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NCT ID: NCT00548704 Completed - Extravasation Clinical Trials

A Clinical Trial on Topotect® (Dexrazoxane) in the Treatment of Accidental Extravasation of Anthracyclines

Start date: April 2002
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is - To prevent progression of a lesion caused by anthracycline extravasation into necrosis, which would require surgical intervention - To prevent development of deep tissue necrosis and destruction leading to impaired limb function and neurological deficit - To prevent postponement of the scheduled cancer treatment due to the treatment of the extravasation

NCT ID: NCT00548405 Completed - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study Two

CARE-MS II
Start date: October 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study was to establish the efficacy and safety of two different doses of alemtuzumab (Lemtrada™) as a treatment for relapsing-remitting multiple sclerosis (MS), in comparison with subcutaneous interferon beta-1a (Rebif®). The study enrolled participants who had received an adequate trial of disease-modifying therapies but experienced at least 1 relapse during prior treatment, and who met a minimum severity of disease as measured by magnetic resonance imaging (MRI). Participants had monthly laboratory tests and comprehensive testing every 3 months.

NCT ID: NCT00548314 Completed - Burns Clinical Trials

Dermal Substitute and Topical Negative Pressure in Burns

VAC-M
Start date: October 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether a treatment of full thickness wounds by the dermal substitute Matriderm, split skin graft and VAC treatment will improve scar quality, demonstrated by a significant increase of skin elasticity parameters after 3 months. Additionally, an increase of the take of graft and improvement of scar assessment scale, scar colour/pigmentation and time to complete wound closure, is expected.

NCT ID: NCT00547989 Completed - Breast Cancer Clinical Trials

Paravertebral Block, an Adjunct to General Anaesthesia for Breast Surgery?

Start date: October 2006
Phase: Phase 3
Study type: Interventional

Aim is to study if a paravertebral block as an adjunct to general anesthesia is a suitable technique for extended, one sided, breast surgery.

NCT ID: NCT00547859 Completed - Cardiac Surgery Clinical Trials

Relationship Between Microcirculatory Flow Alterations and Tissue Metabolism

Start date: November 2007
Phase: N/A
Study type: Observational

The purpose of this study is to correlate microcirculatory flow and rectal anaerobe cellular CO2 production in patients after cardiac surgery. The hypothesis is that such a correlation exists.

NCT ID: NCT00547651 Completed - Clinical trials for Small Cell Lung Cancer

AMR PH GL 2007 CL001 Phase 3 Trial in Patients With Small Cell Lung Cancer After Failure of First-Line Chemotherapy

Start date: September 1, 2007
Phase: Phase 3
Study type: Interventional

This study drug (Amrubicin) is believed to work by stopping the tumor cells in your body from growing. The purpose of this study is to evaluate the effect of amrubicin compared to topotecan in the treatment of small cell lung cancer.

NCT ID: NCT00546637 Completed - Clinical trials for Overactive Bladder Syndrome

Fesoterodine "add-on" Male Overactive Bladder Study

Start date: November 2007
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of fesoterodine on overactive bladder symptom improvement when added to ongoing alpha blocker treatment.

NCT ID: NCT00545818 Completed - Clinical trials for Jaw, Edentulous, Partially

Study Comparing OsseoSpeed™ Implants of Two Different Lengths in the Upper and Lower Posterior Jaw

Start date: November 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to see if OsseoSpeed™ implant 6 mm long is effective for rehabilitation of edentulism and if so, how it compares with OsseoSpeed™ implant 11 mm long. The primary hypothesis is that the alteration in bone level is equal in patients randomized to 6 mm as to patients randomized to 11 mm implants.

NCT ID: NCT00545415 Completed - Healthy Clinical Trials

The Effect of Fruit and Fruit Juice on Plasma Total Antioxidant Capacity

Start date: January 2008
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effect of consumption of a fruit beverage on plasma antioxidant capacity with that of the consumption of fruit.

NCT ID: NCT00545103 Completed - Diverticulitis Clinical Trials

Prevention of Recurrence of Diverticulitis

PREVENT2
Start date: December 6, 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether SPD476 is effective in reducing recurrence of diverticulitis.