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NCT ID: NCT00113308 Completed - Clinical trials for Arthritis, Rheumatoid

COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis

Start date: June 2005
Phase: Phase 3
Study type: Interventional

This study is being conducted to find out if an investigational drug called GW406381 can help people with rheumatoid arthritis.

NCT ID: NCT00111670 Completed - Clinical trials for Diabetes Mellitus Type 2

A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes

Start date: June 2005
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy, safety and tolerability of DPP-IV Inhibitor compared to placebo in patients with type 2 diabetes. The anticipated time on study treatment is < 3 months and the target sample size is 100-500 individuals.

NCT ID: NCT00111189 Completed - Schizophrenia Clinical Trials

A Study of the Efficacy (Effectiveness) of Paliperidone Palmitate in the Prevention of Recurrence of the Symptoms of Schizophrenia.

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of paliperidone palmitate compared with placebo in the prevention of recurrence of the symptoms of schizophrenia and to assess the safety and tolerability of paliperidone palmitate in patients with stable and symptomatic schizophrenia. The placebo used in this study was a nutritional substance known as 20% Intralipid emulsion given to patients requiring intravenous feedings.

NCT ID: NCT00106574 Completed - Clinical trials for Rheumatoid Arthritis

A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis

Start date: April 2005
Phase: Phase 3
Study type: Interventional

This 2 arm study will compare the safety and efficacy, with regard to reduction of signs and symptoms, of tocilizumab versus placebo in combination with traditional Disease-Modifying Anti-Rheumatic Drug (DMARD) therapy in patients with moderate to severe active rheumatoid arthritis (RA) who have had an inadequate response to current DMARD therapy. Patients will be randomized to receive tocilizumab 8mg/kg iv or placebo iv every 4 weeks, in conjunction with stable DMARD therapy. The anticipated time on study treatment is 3-12 months, and the target sample size is 500+ individuals.

NCT ID: NCT00106470 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Genetic Factors That Influence Chronic Obstructive Pulmonary Disease in Hispanics

Start date: February 2005
Phase: N/A
Study type: Observational

The purpose of this study is to examine genetic factors that influence the development of chronic obstructive pulmonary disease (COPD) in Hispanics, a minority group at high risk for the disease.

NCT ID: NCT00098046 Completed - Herpes Zoster Clinical Trials

Famciclovir Oral Pediatric Formulation in Children 1-12 Years of Age With Varicella Zoster Infection

Start date: July 2005
Phase: Phase 3
Study type: Interventional

Varicella zoster virus causes chickenpox in children and shingles in adults. Chickenpox is usually a self-limiting illness characterized by fever and a rash. Serious complications can include secondary bacterial infections, pneumonia, and encephalitis. Anti-viral treatment is not a standard of care in immunocompetent children, but is recommended whenever a risk of complication exists. This study will evaluate the safety and blood levels of a new formulation of famciclovir in children 1-12 years of age.

NCT ID: NCT00088530 Completed - Clinical trials for Lymphoma, Non-Hodgkin

BBR 2778 for Relapsed, Aggressive Non-Hodgkin's Lymphoma (NHL)

Start date: July 2004
Phase: Phase 3
Study type: Interventional

BBR 2778 is a novel aza-anthracenedione that has activity in experimental tumors and shows reduced potential for cardiotoxicity in animal models. This cytotoxic agent has structural similarities with mitoxantrone as well as general similarities with anthracyclines (such as the tricyclic central quinoid chromophore).

NCT ID: NCT00046176 Completed - HIV Infection Clinical Trials

A HIV Study Of A Fixed-Dose Combination Tablet In Antiretroviral Experienced Patients

Start date: August 26, 2002
Phase: Phase 3
Study type: Interventional

This study is a 48-week study designed to evaluate the safety and efficacy of a fixed-dose combination tablet administered once-a-day versus the individual tablets administered twice-a-day within 3-drug combination regimens in ART (antiretroviral)-experienced HIV-1 infected patients.

NCT ID: NCT00044824 Completed - Asthma Clinical Trials

Efficacy and Safety of Fexofenadine in Mild to Moderate Persistent Asthma

Start date: February 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of fexofenadine 120mg BID compared to placebo in the treatment of subjects with mild to moderate persistent asthma

NCT ID: NCT00044811 Completed - Asthma Clinical Trials

Efficacy and Safety of Fexofenadine in Mild to Moderate Persistent Asthma

Start date: March 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of fexofenadine 120mg BID compared to placebo in the treatment of subjects with mild to moderate persistent asthma