Clinical Trials Logo

Filter by:
NCT ID: NCT01068561 Completed - Clinical trials for Retinitis Pigmentosa

Autologous Bone Marrow-Derived Stem Cells Transplantation For Retinitis Pigmentosa

Start date: May 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the short-term safety of a single intravitreal injection of autologous bone marrow stem cells in patients with retinitis pigmentosa.

NCT ID: NCT01067976 Completed - Breast Cancer Clinical Trials

Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast MRI

Start date: February 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to look at the efficacy (how does it work) and safety of gadobutrol when used for obtaining MR images of both breasts.Women with a recent diagnosis of breast cancer by mammogram (X-ray examination of the breasts) may benefit from MRI of the breasts as MRI may detect additional breast cancers.

NCT ID: NCT01067820 Completed - Clinical trials for Coronary Artery Disease

ApoA-I Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation

ASSURE I
Start date: September 2011
Phase: Phase 2
Study type: Interventional

This study is designed to characterize the early effects of ApoA-I synthesis with RVX000222 on coronary atherosclerotic disease when administered to patients with coronary artery disease and have a low HDL-C level, as assessed by Intravascular Ultrasound (IVUS) in addition to standard background therapy.

NCT ID: NCT01066026 Completed - Wrinkles Clinical Trials

Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds

Start date: July 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study was to assess the safety and efficacy of a new metallic cannula to inject hyaluronic acid for dermal augmentation in the nasolabial folds compared to standard needle.

NCT ID: NCT01065649 Completed - Clinical trials for Gastroesophageal Reflux Disease

Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients

NORGERD
Start date: January 2010
Phase: Phase 3
Study type: Interventional

Patients with nonerosive reflux disease (NERD) are less responsive to standard treatment with proton pump inhibitors. The hypothesis of this study was that nortriptyline in analgesic doses may decrease heartburn perception and its corresponding cortical activity measured by magnetic resonance image. Therefore, the aim of this study was to assess the cortical representation of heartburn in patients with NERD under treatment with nortriptyline and placebo.

NCT ID: NCT01065064 Completed - Clinical trials for Refractive Assessment

Visual Performance After RESTOR Implantation

Start date: January 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the distance, intermediate, and near vision after aspheric multifocal diffractive AcrySof® ReSTOR SN6AD1 intraocular lens (IOL) implantation.

NCT ID: NCT01064791 Completed - Clinical trials for Renal Transplantation

Efficacy, Safety, Tolerability, and Pharmacokinetics of Sotrastaurin Combined With Tacrolimus vs. a Mycophenolic Acid-tacrolimus Regimen in Renal Transplant Patients

Start date: December 2009
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of different doses of sotrastaurin when combined with tacrolimus for the prevention of acute rejection after de novo renal transplantation.

NCT ID: NCT01064414 Completed - Clinical trials for Diabetes Mellitus, Type 2

An Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment

Start date: June 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who have reduced kidney function.

NCT ID: NCT01064401 Completed - Clinical trials for Relapsing-Remitting Multiple Sclerosis

Efficacy and Safety of BIIB019 (Daclizumab High Yield Process) Versus Interferon β 1a in Participants With Relapsing-Remitting Multiple Sclerosis

(DECIDE)
Start date: May 2010
Phase: Phase 3
Study type: Interventional

The primary study objective is to test the superiority of Daclizumab High Yield Process (DAC HYP) compared to interferon β 1a (IFN β-1a) in preventing multiple sclerosis (MS) relapse in participants with relapsing remitting multiple sclerosis. The secondary study objectives are to test the superiority of DAC HYP compared to IFN β-1a in slowing functional decline and disability progression and maintaining quality of life in this participant population.

NCT ID: NCT01064284 Completed - Hemophilia A Clinical Trials

Survey of Inhibitors in Plasma-Product Exposed Toddlers

SIPPET
Start date: January 2010
Phase: Phase 4
Study type: Interventional

The primary objective of the study is to assess the immunogenicity of VWF/FVIII and of rFVIII concentrates by determining the frequency of inhibitor development in previously untreated patients (PUPs) or minimally blood component-treated (MBCTPs) in the first 50 EDs or in the first 3 years from enrollment, whichever occurs first.