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NCT ID: NCT02372344 Completed - Healthy Clinical Trials

A Study to Investigate the Effect of Food on Pharmacokinetics of Total EPA and Total DHA of AZD0585 in Healthy Male Japanese Subjects

Start date: March 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the effect of food timing on pharmacokinetics (PK) of AZD0585 and the effect of food timing on tolerability and safety of AZD0585 in healthy male Japanese subjects.

NCT ID: NCT02372097 Completed - Healthy Clinical Trials

A Phase 1, Bioequivalence Study of SYR-472 25mg and 50mg Tablets

Start date: March 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the bioequivalence of 2 tablets of SYR-472 25 milligram (mg) and 1 tablet of SYR-472 50 mg administered to healthy adult males.

NCT ID: NCT02371174 Completed - Breast Cancer Clinical Trials

Post-Marketing Surveillance Study of Eribulin on the Status and Factors for the Development of Peripheral Neuropathy in Japan.

Start date: September 3, 2014
Phase:
Study type: Observational

The primary objective of the study is to clarify factors affecting the incidence of peripheral neuropathy in patients treated with HALAVEN. A total of 590 patients will be enrolled in this study with 295 patients in the treatment group of primary or secondary chemotherapy and 295 patients in the treatment group of tertiary or later chemotherapy.

NCT ID: NCT02370615 Completed - Clinical trials for Japanese Healthy Adult Males

A Phase 1, Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of TAK-272 and the Effect of TAK-272 on the Pharmacokinetics of Digoxin and Midazolam

Start date: February 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the effect of repeated-dose administration of itraconazole on the pharmacokinetics of TAK-272 and the effect of repeated-dose administration of TAK-272 on the pharmacokinetics of digoxin and midazolam in healthy Japanese adult males.

NCT ID: NCT02369874 Completed - Clinical trials for Recurrent or Metastatic PD-L1-positive or -Negative Squamous Cell Carcinoma of the Head and Neck SCCHN

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

EAGLE
Start date: September 9, 2015
Phase: Phase 3
Study type: Interventional

This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of MEDI4736 + tremelimumab combination therapy and MEDI4736 monotherapy versus SoC therapy in the target patient population.

NCT ID: NCT02367885 Completed - Influenza Infection Clinical Trials

Phase 1/2 Study of TAK-850 Intramuscular Injection in Healthy Pediatric Participants

Start date: February 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of an intramuscular injection of TAK-850 in healthy pediatric Japanese participants.

NCT ID: NCT02367872 Completed - Hepatic Impairment Clinical Trials

Phase I Open-label Study to Evaluate Pharmacokinetics of TAK-272 in Participants With Renal or Hepatic Impairment

Start date: March 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to examine the effects of renal and hepatic impairment on TAK-272 pharmacokinetics with a single oral administration of TAK-272 in participants with renal or hepatic impairment.

NCT ID: NCT02367794 Completed - Clinical trials for Squamous Non-Small Cell Lung Cancer

A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower131]

Start date: June 11, 2015
Phase: Phase 3
Study type: Interventional

This randomized, open-label study will evaluate the safety and efficacy of atezolizumab (MPDL3280A) in combination with carboplatin + paclitaxel or carboplatin + nab-paclitaxel compared with treatment with carboplatin + nab-paclitaxel in chemotherapy-naive participants with Stage IV squamous NSCLC.

NCT ID: NCT02367131 Completed - Clinical trials for Diabetes Mellitus, Type 2

Daily Use of JARDIANCE® Tablets in Japanese Elderly Patients With Type 2 Diabetes Mellitus

Start date: February 24, 2015
Phase:
Study type: Observational

Study to investigate the safety and efficacy of daily use of JARDIANCE® Tablets in Japanese elderly patients with type 2 diabetes mellitus.

NCT ID: NCT02366962 Completed - Influenza Clinical Trials

A Study to Assess the Safety of ASP7374 in Adult Subjects Aged 20 or Older

Start date: February 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the safety until Day 29 after injection of a single dose of quadrivalent vaccine ASP7374 in adult subjects aged 20 or older