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NCT ID: NCT05807542 Completed - Esophagus Cancer Clinical Trials

Neoadjuvant Immunotherapy Combined With Chemotherapy in Patients With Locally Advanced ESCC

Start date: March 1, 2022
Phase: Phase 2
Study type: Interventional

Prediction for pCR After Neoadjuvant Immunotherapy Combined With Chemotherapy Using Single-Cell RNA Sequencing in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma

NCT ID: NCT05807230 Completed - Stroke Clinical Trials

Three-level Network Rehabilitation Model

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The objective of this clinical trial was to compare the effects of different interventions on the recovery of stroke patients. The main question it aims to answer are: whether the intervention mode of integrated Chinese and western medicine is more valuable to implement. Researchers randomly assigned 90 patients to either group A or Group B, 45 in each group. Group A adopted the conventional three-level rehabilitation model; Group B adopted the three-level network rehabilitation model under the medical alliance for rehabilitation treatment with combination of Chinese and Western medicine. Fugl-Meyer motor score was used to assess the patient's motor ability, Berg balance scale was used to assess the patient's balance ability, National Institute of Health stroke scale was used to assess the patient's neurological function, and modified Barthel index was used to assess the patient's ability of daily living.

NCT ID: NCT05806177 Completed - Alzheimer Disease Clinical Trials

Safety, Tolerability and Pharmacokinetics of AD16 Tablets After MAD in Healthy Chinese Adult Subjects

MAD
Start date: May 26, 2020
Phase: Phase 1
Study type: Interventional

This single-center, randomized, placebo-controlled, double-blind, dose-increasing study was designed to evaluate the safety, tolerability, and pharmacokinetics of multiple successive dosing in healthy Chinese adult subjects.In this study, 20 healthy adult subjects were enrolled in a multi-dose study in the 30mg and 40mg groups.

NCT ID: NCT05806086 Completed - Otologic Disease Clinical Trials

Clinical Effect of Panfoxol of Otolaryngological Diseases of Upper Respiratory Tract Infection: A Multicenter Retrospective Observational Study

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Patients with otolaryngological diseases caused by upper respiratory tract infections, including allergic rhinitis, chronic rhinosinusitis, secretory otitis media, and oblate gland hypertrophy, were treated with all drugs from Sun Yat-sen Memorial Hospital of Sun Yat-sen University, the First Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial People's Hospital, and Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2021 to December 2022. According to the treatment methods, the patients were divided into panfosol + conventional treatment group and conventional treatment group for multicenter retrospective analysis.

NCT ID: NCT05805904 Completed - Healthy Volunteers Clinical Trials

A Study to Evaluate the Drug Levels, Safety, and Tolerability of BMS-986278 in Healthy Chinese Participants

Start date: March 29, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the drug levels, safety, and tolerability of BMS-986278 in healthy Chinese participants.

NCT ID: NCT05805267 Completed - Clinical trials for Non Small Cell Lung Cancer

To Evaluate the Correlation Between the Results of Specific Gene Testing and the Efficacy of Targeted Therapy in Patients With NSCLC

Start date: September 20, 2022
Phase:
Study type: Observational

Evaluated the correlation between the qualitative test results of Xiamen Aide the gene test specified by the test reagent and the efficacy of relevant targeted drugs in patients with non-small cell lung cancery, and the research data is used to support the registration and marketing of the assessment reagent

NCT ID: NCT05804539 Completed - Clinical trials for Forward Head Posture

The Recovering Strategy on Forward Head Posture in Chinese Adolescents: Tai Chi and Manual Therapy

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Forward head posture (FHP) is a prevalent deformity that can cause various health issues in adolescents. The programs combining manual therapy (MT) and stability exercises (SE) have shown better effectiveness than stability exercises and home exercises in recovering FHP. However, the effectiveness of the therapy program consisting of Tai Chi and MT for recovering FHP remains unclear. Therefore, this study aimed to investigate the effects of Tai Chi with MT on FHP recovery. Meanwhile, with a particular focus on personalized medicine, we utilized explainable artificial intelligence (XAI) to predict if individuals would reverse to healthy posture based on different interventions.

NCT ID: NCT05804474 Completed - Clinical trials for Intracranial Aneurysm

A Retrospective, Multicenter, Controlled Clinical Trail: to Evaluate the Clinical Efficiency of Intracranial Aneurysm Assistive Software in the Morphological Measurement

Start date: January 1, 2021
Phase:
Study type: Observational

the goal of this clinical trail is to evaluate the clinical efficiency of intracranial aneurysm assistive software in the morphological measurement. The trail is designed as retrospective, multicenter, controlled clinical trail. Collecting probable cases images retrospectively according to inclusion criteria and exclusion criteria strictly. Controlling bias strictly, to make sure the measurement of intracranial aneurysm assistive software is evaluated reliably and precisely. In our trail, six physicions were recruited, containing three neuroradiologists, two radiologists and a residents. Software-assistant planning controls against no software-assisant planning,which aims to evaluate the improvement of morphological measurement efficiency of physicians.

NCT ID: NCT05802628 Completed - Gingivitis Clinical Trials

Salivary Drug Concentration Exploratory Study of Cetylpyridinium Chloride Buccal Tablets

Start date: April 10, 2023
Phase: Phase 4
Study type: Interventional

The study is a single-arm, open-label study to explore the salivary concentration of Cetylpyridinium Chloride Buccal Tablets after single-dose administration in Healthy Subjects

NCT ID: NCT05802212 Completed - Clinical trials for PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Effect of Metformin on Patients With Polycystic Ovary Syndrome

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to understand the effect of Metformin on patients with PCOS.