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NCT ID: NCT02654171 Completed - Clinical trials for RESPIRATORY SYNCYTIAL VIRUS INFECTIONS

Viral Inhibition in Children for Treatment of RSV

VICTOR
Start date: May 27, 2016
Phase: Phase 2
Study type: Interventional

VICTOR is a randomized, double-blind, placebo-controlled, multicenter, 2-part study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antiviral effect of single and multiple dosing of AK0529 in infants hospitalized with RSV infection.

NCT ID: NCT02652481 Completed - Clinical trials for Magnetic Resonance Imaging

ENABLE MRI (Magnetic Resonance Imaging)

ENABLE-MRI
Start date: January 2016
Phase: N/A
Study type: Interventional

The objective of this study is to collect data to confirm the safety and effectiveness of the Image Ready™ MR (Magnetic Resonance) Conditional Defibrillation System when used in the 1.5T (Tesla) MRI environment under the labeled Conditions of Use (Phase I). Additionally, the study will assess medically necessary MR scans according to the labeled Conditions of Use to provide real-world scanning data (Phase I and Phase II).The study also aims to demonstrate the continued ability of the ImageReady MR Conditional Defibrillation System to sense and detect ventricular fibrillation (VF) post MRI scan by collecting and analyzing data from spontaneous VF episodes, "for-cause" VF inductions, and from an optional VF induction Sub-study. .

NCT ID: NCT02648347 Completed - Anemia Clinical Trials

Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease

Start date: December 2015
Phase: Phase 3
Study type: Interventional

A multicenter, randomized, open-label, active-controlled Phase 3 study for the correction of anemia and maintenance of hemoglobin (Hb) in participants with Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD)

NCT ID: NCT02648217 Completed - Clinical trials for Diabetes Mellitus, Type 2

Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart Twice Daily and Biphasic Insulin Aspart Twice Daily in Subjects With Type 2 Diabetes Mellitus Before, During and After Ramadan

Start date: January 4, 2016
Phase: Phase 3
Study type: Interventional

This trial is conducted in Africa and Asia. The aim of this trial is to compare efficacy and safety of insulin degludec/insulin aspart twice daily and biphasic insulin aspart twice daily in subjects with type 2 diabetes mellitus before, during and after Ramadan.

NCT ID: NCT02646072 Completed - Diabetes Mellitus Clinical Trials

Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients

Start date: August 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract surgery.

NCT ID: NCT02640664 Completed - Clinical trials for Retinopathy of Prematurity (ROP)

Rainbow Extension Study

RainbowExt
Start date: June 16, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the long term efficacy and safety of intravitreal ranibizumab compared with laser ablation therapy in patients who were treated for retinopathy of prematurity (ROP) in the core study CRFB002H2301 (NCT02375971)

NCT ID: NCT02640612 Completed - Clinical trials for Arthritis, Rheumatoid

Long-term Assessment of Safety and Efficacy of BI 695501 in Patients With Rheumatoid Arthritis

Start date: January 22, 2016
Phase: Phase 3
Study type: Interventional

The main objective of this trial is to provide long-term safety, pharmacokinetics (PK), and immunogenicity data on BI 695501 administered via prefilled syringe in patients with Rheumatoid Arthritis who have completed Trial 1297.2. The primary endpoint thereby is the number (proportion) of patients with drug-related adverse events (AEs) during the treatment phase. The secondary objective in this trial is the assessment of Long-term efficacy of BI 695501 by evaluation of: - the change from Baseline in DAS28 (ESR) at Week 48 - the proportion of patients meeting American College of Rheumatology 20% (ACR20) response criteria at Week 48 - the proportion of patients who meet the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) definition of remission at Week 48 - the proportion of patients with EULAR response (good response, moderate response, or no response) at Week 48.

NCT ID: NCT02629575 Completed - Clinical trials for Coronary Artery Disease (CAD)

Coroflex ISAR 2000 Registry

ISAR2000
Start date: January 2014
Phase: N/A
Study type: Observational [Patient Registry]

Postmarket surveillance in terms of the safety and efficacy of Sirolimus-eluting Coroflex ISAR Stent for the treatment of "real world" patients with de-novo and restenotic lesions after stand-alone angioplasty in coronary arteries

NCT ID: NCT02624869 Completed - Clinical trials for Familial Hypercholesterolemia

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

HAUSER-OLE
Start date: September 10, 2016
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to describe the safety and tolerability of 80 weeks of subcutaneous (SC) evolocumab when added to standard of care in children 10 to 17 years of age with familial hypercholesterolemia.

NCT ID: NCT02617693 Completed - Clinical trials for Diabetes Mellitus, Type 2

Development of Pre-pregnancy Intervention to Reduce the Risk of Diabetes and Prediabetes

Jom Mama
Start date: November 23, 2015
Phase: Phase 4
Study type: Interventional

This study is conducted in Asia. The aim of this study is to assess the efficacy of a pre-pregnancy life style intervention to reduce the risk of diabetes and prediabetes.