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NCT ID: NCT00389662 Completed - Healthy Clinical Trials

The Effect of Wearing the 'Nike Free'Shoe on Isokinetic Muscle Strength of Foot and Ankle and on Proprioception.

Start date: November 2006
Phase: N/A
Study type: Interventional

To evaluate the effect of wearing the 'Nike Free'Shoe on isokinetic muscle strength of foot and ankle and on proprioception the following protocol will be used. The test population consists out of students of the physical education department. They will at random be divided in three groups. One group will wear the shoe only for daily activities, the second group will wear the shoes for the warming up part of the sport classes and the control group will not wear the shoe at all. There will be two moments for evaluation: one at the beginning of the study and one after four months, during which the shoe will be used. The isokinetic strength will be measured with an isokinetic device (Biodex) and the proprioception will be evaluated with a force platform (Neurocom Balance Master).

NCT ID: NCT00389220 Completed - Coronary Disease Clinical Trials

Limus Eluted From A Durable Versus ERodable Stent Coating

LEADERS
Start date: November 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the BioMatrix Flex (Biolimus A9-Eluting) stent system with the Cypher SELECT (Sirolimus-Eluting) stent system in a non-inferiority trial.

NCT ID: NCT00389155 Completed - Bladder Cancer Clinical Trials

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Start date: January 2007
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to test an investigational drug, vinflunine (BMS-710485), in combination with gemcitabine in patients with Transitional Cell Carcinoma who cannot be treated with cisplatin. This study will help to determine whether vinflunine in combination with gemcitabine will extend the time period until further growth of the tumor more than gemcitabine alone.

NCT ID: NCT00388960 Completed - Clinical trials for Small Cell Lung Cancer

Study of Amrubicin With or Without Cisplatin Versus Etoposide-cisplatin for Extensive Stage Small Cell Lung Cancer

Start date: November 1, 2006
Phase: Phase 2
Study type: Interventional

The purpose of the study is to document the activity and safety of single agent amrubicin, amrubicin combined with cisplatin, and etoposide combined with cisplatin as first-line treatment in extensive disease small cell lung cancer.

NCT ID: NCT00388726 Completed - Breast Cancer Clinical Trials

E7389 Versus Treatment of Physician's Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

Start date: November 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare Overall Survival (OS), Progression Free Survival (PFS), objective tumor response rate, duration of response, and safety in patients treated with E7389 versus the Treatment of Physician's Choice (TPC) in patients with locally recurrent or metastatic breast cancer.

NCT ID: NCT00386698 Completed - Influenza Clinical Trials

Study to Evaluate Reactogenicity and Immunogenicity of Revaccination With Adjuvanted Influenza Vaccine in Elderly Adults

Start date: October 2006
Phase: Phase 2
Study type: Interventional

Since influenza vaccines are normally administered every year because of the frequent change in their antigenic composition, the safety and immunogenicity profiles of the adjuvanted influenza vaccine need to be re-evaluated after repeated vaccine administration. In this study, subjects enrolled in a previous study will receive a booster dose with the 2006-2007 season's formulations of Fluarix or the adjuvanted vaccine.

NCT ID: NCT00386685 Completed - Breast Neoplasms Clinical Trials

XRP9881 in Combination With Trastuzumab in Metastatic Breast Cancer

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to assess the activity of XRP9881 in combination with trastuzumab. The secondary objectives are safety and pharmacokinetic interaction

NCT ID: NCT00386451 Completed - Neoplasms Clinical Trials

Comparing a Closing System Without a Needle With Positive Pressure to a Heparin Lock With Positive Pressure

Start date: November 2006
Phase: N/A
Study type: Interventional

A prospective randomized study to compare 2 groups: - heparine lock with positive pressure - lock without a needle with positive pressure

NCT ID: NCT00386425 Completed - Severe Sepsis Clinical Trials

Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)

Start date: November 2006
Phase: Phase 2
Study type: Interventional

In this trial, patients with severe sepsis and low protein C levels will receive drotrecogin alfa (activated) at the normal, approved dose and time of administration [24 microgram/kilogram/hour (mcg/kg/hour) for 96 hours] or will receive the normal, approved dose or higher doses than the approved dose for a longer administration time. After the drug administration is complete, the protein C levels from the patients receiving the normal, approved dose will be compared to protein C levels from patients receiving the normal, approved dose or higher dose for a longer duration to determine if the protein C levels improve faster if given higher dose and/or longer administration time. Note: The protocol was amended to remove the option of shorter infusion durations.

NCT ID: NCT00386113 Completed - Influenza Clinical Trials

Study to Evaluate Reactogenicity and Immunogenicity of Revaccination With Adjuvanted Influenza Vaccine in Elderly

Start date: October 16, 2006
Phase: Phase 2
Study type: Interventional

Since influenza vaccines are normally administered every year because of the frequent change in their antigenic composition, the safety and immunogenicity profile of adjuvanted influenza vaccine need to be re-evaluated after repeated vaccine administration. In this study, subjects previously vaccinated with Fluarix or the influenza adjuvanted vaccine, will receive a booster dose with the 2006-2007 season's formulations of either Fluarix or the adjuvanted vaccine.