strain of proximal femur and thereby decreasing osteolysis. We are planning til include 70 patients and randomize to C-stem AMT or Exeter prosthesis. Both prosthesis will be combined with previously non documented "Marathon" acetabular prosthesis. The result will be followed clinically and with RSA and DXA. Soft endpoint after 2 years

NCT ID: NCT00722267 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

European Non-interventional Study in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: July 2008
Phase:
Study type: Observational

This study is investigating how patients with severe stable state COPD perceive the variability of their symptoms throughout the day, the week and the year; the impact of these variations on their daily activities or sleep quality and how they deal with their treatments. For this purpose patients will be asked to answer a questionnaire over the phone