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NCT ID: NCT00062582 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Roflumilast on Pulmonary Function and Respiratory Symptoms in Patients With Chronic Obstructive Pulmonary Disease (COPD) (BY217/M2-110)

Start date: June 2003
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare the effect of roflumilast and placebo on the lung function in patients with COPD.

NCT ID: NCT00061022 Completed - Stroke, Acute Clinical Trials

Safety and Effectiveness of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke

Start date: May 2003
Phase: Phase 3
Study type: Interventional

This study will determine if NXY-059 will improve recovery from an acute stroke. The study is designed to look at both overall recovery and recovery of motor function, for example muscle strengthen and coordination.

NCT ID: NCT00059306 Completed - Hypertension Clinical Trials

Secondary Prevention of Small Subcortical Strokes Trial

SPS3
Start date: February 2003
Phase: Phase 3
Study type: Interventional

The goal of this study is to learn if combination antiplatelet therapy (aspirin and clopidogrel) is more effective than aspirin alone for the prevention of recurrent stroke and cognitive decline, and if intensive blood pressure control is associated with fewer recurrent strokes and cognitive decline. On July 21, 2011 the DSMB recommended terminating the anti platelet arm of the study due to an imbalance of overall and major non-CNS hemorrhagic SAE's and total deaths in the investigational anti platelet combination of aspirin + clopidogrel and an interim statistical analysis that demonstrated futility in the investigational anti platelet arm. It was recommended that patients be continued on standard care of aspirin mono therapy until their study close-out visit. Also, recommended the continuation and completion of the plood pressure arm following the protocol.

NCT ID: NCT00058838 Completed - Parkinson Disease Clinical Trials

Study Evaluating Sumanirole for the Treatment of the Signs and Symptoms of Early Parkinson's Disease

Start date: April 2003
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to determine whether sumanirole, at three different dose levels, is effective and safe in the treatment of the signs and symptoms of early Parkinson's disease

NCT ID: NCT00057317 Completed - Diabetes Clinical Trials

Study of Ro 205-2349 in Patients With Type 2 Diabetes Mellitus

Start date: December 2001
Phase: Phase 2
Study type: Interventional

The objective of the study is to determine the dose(s) of Ro 205-2349 which, when compared to placebo, are efficacious, safe and tolerable in improving glycemic control in patients with type 2 diabetes. Doses of 5 to 20 mg/day will be studied.

NCT ID: NCT00057304 Completed - Diabetes Clinical Trials

Study to Determine the Efficacy, Safety, Tolerability & Pharmacokinetics of RO 205-2349 in Patients With Type 2 Diabetes Mellitus

Start date: June 2003
Phase: Phase 2
Study type: Interventional

The objective of the study is to determine the dose(s) of Ro 205-2349 which, when compared to placebo, are efficacious, safe and tolerable in improving glycemic control in patients with type 2 diabetes. Doses of 2 to 5 mg/day will be studied.

NCT ID: NCT00056407 Completed - Neoplasms, Prostate Clinical Trials

"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk

REDUCE
Start date: March 2003
Phase: Phase 3
Study type: Interventional

This 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are defined by the study entrance criteria as being at an increased risk for prostate cancer. Study visits to the clinic will occur every 6 months for up to 4 years (10 clinic visits), and a prostate biopsy will be performed at 2 and 4 years of treatment.

NCT ID: NCT00053560 Active, not recruiting - Lupus Clinical Trials

To Assess Prevention of Bone Loss in Women With Lupus Receiving Treatment With Glucocorticoids

Start date: December 2002
Phase: Phase 3
Study type: Interventional

The purpose of this clinical trial is to study the effects of GL701 on bone mineral density in women with active systemic lupus erythematosus (SLE) who are also receiving treatment with glucocorticoids (e.g., prednisone).

NCT ID: NCT00050947 Completed - Epilepsy Clinical Trials

Pediatric Epilepsy Study

Start date: July 2002
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and effectiveness of oxcarbazepine (Trileptal) as monotherapy in the treatment of partial seizures in pediatric patients 1 month to 3 years of age.

NCT ID: NCT00050934 Completed - Epilepsy Clinical Trials

Pediatric Epilepsy Study

Start date: June 2002
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and effectiveness of oxcarbazepine (Trileptal) as add-on therapy in the treatment of partial seizures in pediatric patients 1 month to 3 years of age.