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NCT ID: NCT04805281 Recruiting - Clinical trials for Endodontically Treated Teeth

Wear Behavior of Milled Posterior Crowns Fabricated From the New Monolithic Zirconia 5Y-TZP/3Y-TZP Compared to Lithium Disilicate

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

In-vitro studies do not represent the actual masticatory environment and cannot simulate the intricate chewing pattern. Hence, there is a need for an in vivo study evaluating the wear potential of the newly introduced strength - color gradient multilayered zirconia IPS e.max ZirCAD Prime (5Y-TZP/3Y-TZP) and compare it to Lithium Disilicate IPS e.max CAD which has proven to have favorable wear patterns.

NCT ID: NCT04798118 Recruiting - Asthma Clinical Trials

Role of Toilet Bronchoscopy in RICU

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Toilet bronchoscopy is a potentially therapeutic intervention to aspirate retained secretions within the endotracheal tube and airways and revert atelectasis. Aspiration of airway secretions is the most common indication to perform a therapeutic bronchoscopy in the intensive care unit (ICU) . Toilet bronchoscopy is particularly beneficial when retained secretions are visible during the procedure and when air-bronchograms are not present at the chest radiograph. It is also beneficial when there is an indication to reverse lobar atelectasis, rather than simply to remove accumulated mucus. Toilet bronchoscopy is used in lobar and complete lung collapse in mechanically ventilated patients who fail to respond to treatments such as physiotherapy or recruitment manoeuvres. The success rates (defined as radiographic improvement on chest X-ray [CXR] or an improved PaO2/PAO2 ratio) in the ICU patient population had. Patients with acute hypoxaemic respiratory failure may already be on non-invasive ventilation (NIV), or require NIV preemptively for Fiberoptic Bronchoscopy (FB). These patients should be considered high risk for requiring intubation post-procedure; therefore, Fiberoptic Bronchoscopy should be performed by an experienced operator in a setting allowing facilities to safely secure the airways. NIV with early therapeutic FB rather than mechanical ventilation can help avoid intubation and reduce tracheostomy rate. Hospital mortality, duration of ventilation, and hospital stay remain similar

NCT ID: NCT04793763 Recruiting - Chronic Neck Pain Clinical Trials

Comparing the Effect of Deep Neck Flexors Versus MCkenice Exercises on Cervical Functions

McKENICE
Start date: February 27, 2021
Phase: N/A
Study type: Interventional

Physical Therapy rehabilitation programs could involve Manual procedures, stretching, traction, massage, electrotherapy, thermal agents, ultrasound, education and general exercise..In the recovery of patients with neck pain, exercise is one of the most commonly used modalities to gain muscle strength, endurance, and flexibility in order to recover damaged muscles and to maintain regular life activities.. Neck pain management exercise programs vary in terms of length, training frequency, intensity, and mode of exercise. .

NCT ID: NCT04791930 Recruiting - Clinical trials for Vertigo Labyrinthine

Evaluation of Vestibular Function in Patients With C.S.O.M: Safe Type

Start date: October 28, 2021
Phase:
Study type: Observational

To evaluate the function of vestibular system in patients with chronic suppurative otitis media safe type.

NCT ID: NCT04790383 Recruiting - Caries,Dental Clinical Trials

Clinical Performance of Advanced Self- Adhesivee Resin Composite Hybrid Restorations.

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Clinical performance according to modified USPHS criteria of advanced self-Adhesive resin composite hybrid restorations is evaluated for 1 year versus conventional resin composite restorations in posterior teeth.

NCT ID: NCT04782310 Recruiting - Postoperative Pain Clinical Trials

Duloxetine vs Pregabalin for Thoracotomy Pain

Start date: March 10, 2021
Phase: Phase 4
Study type: Interventional

This study investigates the effects of preoperative use of oral combination of duloxetine and Pregabalin in comparison with preoperative oral Pregabalin only in treatment of acute postoperative and prevention of chronic pain following thoracotomy surgeries.

NCT ID: NCT04781751 Recruiting - Pain, Neuropathic Clinical Trials

Ultrasonographic Insulin Versus Dexamethasone Injection With Local Anestheticss in Diabetic Patients With Mild to Moderate Median Nerve Entrapement Neuropathy .

Start date: February 28, 2021
Phase: N/A
Study type: Interventional

Insulin injection in carpal tunnel compared with dexamethsone in diabetic patients

NCT ID: NCT04780854 Recruiting - Clinical trials for Chemotherapy-induced Peripheral Neuropathy

Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)

Start date: November 3, 2020
Phase: Phase 2
Study type: Interventional

Chemotherapy cause many adverse events including induction of peripheral neuropathy. Metformin, the AMPK activator, was found to have protective effect against chemotherapy induced peripheral neuropathy in mouse model and in clinical trials as well. There are different hypothesized mechanisms through which metformin does the protective effect. Such as enhancing mitochondrial activity, reduction of ROS and nitric oxide and activation of AMPK.

NCT ID: NCT04780360 Recruiting - Clinical trials for The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing

Cyanoacrylate Tissue Adhesives Versus Silk Suture at the Palatal Donor Site of Sub Epithelial Connective Tissue Graft

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Subepithelial connective tissue grafts (CTG) are considered the gold standard procedure with proven clinical success when it comes to gingival augmentation aims to to improve periodontal health, which can enhance the long-term prognosis of teeth by obtaining soft tissue coverage of exposed root surfaces and/or augmentation the dimensions of gingival tissue. The procedure require harvesting tissue from a the palate, which increases the complexity of the procedure and patient discomfort. Complications after harvesting a graft would be pain, inflammation, bleeding, flap necrosis and infection in the donor site.

NCT ID: NCT04779463 Recruiting - Clinical trials for Weaning From Mechanical Ventilation

Role of Ultrasound Assessment of Parasternal Intercostal Muscle Thickness During Weaning From Mechanical Ventilation

Start date: June 1, 2020
Phase:
Study type: Observational

Assessment of the the parasternal intercostal muscles thickness by the ultrasonography as a weaning predictor of the mechanically ventilated patients