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NCT ID: NCT01634113 Completed - Asthma Clinical Trials

Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo in 1 to 5 Year Old Patients With Persistent Asthma

Start date: July 2012
Phase: Phase 2
Study type: Interventional

The primary objective of this trial is to evaluate the safety and efficacy of two doses of tiotropium inhalation solution delivered via the Respimat® inhaler once daily in the afternoon in patients (1 to 5 years old) with persistent asthma on top of inhaled corticosteroid (ICS) treatment.

NCT ID: NCT01633411 Completed - Barrett's Esophagus Clinical Trials

Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Barrett's Epithelium

Start date: December 2011
Phase:
Study type: Observational

This is a feasibility study without a primary study hypothesis or statistical comparison.

NCT ID: NCT01631864 Completed - Hypertension Clinical Trials

Evaluation of the Metabolic Effects of LCZ696 and Amlodipine in Obese Hypertensive Subjects

Start date: October 2012
Phase: Phase 2
Study type: Interventional

This study investigated the effects of LCZ696 on insulin sensitivity, lipolysis, and oxidative metabolism in obese hypertensive subjects.

NCT ID: NCT01631422 Completed - Healthy Volunteer Clinical Trials

A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers

Start date: June 2012
Phase: Phase 1
Study type: Interventional

This single-center, open-label study will investigate the pharmacokinetics and elimination of a radiolabelled dose of RO4602522 in healthy male volunteers. The healthy male volunteers will receive a single oral dose of RO4602522.

NCT ID: NCT01631214 Completed - Clinical trials for Postmenopausal Women With Osteoporosis

Study to Determine the Efficacy and Safety of Romosozumab in the Treatment of Postmenopausal Women With Osteoporosis

ARCH
Start date: May 4, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if treatment is effective in preventing fractures in women with postmenopausal osteoporosis.

NCT ID: NCT01630512 Completed - Depressive Symptoms Clinical Trials

Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behavioral Therapy (CBT) for Depression in Diabetes Patients

Start date: May 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether mindfulness-based cognitive therapy (MBCT)and cognitive behavioral therapy (CBT)are effective in reducing depressive symptoms in patients with diabetes.

NCT ID: NCT01629043 Completed - Parkinson's Disease Clinical Trials

Parkinson's Foundation Quality Improvement Initiative

PF-QII
Start date: July 2009
Phase:
Study type: Observational

In a recent study it was found that neurologist care for Parkinson's provides a 20% reduction in nursing home placement, hip fracture, and death (Willis 2011). However, as the authors recognized, the investigators don't know what it is about expert care that delivers this benefit. The Parkinson's Foundation's Quality Improvement Initiative was designed to identify the components of great care that yield great outcomes. By capturing demographics, clinical interventions and outcomes over time from multiple centers across the U.S, Canada and internationally, the best care practices from different clinics and different healthcare systems will be analyzed.

NCT ID: NCT01628913 Completed - Clinical trials for Pancreatic Neuroendocrine Tumors (pNET)

Efficacy and Safety of BEZ235 Compared to Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors

MACS1938
Start date: October 2012
Phase: Phase 2
Study type: Interventional

This study will estimate the treatment effect of BEZ235 relative to everolimus on progression-free survival (PFS) in patients with advanced progressive pancreatic neuroendocrine tumors.

NCT ID: NCT01628588 Completed - Ocular Hypertension Clinical Trials

Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Start date: March 2010
Phase: N/A
Study type: Observational

This is an observational study of Lumigan® 0.01% (bimatoprost) treatment in clinical practice for patients with Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

NCT ID: NCT01628458 Completed - Clinical trials for Locally Advanced Pancreatic Cancer

Safety Study of Radiofrequency Ablation of Locally Advanced Pancreatic Cancer

RFA of LAPC
Start date: September 2012
Phase: Phase 2
Study type: Interventional

The purpose of the study is to determine the safety of radiofrequency ablation of locally advanced pancreatic cancer that can not be surgically removed with the current standard procedures. Complications after the operation will be registered. Moreover a pain score will be determined, length of hospital stay, chemotherapy, survival, progression free survival and a tumour marker.