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Wrinkles clinical trials

View clinical trials related to Wrinkles.

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NCT ID: NCT05847530 Recruiting - Skin Laxity Clinical Trials

Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions

Start date: May 2024
Phase: N/A
Study type: Interventional

The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.

NCT ID: NCT05730517 Completed - Wrinkles Clinical Trials

The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters

TO-COSKIN-2
Start date: February 13, 2023
Phase: N/A
Study type: Interventional

The aim of the randomized, double-blind, placebo-controlled, one-period effectiveness study is to compare the effects of multiple-dose 16 weeks daily dietary supplementation with 5 g collagen alone or 5 g of collagen in combination with hyaluronic acid on skin in healthy human subjects in comparison to placebo product. The main objective is to show that test products have beneficial effects on dermis density, and also on other skin parameters and to investigate differences in the effects among test products.

NCT ID: NCT05254210 Completed - Wrinkles Clinical Trials

Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device

Start date: September 13, 2021
Phase: N/A
Study type: Interventional

The intended use of the Potenza™ device is to collect clinical data for brow lifting and/or treatment of dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.

NCT ID: NCT05089851 Completed - Wrinkles Clinical Trials

Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines

Start date: August 23, 2020
Phase: N/A
Study type: Interventional

This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and wrinkles, as well as overall skin texture and radiance of the face after 12 weeks of twice-daily use in female subjects ages 35 - 60 as compared to placebo. A total of 29 subjects completed study participation.

NCT ID: NCT05011461 Completed - Wrinkles Clinical Trials

The Effect of Topical Almond Oil vs. Topical Retinol on The Appearance of Facial Wrinkles

Start date: May 17, 2021
Phase: N/A
Study type: Interventional

The purpose of this experiment is to analyze wrinkle severity, the skin barrier and facial pigmentation level after topical almond oil application, compared to the use of topical retinol. Both the almond oil and the 0.5% topical retinol studied is investigational.

NCT ID: NCT04988412 Completed - Wrinkles Clinical Trials

The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters

TO-COSKIN
Start date: October 11, 2021
Phase: N/A
Study type: Interventional

The aim of the randomized, double-blind, placebo-controlled, one-period effectiveness study is to compare the effects of multiple-dose 12 weeks daily dietary supplementation with 10 g collagen alone or 5 g or 10 g of collagen in combination with MSM on skin in healthy human subjects in comparison to placebo product. The main objective is to show that test products have beneficial effects on dermis density, and also on other skin parameters and to investigate differences in the effects among test products.

NCT ID: NCT04545970 Completed - Wrinkles Clinical Trials

A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines

Start date: December 23, 2019
Phase: N/A
Study type: Interventional

This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin after 12 weeks of twice-daily use in female subjects, aged 35-60, compared to placebo. A total of 55 subjects completed study participation which included 33 subjects in the active group and 22 subjects in the placebo group.

NCT ID: NCT03811756 Completed - Wrinkles Clinical Trials

The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

Q10-collagen
Start date: October 15, 2018
Phase: N/A
Study type: Interventional

Placebo controlled double-blind multi-dose comparative study of the effects of coenzyme Q10 and collagen formulation with improved water-solubility in healthy adults. One group (test group) will receive investigational product - test syrup (daily dose 10 mL: fish collagen: 4000 mg, water soluble CoQ10 (Q10Vital®): 50 mg, vitamin C: 80 mg, vitamin A: 920 μg, biotin: 150 μg) and the other (placebo group) placebo syrup without those active ingredients. Participants will test continuous administration of placebo or investigational product for 12 weeks in order to demonstrate and assess multiple-dose effects on skin condition and signs of skin aging.

NCT ID: NCT03803059 Completed - Wrinkles Clinical Trials

Efficacy and Tolerability of SkinPen on Male and Female Subjects' Wrinkles of the Neck

Start date: January 31, 2019
Phase: N/A
Study type: Interventional

This single-center, the clinical trial is being conducted over the course of 90 days followed by 1-month and 6-month post-treatment visits in order to assess the efficacy and tolerability of the Sponsor's SkinPen device when used by men and women with the wrinkles of the neck.

NCT ID: NCT03477825 Completed - Wrinkles Clinical Trials

Pilot Study of Triphala and Rubia Cordifolia on Gut Microbiome and Skin

Start date: March 12, 2018
Phase: N/A
Study type: Interventional

Few studies have assessed the effects of Triphala and Rubia Cordifolia from a skin biophysical perspective. Here, we aim to understand how these herbs can modulate the skin's barrier properties and the gut microbiome.