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NCT ID: NCT03353402 Recruiting - Melanoma Stage Iv Clinical Trials

Fecal Microbiota Transplantation (FMT) in Metastatic Melanoma Patients Who Failed Immunotherapy

Start date: November 30, 2017
Phase: Phase 1
Study type: Interventional

Altering the Gut Microbiota of Melanoma Patients Who Failed Immunotherapy Using Fecal Microbiota Transplantation (FMT) From Responding Patients. FMT includes both colonoscopy and stool capsules.

NCT ID: NCT03348358 Recruiting - Stress Clinical Trials

Effect of Music on Stress and Delivery

Start date: January 23, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to randomize women to be exposed during labor to different genres of music and study the effect of each genre on the level of objective and subjective stress as manifested by salivary cortisol and personal stress questionnaires, respectively. Secondary outcomes to be examined are obstetric and perinatal outcomes

NCT ID: NCT03343691 Recruiting - Breast Cancer Clinical Trials

Blood Test for Early Detection of Breast Cancer Using Todos Medical -Breast 1(TM-B1) Assay

TM-B1
Start date: January 22, 2018
Phase:
Study type: Observational

Blood samples from a total of 200 women in two cohorts will be collected and analyzed by TM-B1 assay, which is based on TBIA (Total Biochemical Infrared Analysis) to confirm the presence of cancer. These two cohorts will yield 75 healthy women with no pathological findings, 75 women diagnosed as having benign breast tumor and 50 women diagnosed as having breast cancer.

NCT ID: NCT03340441 Recruiting - Clinical trials for Temperature Change, Body

Prizma Device Temperature Measurement

Prizma
Start date: April 19, 2017
Phase: N/A
Study type: Observational

The purpose of the study is to evaluate the temperature measurements by the Prizma device.

NCT ID: NCT03334708 Recruiting - Pancreatic Cancer Clinical Trials

A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma

Start date: October 30, 2017
Phase:
Study type: Observational

The purpose of this study is to develop a minimally invasive test to diagnose pancreatic cancer at early stages of disease and monitor response to treatment.

NCT ID: NCT03331991 Recruiting - Influenza Clinical Trials

Prevention of Influenza and Other Wintertime Respiratory Viruses Among Healthcare Professionals in Israel

HCP
Start date: September 28, 2016
Phase: N/A
Study type: Observational

The purpose of the study on the Prevention of Influenza and Other Wintertime Respiratory Viruses among Healthcare Professionals in Israel Effectiveness of Influenza Vaccine in Preventing Influenza Virus Infection, Missed Work, and Patient Exposure: A Prospective Cohort Study of Healthcare Personnel (to be called the Healthcare Personnel or HCP study throughout this Data Security Plan) is to investigate vaccine effectiveness and respiratory illness among healthcare personnel (HCP). This will help to better understand the factors that influence influenza vaccination choice, individual vaccine response, and whether or not the influenza vaccine helps to prevent influenza in HCP.

NCT ID: NCT03328078 Recruiting - Clinical trials for Relapsed Hematologic Malignancy

A Study of CA-4948 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma

Start date: December 28, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This is a multi-center, open-label trial to evaluate the safety, pharmacokinetics (PK), and anti-cancer activity of oral administration of emavusertib (CA-4948) in adult patients with relapsed or refractory (R/R) hematologic malignancies. Part A will evaluate the safety and tolerability of escalating doses of emavusertib as monotherapy (Part A1), and in combination with ibrutinib. In Protocol Version (v) 1.0 through v6.0, patients with Waldenström macroglobulinemia/ lymphoplasmacytic lymphoma (WM/LPL) and chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) were also enrolled at ibrutinib doses of 420 mg (Part A2). Enrollment into Parts A1 and A2 has been closed. Part B will comprise 2 cohorts to assess safety and efficacy of emavusertib in combination with ibrutinib in patients with primary central nervous system lymphoma (PCNSL).

NCT ID: NCT03327207 Recruiting - Clinical trials for Growth Hormone Deficiency

Exploring Interactions Between Growth Hormone and the Microbiome

Start date: November 1, 2017
Phase:
Study type: Observational

The goal of this study is to characterize the microbiome and metabolomics of children with Growth Hormone (GH) deficiency, prior GH treatment initiation and compare it to healthy children

NCT ID: NCT03323697 Recruiting - Depression, Anxiety Clinical Trials

Chinese Herb for the Treatment of Depression and Anxiety Disorders

Start date: August 28, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

Anxiety and depression are currently among the ten most important public health concerns, and in recent years, have reached epidemic proportions. Anxiety is recognized as the main risk factor for many diseases including cardiovascular, metabolic and neuropsychiatric disorders. Current anxiolytic medications have a relatively low success rate (~50%) and are associated with many deleterious side-effects. The investigators aim to investigate the efficacy, safety, and tolerability of a novel herbal treatment on anxiety and depression symptoms in a 6-week double-blind randomized trial.

NCT ID: NCT03317418 Recruiting - Infertility Clinical Trials

Can Pregnancy be Predicted According to ATR-FTIR Spectrophotometry of Incubation Medium of Embryos in IVF

Start date: November 1, 2017
Phase:
Study type: Observational

The aim of this study is to examine the variability of culture media composition based on the ATR-FTIR (Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy) technique on the day of embryo transfer/vitrification. In addition, the study will explore whether variations detected in the culture medium can be linked to embryo quality and the chances of achieving pregnancy.