There are about 36818 clinical studies being (or have been) conducted in China. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
This multicenter, randomized, double-blind study will evaluate the safety and efficacy of PM8002 in combination with Nab-Paclitaxel compared with placebo combined with Nab-Paclitaxel as first-line treatment in inoperable locally advanced/metastatic triple-negative breast cancer(TNBC)
A Randomized controlled double-blind clinical study on the effectiveness and safety of probiotic formula in Autistic children with gastrointestinal symptoms.
Patients with primary liver cancer (PLC) experience a range of symptoms in the early postoperative period. Symptoms include cancer-related symptoms and adverse effects of treatment. Exploring the core symptoms and their dynamics in the early post-hepatectomy patients may help provide better symptom management programs. The purpose of this study was to identify the core symptoms in early post-hepatectomy patients and to explore the trajectory of their dynamics. During the period from March 2021 to September 2022, a total of 281 patients diagnosed with PLC and undergoing radical curative surgery were recruited from the hepatobiliary surgery departments of two hospitals in Eastern China, among whom 249 individuals (88.60%) agreed to participate in the study. A comprehensive symptom assessment was administered to the patients 1-2 days after surgery (T1) and 1-2 days before discharge (T2). Network analysis was used to identify core symptoms in early post-hepatectomy patients based on symptom severity.
This study is to explore the effects of unilateral, bilateral and combined resistance training on the serve speed and accuracy of amateur youth tennis players in China. The subjects were young male tennis players aged 16-20 years from four universities in Gansu Province. The experiment was divided into control group (CG), experiment group 1 (EG1-unilateral group), experiment group 2 (EG2-bilateral group) and experiment group 3 (EG3-combined group). Used to compare the effects of different forms of resistance training on serve speed and accuracy. Previous studies have shown that unilateral and bilateral resistance training can effectively improve strength, power, and speed in athletes (Speirs, et al., 2016; Davo, Jimenez, & Solana,. , 2018), there is still controversy when comparing the advantages and disadvantages of two forms of resistance training (Ramirez-Campillo et al., 2015; Donab and Wall. The results of this study will be expected to be updated in 2022. Unilateral resistance training, bilateral resistance training, and combined unilateral and bilateral resistance training were used as intervention models in this study. Based on the literature review, the training frequency of this experiment was arranged as 2 times/week, and the total training time was 6 weeks, with a fixed duration of each training session. Each training session lasted a maximum of 60 minutes. In this experiment, the interval between the two weekly training sessions was at least 24 h to prevent subjects from being in a fatigued state in the relevant muscle groups of the body and affecting the experimental level.
A Translational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes associated with Differential Outcomes that may Support Future Development of Personalised Treatment Strategies in Chinese Population
Stimulator of interferon gene (STING) protein plays a vital role in the immune surveillance of tumor microenvironment. Monitoring STING expression in tumors benefits the relevant STING therapy. This study will investigate the safety, biodistribution and potential usefulness of a novel 68Ga-labeled agonist ([68Ga]Ga-Sa-DABI-4) for noninvasive positron emission tomography (PET) imaging of STING expression in the tumor microenvironment.
99mTc-QULIC-5-P1 is a new radiotracer targeting PSMA, which is promising as an excellent imaging agent applicable to PSMA positive prostate cancer. This study will investigate the safety, biodistribution and potential usefulness of 99mTc-QULIC-5-P1 SPECT imaging for the diagnosis of lesions in PSMA positive prostate cancer.
The goal of this clinical study is to evaluate the safety and efficacy of stenting for revascularization treatment of chronic middle cerebral artery (MCA) occlusion in patients with chronic MCA occlusion. The main questions it aims to answer are: 1. Whether stenting treatment can improve blood flow restoration in chronic MCA occlusion. 2. If stenting can reduce the rates of reocclusion. 3. How stenting affects the recovery of neurological functions in these patients. Researchers will compare the stenting group, which received stenting revascularization in addition to aspirin treatment, to the control group, which received only aspirin treatment to see if stenting treatment provides superior outcomes in terms of neurological function improvement and safety profile. Participants will: 1. Undergo full cerebral angiography to identify the occlusion site. 2. All participants will be monitored for post-procedure complications and neurological function using the Modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) before and after treatment. 3. Participants will be followed up for three months post-treatment to assess the long-term efficacy and safety of the stenting procedure.
This study is a single-arm, open-label early exploratory clinical trial designed to evaluate the safety, tolerability, and preliminary efficacy of GC012F injection in subjects with refractory GMG. Additionally, the study aims to assess the pharmacokinetic (PK), pharmacodynamic (PD) characteristics, and immunogenicity of GC012F injection in subjects.
This study has established a multidisciplinary rehabilitation team to recruit patients who underwent radical D2 gastrectomy in multiple centers and divided them into a rehabilitation group and a control group. Intervention will be carried out every time the patients come to the hospital for adjuvant chemotherapy and review. The control group uses traditional intervention model, and the rehabilitation group uses combined exercise/nutrition/psychology rehabilitation intervention. This study is expected to promote early recovery after gastric cancer surgery through multidisciplinary rehabilitation intervention, reduce the occurrence of complications, improve patients' tolerance to adjuvant chemotherapy, and improve patients' quality of life, and hope to improve the short-term and long-term outcomes of gastric cancer patients.