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NCT ID: NCT00658775 Completed - Clinical trials for Gastroesophageal Reflux Disease (GERD)

Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Start date: February 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy (ie, healing and symptom relief) and safety of Rabeprazole Extended-Release (RAB ER) 50 mg versus Esomeprazole (ESO) 40 mg for the treatment of moderate to severe erosive Gastroesophageal Reflux Disease (eGERD).

NCT ID: NCT00658528 Completed - Clinical trials for Gastroesophageal Reflux Disease (GERD)

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Start date: February 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of Rabeprazole extended release (ER) 50 mg versus Esomeprazole 40 mg for healing and symptomatic relief among subjects with erosive gastroesophageal reflux disease (GERD).

NCT ID: NCT00658515 Completed - Clinical trials for Coronary Heart Disease

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Start date: April 2008
Phase: Phase 3
Study type: Interventional

This study will evaluate the potential of RO4607381 to reduce cardiovascular morbidity and mortality in stable coronary heart disease patients with recent Acute Coronary Syndrome (ACS) and evaluate the long term safety profile of the drug. Eligible patients in stable condition will be randomized to receive either RO4607381 600mg po or placebo po, daily, together with a background of standard medication for ACS (including aspirin, antihypertensives and statins). The anticipated time on study treatment is 2+ years, and the target sample size is 15,600 individuals.

NCT ID: NCT00657930 Completed - Clinical trials for Diabetes Mellitus, Type 2

Observational Study in Type 2 Diabetes Treated by an Intensive Insulin Treatment (ICT) Containing Once Daily Levemir® (Insulin Detemir)

LEONCET2
Start date: March 2008
Phase: N/A
Study type: Observational

This study is conducted in Europe. The aim of this observational study is to gain practical experience with once-daily Levemir administration in type 2 diabetes patients who were previously treated with Insulatard®, Humulin® N (NPH insulins) as basal insulin as part of their ICT under normal clinical practice conditions in Hungary.

NCT ID: NCT00657319 Completed - Clinical trials for Diabetes Mellitus, Type 2

Glycaemic Control and Quality of Care in Type 2 Diabetes on NovoMix® 30 Previously Treated With Mixtard® Insulins

Start date: October 2007
Phase: N/A
Study type: Observational

This observational study is conducted in Europe. The objective of this retrospective observational cohort analysis is to assess the changes of glycaemic control and quality of care in those Type 2 diabetic patients who were previously treated with Mixtard® insulins after 6 months of their switch to analog premix insulin NovoMix® 30 therapy.

NCT ID: NCT00657150 Completed - Clinical trials for Venous Thromboembolism

Dabigatran Etexilate Compared With Enoxaparin in Prevention of Venous Thromboembolism (VTE) Following Total Hip Arthroplasty

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The primary objective of the trial is to demonstrate non-inferiority of 220 mg oral dabigatran etexilate compared to 40 mg subcutaneous enoxaparin administered once daily. Safety and efficacy will be compared between the treatment groups.

NCT ID: NCT00656890 Completed - Ulcerative Colitis Clinical Trials

A Study of MDX-1100 in Subjects With Active Ulcerative Colitis

MDX1100-06
Start date: April 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and tolerability of the MDX-1100 regimen in subjects with active Ulcerative colitis(UC) and determine the response rate at day 57 in patients administered MDX-1100.

NCT ID: NCT00653185 Completed - Diabetes Mellitus Clinical Trials

Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus

Start date: May 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy, safety and tolerability of SYR-472, once daily (QD), in subjects with Type 2 Diabetes Mellitus.

NCT ID: NCT00652522 Completed - Heart Failure Clinical Trials

Atrial Fibrillation Management in Congestive Heart Failure With Ablation

AMICA
Start date: January 2008
Phase: N/A
Study type: Interventional

It is the purpose of the study to show the benefit of the endocardial catheter ablation by pulmonary vein isolation in patients with persistent or longstanding persistent atrial fibrillation, low LVEF and requiring ICD or CRT-D therapy compared to the best medical treatment with antiarrhythmic drugs.

NCT ID: NCT00652470 Completed - Hydrocephalus Clinical Trials

A Study Comparing Two Treatments for Infants With Hydrocephalus

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to study whether infants with triventricular hydrocephalus (TVH) have a better long-term outcome at 5 years when they are treated with a new procedure, endoscopic third ventriculostomy (ETV), than infants treated with the more traditional treatment, insertion of a cerebrospinal fluid (CSF) shunt.