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NCT ID: NCT00542789 Completed - Clinical trials for Rheumatoid Arthritis

Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID

Start date: August 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy of esomeprazole (D961H) 20 mg versus placebo once daily for up to 24 weeks of treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily nonsteroidal anti-inflammatory drug (NSAID) therapy by evaluating presence or absence of gastric and/or duodenal ulcers throughout the treatment period (24 weeks) in terms of efficacy on prevention of gastric and/or duodenal ulcers

NCT ID: NCT00540670 Completed - Clinical trials for Coronary Artery Disease

A Double-Blind Study of E5555 in Japanese Subjects With Coronary Artery Disease

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of E5555 in Japanese subjects with coronary artery disease.

NCT ID: NCT00540436 Completed - Clinical trials for Hypertension, Pulmonary

Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial Hypertension

Start date: August 2007
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the effect of GSK1325760A on improvement in exercise capacity in subjects with pulmonary arterial hypertension (PAH). The secondary objectives of this study are to evaluate administration of GSK1325760A on: - The safety and tolerability - Improvement of PAH - The steady-state plasma pharmacokinetics of GSK1325760A

NCT ID: NCT00540423 Completed - Clinical trials for Purpura, Thrombocytopenic, Idiopathic

Clinical Evaluation of SB-497115-GR in Chronic Idiopathic Thrombocytopenic Purpura (ITP)

Start date: September 2007
Phase: Phase 3
Study type: Interventional

This is a Phase II/III multicenter study comprising of the double-blind, followed by open-label phases to evaluate and compare the efficacy and tolerability of eltrombopag (SB-497115-GR) in chronic ITP patients

NCT ID: NCT00538174 Completed - Clinical trials for Diabetes Mellitus, Type 2

Phase I Multiple-Ascending Dose (Japan)

MAD
Start date: November 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) following once daily oral doses of 2.5, 10, and 20 mg of dapagliflozin in diabetic Japanese subjects administered for 14 days

NCT ID: NCT00537485 Completed - Clinical trials for Early Parkinson's Disease

A Placebo-controlled Study for SPM 962 in Early Parkinson's Disease Patients

Start date: September 2007
Phase: Phase 2/Phase 3
Study type: Interventional

To investigate superiority of SPM 962 over placebo in early Parkinson's disease patients in a multi-center, placebo-controlled, double-blind study following once-daily multiple transdermal doses of SPM 962 within a range of 4.5 to 36.0 mg (12-week dose titration/maintenance period)

NCT ID: NCT00537082 Completed - Multiple Sclerosis Clinical Trials

Efficacy and Safety of FTY720 in Patients With Relapsing Multiple Sclerosis (MS)

Start date: September 2007
Phase: Phase 2
Study type: Interventional

To provide efficacy and safety data of two doses (0.5 mg and 1.25 mg) of FTY720 in Japanese patients with relapsing multiple sclerosis (MS)

NCT ID: NCT00534196 Completed - Prostate Cancer Clinical Trials

Implant Radiation Therapy Using Radioactive Iodine in Treating Patients With Localized Prostate Cancer

J-POPS
Start date: July 2005
Phase:
Study type: Observational

RATIONALE: Implant radiation therapy delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. PURPOSE: This clinical trial is studying the side effects and how well implant radiation therapy using radioactive iodine works in treating patients with localized prostate cancer.

NCT ID: NCT00533377 Completed - Tibial Fractures Clinical Trials

ACTiF- Assessment of Closed Tibial Fractures

Start date: January 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out the good and bad effects of an investigational drug called CP-533,536 in patients with closed fracture of the tibial shaft undergoing internal fixation using reamed inter-locked IM nailing procedure

NCT ID: NCT00532506 Completed - Clinical trials for Type 2 Diabetes Mellitus

Phase II Dose-Finding Study of SK-0403 With Type 2 Diabetes Mellitus

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the clinical efficacy and safety of SK-0403 in patients with Type2 Diabetes Mellitus