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NCT ID: NCT06077539 Recruiting - Clinical trials for Anesthesia Emergence Delirium

Dexmedetomidine Versus Ketamine Versus Magnesium Sulfate for the Prevention of Emergence Agitation Following Sevoflurane Induced Anesthesia in Cardiac Catheterization in Pediatrics

Start date: September 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Emergence agitation (EA) is a post-operative behavioral disturbance was first reported in early 1960s. EA is a term used to describe non purposeful restlessness and agitation, thrashing, crying or moaning, disorientation and incoherence during early stage of recovering from general anesthesia in children, especially those receiving sevoflurane. Generally, the incidence of EA following sevoflurane anesthesia varies from 10% to 66% and is more common in pre-school children. EA is generally short lived without obvious aftereffect. However, it still accompanies with risk of self-injury, and requires extra nursing care, which may delay the discharge and increase the cost of medical care Emergence agitation is diagnosed by a final composite score of greater than or equal to 10 on the Pediatric Anesthesia Emergence Delirium Scale (PAED).(

NCT ID: NCT06076668 Recruiting - Delirium Clinical Trials

Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium

Start date: October 16, 2023
Phase: N/A
Study type: Interventional

This study aims to compare the effect of dexmedetomidine infusion and oral melatonin on preventing delirium in intensive care unit (ICU) patients.

NCT ID: NCT06074471 Recruiting - Anesthesia Clinical Trials

Motor Sparing Supraclavicular Block

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

This study aims to compare MS-SCBPB and SCBPB in the duration of postoperative analgesia, time to first analgesic request (VAS ≥40 mm), pain scores, motor power, and side effects.

NCT ID: NCT06072534 Recruiting - Emergencies Clinical Trials

Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation

RSI
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Mivacurium can be considered as an optimal choice for muscle relaxation in short duration surgeries, as butyrylcholinesterase can rapidly and reliably degrade this benzylisoquinoline muscle relaxant in vivo. However the histamine release related to a rapid high-dose injection, unsatisfactory intubation conditions and unexpected delay in recovery in patients may be encountered with butyrylcholinesterase deficiency

NCT ID: NCT06071455 Recruiting - Clinical trials for Acceleration of Tooth Movement

The Effect of Platelet-rich Fibrin and Vitamin Dꝫ Injections on Canine Retraction

Start date: May 11, 2023
Phase: N/A
Study type: Interventional

the aim of this study is to assess and compare the effect of PRF and vitamin Dꝫ injection on the rate of canine retraction and to determine the bone thickness changes correlated with the two techniques.

NCT ID: NCT06071364 Recruiting - Clinical trials for Chronic Non-specific Low Back Pain

Morphological Changes in Back Muscles With Low Back Pain Patients

Start date: July 1, 2023
Phase:
Study type: Observational

The purpose of this study is to assess the morphological changes in the lumbar multifidus, Erector spinae and Quadratus lumborum muscles and to investigate whether they are correlated with trunk extensor muscle strength in CNSLBP subjects. and to compare between these morphological changes during rest and contraction and to compare these results with control group. Twenty-nine subjects with CNSLBP and 29 age-matched healthy controls will be assessed by ultrasonography to detect the morphological changes of these muscles during rest and contraction ,and assessed strength of back extensors by hand-held dynamometer, and assessed functional disability by Arabic version of Oswestry disability index . They will be asked to sign the informed consent form.

NCT ID: NCT06070155 Recruiting - Clinical trials for Trace Elements Levels After Breast Cancer Radiotherapy

Effect of Aerobic Exercises on Trace Elements in Post-menopausal Women After Radiotherapy

Start date: October 2023
Phase: N/A
Study type: Interventional

This study will be conducted on 28 participants who are survivors of breast cancer and underwent radiotherapy. The purpose of the current study is to investigate the effect of aerobic exercises on quality of life and serum levels of Zinc, Copper and iron in post-menopausal women who received radiotherapy after surviving breast cancer.

NCT ID: NCT06069986 Recruiting - Clinical trials for Coronary Artery Disease

On-pump Versus Off-pump Coronary Artery Bypass Grafting , Short Term Outcomes , Sohag Experience

Start date: July 10, 2023
Phase: N/A
Study type: Interventional

Coronary artery disease (CAD) and its sequlae, such as myocardial infarction, arrhythmia and heart failure, are among the leading causes of death around the world . the durable role of coronary artery bypass grafting (CABG) in the treatment of CAD has long been shown. Coronary artery bypass grafting (CABG) is a commonly performed surgical procedure for patients with coronary artery disease (CAD), CABG can be performed using either the on-pump or off-pump technique, each with its own advantages and limitations. On-pump CABG involves the use of CPB which as agold standard for surgical coronary revascularization has led toexcellent results in mortality and complications. On-pump CABG allows the surgeon to temporarily stop the heart and provide perfusion and oxygenation to the body. This technique provides a bloodless and motionless operative field, allowing for precise graft anastomosis. However, the use of CPB is associated with deleterious effects as systemic inflammatory response, hemodilution, and organ dysfunction as dysrhythmia and neurocognitive problems. These factors may adversely affect patients lives specially those with impaired EF, who already have compromised cardiovascular function. Another technique for CABG is on-pump beating heart CABG (ONBH-CABG) surgery that is relatively novel hybrid approach to coronary artery grafting which aims to stabilize hemodynamic parameters during the operative period. This has specific benefits such as reduced preload alongside the afterload which decreases the oxygen demand of the myocardial tissue

NCT ID: NCT06068686 Recruiting - Type 2 Diabetes Clinical Trials

Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of vildagliptin on copeptin in comparison to glimepiride, and whether copeptin could be used as a marker for the efficacy of vildagliptin in type 2 diabetes mellitus patients, and how copeptin correlates with other diabetic and cardiac markers.

NCT ID: NCT06067724 Recruiting - Stroke Clinical Trials

Effect of Pelvic Control Exercises in Stroke

Start date: May 20, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the combined effect of pelvic and trunk control exercises on muscle performance of affected upper extremity in stroke patients.