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NCT ID: NCT00116038 Completed - Osteoarthritis Clinical Trials

A Comparison of Two Metal Surface Finishes on Femoral Components in Hip Arthroplasty

Start date: January 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to compare metal surface finishes (proximal-coated titanium surface versus mid-coated titanium surface) on femoral components in hip arthroplasty.

NCT ID: NCT00116025 Completed - Healthy Subjects Clinical Trials

Pharmacokinetics of Ghrelin

Start date: March 2005
Phase: N/A
Study type: Interventional

The main purpose of this study is to determine the half life of the hormone "ghrelin" in the human body. Other purposes are to investigate the effect of ghrelin on appetite and cardiovascular function.

NCT ID: NCT00115947 Completed - Cirrhosis Clinical Trials

Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites

Start date: December 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to investigate the effect of terlipressin on myocardial perfusion and renal function. Hypothesis: Significant improvement of renal function reflected by: glomerular filtration rate (GFR), renal blood flow (RBF), excretion of salt and metabolites in the urine and related hormones and peptides in the blood. No effect on the systolic function of the heart.

NCT ID: NCT00115791 Completed - Atrial Fibrillation Clinical Trials

Study to Determine the Response and Effectiveness of RSD1235 in Subjects With Atrial Fibrillation or Atrial Flutter

Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the effectiveness of RSD1235 compared with placebo, in the conversion of atrial fibrillation or atrial flutter to sinus rhythm.

NCT ID: NCT00115635 Completed - Prostate Cancer Clinical Trials

Docetaxel and Gemcitabine in Hormonal Refractory Metastatic Prostate Cancer

Start date: March 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of the study is to determine the optimal dose of the combination of docetaxel and gemcitabine in patients with hormone refractory prostate cancer, and evaluate this dose with respect to efficacy and toxicity in a phase II trial.

NCT ID: NCT00115102 Completed - Odontalgia Clinical Trials

Sensory Examination and Pharmacological Modulation of Oral Hyperexcitability in Patients With Atypical Odontalgia and Matched Healthy Controls

Start date: March 2004
Phase: Phase 4
Study type: Interventional

This project examines experimental pain and chronic pain in the mouth, specifically the condition called atypical odontalgia (AO:atypical toothpain). In 16 patients with AO and 16 healthy persons, capsaicin (chili-pepper) is applied to the gingiva to cause pain. This pain is evaluated by the participants. In three sessions, 3 different medications are tested for effect on the pain. The medications are fentanyl, S-ketamine and placebo-treatment (saline). The aim is to know more about pain mechanisms in AO in order to develop an effective treatment.

NCT ID: NCT00114842 Completed - Colorectal Cancer Clinical Trials

Magnetic Resonance (MR) Colonography With Fecal Tagging

Start date: March 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if MR colonography with fecal tagging is better using air or water for distension of the colon. Patients referred to colonoscopy are offered MR colonography before colonoscopy. Two days before colonography, patients ingest a 200 ml Barium sulfate solution 2% four times a day, which will render fecal masses "invisible" on the following MR colonography. Air or water (randomised trial) is used for distension of the colon. The examinations are evaluated by two independent blinded readers.

NCT ID: NCT00113906 Completed - Fatigue Clinical Trials

Melatonin Treatment After Laparoscopic Cholecystectomy

Start date: March 2005
Phase: Phase 2/Phase 3
Study type: Interventional

Circadian disturbances occur after surgery. A double blinded, placebo controlled randomized clinical trial was made to investigate effects of melatonin on postoperative fatigue, sleep disturbances and general wellbeing.

NCT ID: NCT00113308 Completed - Clinical trials for Arthritis, Rheumatoid

COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis

Start date: June 2005
Phase: Phase 3
Study type: Interventional

This study is being conducted to find out if an investigational drug called GW406381 can help people with rheumatoid arthritis.

NCT ID: NCT00110877 Completed - HIV Infection Clinical Trials

TMC114-C214: Trial of TMC114 Administered With Low Dose Ritonavir (RTV) in HIV-1 Infected Treatment Experienced Patients

Start date: April 2005
Phase: Phase 3
Study type: Interventional

Study TMC114-C214 is a randomized, controlled, open-label trial to compare the efficacy, safety and tolerability of TMC114 boosted with low dose ritonavir (RTV) versus Kaletra (LPV)/RTV in lopinavir-naïve treatment-experienced HIV-1 infected patients.