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NCT ID: NCT05802030 Completed - Physical Illness Clinical Trials

Effects of Plyometric Training on University Female Tennis Players' Physical Fitness and Serve Performance

Start date: April 8, 2023
Phase: N/A
Study type: Interventional

The main objective of this study is to examine the effects of upper and lower limb plyometric training on the selected physical fitness and serve performance among university female tennis players in China. The main hypothesis of this study is to evaluate whether there are significant effects of 8 weeks of upper and lower limb plyometric training on selected physical fitness and serve performance among university female tennis players in China.

NCT ID: NCT05801627 Completed - Clinical trials for Diabetes Mellitus, Type 2

SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled by Metformin

Start date: May 6, 2020
Phase: Phase 3
Study type: Interventional

This is the phase 3 randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and long-term safety of SAL067 in T2DM patients uncontrolled by metformin, comprising 24 weeks of double-blind treatment period followed by an open-label treatment period, making up a total of 52 weeks.

NCT ID: NCT05800730 Completed - Healthy Clinical Trials

Westlake Precision Nutrition Study 2 (WePrecision2)

WePrecision2
Start date: May 8, 2023
Phase: N/A
Study type: Interventional

This is a dietary intervention study, which aims to explore different diet challenges for glucose metabolism, including carbohydrates and fasting dietary pattern. Considering the glucose responses to the same food are largely heterogeneous among people, this study integrates the concepts of precision nutrition and N-of-1 design. The study also aims to discover the different impact of the time-restricted diet (TRD) and the energy-restricted diet (ERD) on host metabolic health and our hair growth.

NCT ID: NCT05800418 Completed - Clinical trials for Non-small Cell Lung Cancer

Clinical Study to Compare the Pharmacokinetics and Safety of Ramucirumab Injection With Cyramza ® in Healthy Male Volunteers

Start date: November 4, 2019
Phase: Phase 1
Study type: Interventional

Ramucirumab is a biosimilar drug of CYRAMZA® produced by Chiatai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., LTD. It is a vascular endothelial growth factor receptor 2 (VEGFR-2) antagonist. This single-center, randomized, double-blind, single-dose, parallel phase I study of Ramucirumab injection versus Cyramza ® in healthy male volunteers was designed to evaluate the similarities in pharmacokinetics, tolerance, safety and immunogenicity of Ramucirumab and CYRAMZA®.

NCT ID: NCT05800249 Completed - Clinical trials for Locally Advanced/Metastatic Solid Tumors

PE0116 Injection in Treatment of Patients With Advanced Solid Tumours

Start date: March 8, 2021
Phase: Phase 1
Study type: Interventional

This is a Phase I Clinical Trial to Evaluate the Tolerability, Safety, Pharmacokinetics and Preliminary Antitumor Activity of PE0116 Injection in Treatment of Patients with Advanced Solid Tumor.

NCT ID: NCT05800106 Completed - Clinical trials for Renal Cell Carcinoma

A Bioequivalence Study of Sunitinib Malate Capsules.

Start date: December 4, 2018
Phase: Phase 1
Study type: Interventional

A randomized, open, two-period, two-sequence crossover trial design used to assess the pharmacokinetics and safety of Sunitinib Malate Capsules in healthy volunteers under fed condition, and compare the bioequivalence of Sunitinib Malate Capsules produced by Pfizer and Chia Tai Tianqing Pharmaceutical Group Co., Ltd, respectively.

NCT ID: NCT05799638 Completed - Clinical trials for Heart Failure With Reduced Ejection Fraction

Strategy, Efficacy and Safety of Medication Usage in Heart Failure Patients Who Were Intolerable to GDMT

SEMI
Start date: January 1, 2023
Phase:
Study type: Observational

SEMI trial is a single-center, observational, prospective cohort study. The study enrolled acute heart failure patients admitting to the hospital and intended to accept heart failure therapy. The current guideline recommend ACEI/ARB/ARNI, β blocker, SGLT2i and MRA as the cornerstone medication of HFrEF therapy, but a part patients were intolerable to GDMT because of hypotension, hyperkalemia or renal insufficency. Vericiguat is a new medication therapy choice for the patients with heart failure with reduced ejection fraction (HFrEF), it may has less influence on blood pressure, it is unkonwn about the efficacy and safety of vericiguat in patients who were intolerable to GDMT.

NCT ID: NCT05798767 Completed - Clinical trials for Cognitive Impairment

Preoperative Cognitive Impairment Predicts Postoperative Delirium

Start date: February 1, 2022
Phase:
Study type: Observational

Preoperative cognitive impairment (PCI) may increase the incidence of postoperative delirium (POD), yet screening for cognitive impairment is rarely performed. This study hypothesized that Mini-Cog for preoperative cognitive impairment screening predicts postoperative delirium. Elderly patients (65 years or older) attending Henan Provincial People's Hospital during the trial period who required elective thoracic surgery were recruited into the study.

NCT ID: NCT05798416 Completed - Clinical trials for Acute Mountain Sickness

Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

High altitude (>2400 m) is associated with decreased atmosphere pressure leading to hypoxia which in turn impairs exercise capacity and causes acute mountain sickness (AMS). It is noted that adding CO2 might be beneficial to improve hypoxia and exercise performance at high altitude. However, no device is currently available that can supply a constant low dose of CO2 during free movement at high altitude. We have recently invented a portable device which is small and light enough for supplement of low dose CO2 during field exercise at high altitude.

NCT ID: NCT05797987 Completed - Breast Cancer Clinical Trials

Negative ER Expression Assessed by 18F-FES PET/CT in the MBC With ER-positive Primary Tumor

Start date: December 1, 2022
Phase:
Study type: Observational

To investigate the treatment pattern and efficacy of patients with positive primary ER lesion but negative ER expression in MBC using a novel convenient way of 18F-fluoroestradiol positron emission tomography/computed tomography (18F-FES PET/CT).