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NCT ID: NCT05142709 Active, not recruiting - Clinical trials for Metastatic Esophageal Squamous Cell Carcinoma

Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC.

Start date: October 31, 2021
Phase:
Study type: Observational

This study is a multi-center, non-interventional study. Clinicopathologic, treatment , outcome and efficacy data will be collected from medical records in metastatic esophageal squamous cell carcinoma (ESCC) patients.

NCT ID: NCT05142020 Active, not recruiting - Early Pregnancy Clinical Trials

Biomarkers for Early Screening of Gestational Diabetes Mellitus

Start date: January 1, 2022
Phase:
Study type: Observational

Gestational Diabetes Mellitus (GDM) refers to the abnormal glucose metabolism first detected during pregnancy. It is estimated that approximately 7% of pregnant women worldwide and their offspring are affected by GDM. The incidence of GDM in China is as high as 18.9%. A number of studies have shown that GDM complicates 3%-25% of pregnancies and poses serious health and life threats to the mother and child. In fact, due to the lack of physical activity during pregnancy and the decrease of insulin sensitivity compared with non-pregnancy, the optimal time for intervention has long been lost until the diagnosis of GDM in the second trimester. However, it is a pity that no authoritative screening method for GDM in early pregnancy has been established, and the pathogenesis of GDM is still unclear. This study intend to search for biomarkers used for screening of GDM in early pregnancy and explore the pathogenesis of GDM, so as to provide new ideas for prevention measures and treatment targets of GDM.

NCT ID: NCT05141656 Active, not recruiting - Clinical trials for Pancreatic Neoplasms

Construction and Evaluation of China's Advanced Pancreatic Tumor Big Data Center

Start date: August 31, 2019
Phase:
Study type: Observational

This study is a multi-center observational study. The start time for data collection is August 31, 2019. Patients who have been treated at our institution from August 31, 2019, who were diagnosed with pancreatic tumors on or before August 31, 2019 (diagnosed in our hospital or outside hospitals) would all meet the inclusion conditions of the study and be considered enrollment. Patients' baseline and treatment data will be collected under informed concent. The combination of medical big data governance and the leading technology of the big data platform uses real world data to improve the quality and efficiency of pancreatic tumor diagnosis, treatment and scientific research.

NCT ID: NCT05141565 Active, not recruiting - Depression Clinical Trials

The Kunshan Elderly Health Study

KEHS
Start date: May 17, 2021
Phase:
Study type: Observational

The Kunshan Elderly Health Study (KEHS) is a community-based prospective cohort study of chronic disease, mortality and associated factors among elderly adults in Kunshan, Eastern China.

NCT ID: NCT05141422 Active, not recruiting - Clinical trials for Human Immunodeficiency Virus Infection

A Drug-drug Interaction Study of SHR2150 on Healthy Chinese Volunteers

Start date: December 13, 2021
Phase: Phase 1
Study type: Interventional

The study is a single-centre, open-label, fixed-sequence, self-controlled clinical trial. It is planned to enroll 20 healthy adult subjects. Subjects will take SHR2150 on Day 1 and Day 21, and take efavirenz from Day 7 to Day 26.

NCT ID: NCT05136456 Active, not recruiting - Clinical trials for Primary Membranous Nephropathy

Evaluate the Efficacy and Safety of SHR1459 Tablets in Patients With Primary Membranous Nephropathy

Start date: December 15, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of SHR1459 tablets in patients with primary membranous nephropathy.

NCT ID: NCT05134948 Active, not recruiting - Clinical trials for Advanced Solid Tumors

A Study to Assess Relatlimab and Nivolumab Fixed-dose Combination in Chinese Participants With Advanced Solid Tumors

RELATIVITY 059
Start date: November 30, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the safety, drug levels, immunogenicity and preliminary efficacy of BMS-986213 (nivolumab-relatlimab fixed-dose combination) in Chinese participants with advanced solid tumors.

NCT ID: NCT05133492 Active, not recruiting - Clinical trials for Abdominal Aortic Aneurysm

First In Human Study for Small to Medium-sized Abdominal Aortic Aneurysm (AAA)

AAA
Start date: June 24, 2019
Phase: N/A
Study type: Interventional

This is a first in human study to evaluate the safety and clinical utility of an investigational medical device called the Nectero EAST System to treat Abdominal Aortic Aneurysms or AAA.

NCT ID: NCT05132790 Active, not recruiting - Breast Cancer Clinical Trials

Breast Cancer Study of Stereotactic Body Radiation Therapy (SBRT) Combined Neoadjuvant Treatment

Start date: September 25, 2023
Phase: N/A
Study type: Interventional

The study is being conducted to evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) combined neoadjuvant treatment for patients with triple-negative and hormone receptor-positive, HER2-negative breast cancer

NCT ID: NCT05132075 Active, not recruiting - Clinical trials for Non-Small Cell Lung Cancer

Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

KontRASt-02
Start date: June 15, 2022
Phase: Phase 3
Study type: Interventional

This is a phase III randomized open label study designed to compare JDQ443 as monotherapy to docetaxel in participants with advanced non-small cell lung cancer (NSCLC) harboring a KRAS G12C mutation who have been previously treated with a platinum-based chemotherapy and immune checkpoint inhibitor therapy either in sequence or in combination.