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NCT ID: NCT01306435 Completed - Osteoarthritis Clinical Trials

Low Power Laser and Exercise in Osteoarthritis of the Knee: a Randomized Clinical Trial

Start date: November 2009
Phase: Phase 2
Study type: Interventional

Indroduction: Knee osteoarthritis (OA) is a painful condition causing disability, weakness and poor quality of live. The results are very consistent about the benefits of laser and exercises to improve pain and function in subjects with knee osteoarthritis Objectives: To investigate the effects of Low Power Laser (LBP) associated with exercise in pain, function, range of motion, muscle strength and quality of life of patients with knee osteoarthritis. Methods: Forty patients of both sexes aged between 50 and 75 years with knee osteoarthritis (grade 2-4) were randomized into two groups: Laser-LBP-active dose of 3J more exercises and Group Placebo-LBP- placebo and exercise. Were evaluated for pain, function, range of motion, muscle strength and quality of life on three occasions: before starting treatment (evaluation 1), 3 weeks after laser application (evaluation 2) and 8 weeks after completion of exercise (evaluation 3). There were 33 physical therapy sessions three times a week, on March 1 and the laser was applied in the other, only the exercises.

NCT ID: NCT01305746 Completed - Clinical trials for Systemic Lupus Erythematosus

A Trial for Subjects With Systemic Lupus Erythematosus Who Have Completed Protocol AN-SLE3321

Start date: April 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of A-623 in subjects with SLE.

NCT ID: NCT01305551 Withdrawn - Type 2 Diabetes Clinical Trials

BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

Start date: March 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to demonstrate the bioequivalence (BE) of Saxagliptin and Metformin from a 5 mg Saxagliptin/500 mg Metformin extended release (XR) fixed dose combination (FDC) tablet relative to 5 mg Onglyza™ and 500 mg Glifage® XR (marketed in Brazil by Merck S.A.) tablets administered together in both the fasted and fed states.

NCT ID: NCT01305408 Completed - Depression Clinical Trials

Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/Day) as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Start date: March 2011
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to determine whether armodafinil treatment, at a dosage of 150 mg/day, is more effective than placebo treatment as adjunctive therapy to mood stabilizers for treatment of adults with major depression associated with bipolar I disorder.

NCT ID: NCT01305018 Suspended - Inflammation Clinical Trials

Branched-chain Amino Acids Supplementation and Resistance Exercise-induced Muscle Damage and Inflammation

Start date: August 2011
Phase: N/A
Study type: Interventional

This study aims to evaluate the effects of branched-chain amino acids (BCAA) supplementation on resistance exercise-induced muscle damage and inflammation.

NCT ID: NCT01304732 Completed - Infections Clinical Trials

Totally Implantable Catheters in Pediatric Hematology-oncology: a Study on Infectious Complications

Start date: January 2011
Phase: N/A
Study type: Observational

This is a retrospective analysis of infection on catheters of pediatric oncology patients.

NCT ID: NCT01304680 Recruiting - Cancer Clinical Trials

Evaluation of Fluid Resuscitation in Children With Cancer With Severe Sepsis / Septic Shock

Start date: January 2011
Phase: N/A
Study type: Observational

Retrospective study to evaluate the characteristics of patients and of fluid resuscitation during intensive care unit hospitalization of patients under septic chock.

NCT ID: NCT01304654 Active, not recruiting - Neoplasms Clinical Trials

ALI/ARDS in Oncologic Pediatric Patients

Start date: January 2011
Phase: N/A
Study type: Observational

Identify pediatric oncologic patients with ALI/ARDS at GRAACC/IOP's Pediatric Intensive Care Unit and evaluate the mechanical ventilation practice in these subjects for a 48mo period.

NCT ID: NCT01304459 Recruiting - Infection Clinical Trials

Vancomycin Serum Concentrations in Pediatric Oncology Patients Under Intensive Care

Start date: January 2011
Phase: N/A
Study type: Observational

Observational protocol to analyse routine vancomycin serum levels of patients under intensive care and to obtain percentage of patients that achieve therapeutic values.

NCT ID: NCT01304225 Recruiting - Clinical trials for Diabetic Retinopathy

Panretinal Photocoagulation for Diabetic Retinopathy With PASCAL Laser

Start date: September 2010
Phase: Phase 3
Study type: Interventional

This study will investigate the clinical efficacy and safety of the PASCAL laser (PAttern SCAn Laser) for diabetic retinopathy. Patients with proliferative or severe nonproliferative retinopathy will be treated with panretinal photocoagulation utilizing different treatment strategies. The investigators believe that using "lower" laser parameters, the clinical response may be equivalent with less adverse effects.