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NCT ID: NCT00294658 Active, not recruiting - Myasthenia Gravis Clinical Trials

Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to determine if thymectomy combined with prednisone therapy is more beneficial in treating non-thymomatous myasthenia gravis than prednisone therapy alone.

NCT ID: NCT00288236 Completed - Clinical trials for Type 2 Diabetes Mellitus

Study Evaluating Rimonabant Efficacy in Insulin-Treated Diabetic Patients(ARPEGGIO)

Start date: January 2006
Phase: Phase 3
Study type: Interventional

Primary: Effect on HbA1c over 48 weeks in insulin-treated patients with type 2 diabetes Secondary: Effect on glucose, total daily insulin dose, body weight, waist circumference, HDL-cholesterol, triglycerides - Safety, tolerability

NCT ID: NCT00286468 Completed - Diabetes Mellitus Clinical Trials

Study of Alogliptin Combined With Sulfonylurea in Subjects With Type 2 Diabetes Mellitus.

Start date: April 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of alogliptin, once daily (QD), combined with a sulfonylurea in adults with type 2 diabetes mellitus.

NCT ID: NCT00286455 Completed - Diabetes Mellitus Clinical Trials

Efficacy and Safety of Alogliptin in Subjects With Type 2 Diabetes

Start date: February 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of alogliptin, once daily (QD), in adults with type 2 diabetes.

NCT ID: NCT00286442 Completed - Diabetes Mellitus Clinical Trials

Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of alogliptin, once daily (QD), combined with metformin in adults with type 2 diabetes mellitus.

NCT ID: NCT00286429 Completed - Diabetes Mellitus Clinical Trials

Efficacy and Safety Study of Alogliptin and Insulin in the Treatment of Type 2 Diabetes.

Start date: February 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of alogliptin, once daily (QD), taken in combination with insulin for the treatment of Type 2 Diabetes.

NCT ID: NCT00284128 Completed - Hypertension Clinical Trials

AVE7688 in Patients With Mild to Moderate Blood Pressure

RAVEL-1
Start date: December 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective is to assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough diastolic blood pressure at the end of week 12. The secondary objectives are: - To assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough systolic blood pressure at the end of week 12 - To compare the percentages of responders after 12 week of treatment - To evaluate the long term safety and tolerability of AVE 7688 with particular attention to angioedema

NCT ID: NCT00281593 Completed - Hypertension Clinical Trials

Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension

Start date: April 2006
Phase: Phase 3
Study type: Interventional

To identify dose combinations of telmisartan and ramipril that are more effective in reducing diastolic blood pressure than each of the respective monotherapies in patients with Stage I or II hypertension.

NCT ID: NCT00280566 Completed - Bipolar Disorder Clinical Trials

Safety and Maintenance of Effect of Ziprasidone Plus a Mood Stabilizer in Bipolar I Disorder (Manic or Mixed)

Start date: December 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if ziprasidone plus a mood stabilizer will continue to be a safe and effective treatment regimen for adults with Bipolar I Disorder (manic or mixed symptoms) after they have achieved 8 consecutive weeks of symptom improvement on the regimen.

NCT ID: NCT00277693 Recruiting - Hemodialysis Clinical Trials

Cardiovascular Protective Effect of Spironolactone in Hemodialysis

Start date: n/a
Phase: Phase 4
Study type: Interventional

The purpose of the present study is to determine if spironolactone is safe and effective in the treatment of cardiovascular complications in hemodialysis patients.