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NCT ID: NCT00862043 Completed - Clinical trials for Pulmonary Hypertension

Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease

SIOVAC
Start date: April 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the clinical efficacy of the mid-term treatment with sildenafil in patients with persistent moderate or severe pulmonary hypertension (PH) after a heart valve intervention.

NCT ID: NCT00861614 Completed - Prostate Cancer Clinical Trials

Study of Immunotherapy to Treat Advanced Prostate Cancer

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if advanced prostate cancer patient s that are treated with radiotherapy (RT) plus ipilimumab live longer that those treated with RT alone

NCT ID: NCT00860366 Completed - Clinical trials for Acute Ischemic Stroke

Efficacy Study of Combined Treatment With Uric Acid and rtPA in Acute Ischemic Stroke

Urico-Ictus
Start date: June 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether the combined treatment with Uric Acid and rtPA is superior to rtPA alone in terms of clinical efficacy in acute ischemic stroke patients treated within the first 4.5 hours of symptoms onset.

NCT ID: NCT00860262 Completed - Hypertension Clinical Trials

Telmisartan and Amlodipine Fixed Dose Combination [FDC] Trial for the Treatment of Severe Hypertension

Start date: March 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to demonstrate that following eight weeks of treatment the FDC of telmisartan 80 mg plus amlodipine 10 mg (T80/A10) is superior as first line therapy in reducing mean seated trough cuff Systolic Blood Pressure [SBP] compared to the monotherapies of telmisartan 80 mg (T80) and amlodipine 10 mg (A10) in patients with severe hypertension. A key secondary objective is to identify the duration of treatment required to demonstrate the superiority of the FDC over both of the monotherapies.

NCT ID: NCT00858871 Completed - Clinical trials for Hepato Cellular Carcinoma (HCC)

First Line Hepato Cellular Carcinoma (HCC)

BRISK FL
Start date: May 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.

NCT ID: NCT00858650 Completed - Clinical trials for Testosterone Deficiency

Registry of Hypogonadism in Men

RHyMe
Start date: March 2009
Phase: N/A
Study type: Observational

The primary objective of the Registry of HYpogonadism in MEn (RHYME) is to establish and maintain a large, multi-national prospective registry of male patients who have been diagnosed with male hypogonadism (HG), also known as androgen deficiency or testosterone deficiency.

NCT ID: NCT00857584 Completed - Bipolar Disorder Clinical Trials

Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapy

Start date: May 2009
Phase: Phase 3
Study type: Interventional

Prospective, open-label, controlled (active comparator), randomized study of 8 weeks follow-up for the evaluation of the efficacy of extended release quetiapine (quetiapine XR) versus Sertraline in addition to previous mood stabilizer treatment (lithium or valproate at stable and clinically therapeutic blood levels) in the treatment of the adult bipolar depression. This multicentric study will be featured in two sites in Spain.

NCT ID: NCT00856986 Completed - Clinical trials for Diabetes Mellitus, Type 2

The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes

Start date: March 2009
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe and North America. The aim of this clinical trial is to assess and compare the effect of insulin detemir in combination with liraglutide and metformin versus liraglutide and metformin in subjects with type 2 diabetes. Subjects will continue their own pre-trial metformin treatment during the trial.

NCT ID: NCT00856544 Completed - Clinical trials for Arthritis, Rheumatoid

A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications

Start date: May 2009
Phase: Phase 3
Study type: Interventional

This Phase 3 study is intended to provide evidence that CP-690,550 dosed 5 mg BID and 10 mg BID is safe and effective when used in combination with a variety of traditional disease modifying antirheumatic drugs in adult patients with rheumatoid arthritis. It is intended to confirm the benefits of CP-690,550 in improving signs and symptoms and physical function that were observed in the Phase 2 rheumatoid arthritis studies.

NCT ID: NCT00856375 Completed - Colorectal Cancer Clinical Trials

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Start date: December 2008
Phase: Phase 2
Study type: Interventional

This study will evaluate whether NKTR-102, an investigational drug has an anti-tumor effect in patients with colorectal cancer. This study will also evaluate how the safety and anti-tumor activity of NKTR-102 compares with irinotecan, a cancer drug that is approved for use in the US for treatment of patients with certain types of colorectal cancer.