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NCT ID: NCT00665561 Completed - Clinical trials for Human Immunodeficiency Virus

Prospective Observational Epidemiologic Study of Maraviroc's Safety

POEM
Start date: March 31, 2008
Phase:
Study type: Observational

The study will assess if use of maraviroc along with an optimized background regimen of antiretroviral drugs in usual clinical practice is as safe as using only an optimized regimen of antiretroviral drugs.

NCT ID: NCT00665509 Completed - Influenza Clinical Trials

Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 08/09 Season.

Start date: June 2008
Phase: Phase 3
Study type: Interventional

Influenza (flu) viruses change continuously, therefore also the parts of viruses used in influenza vaccines can vary from year to year. In Europe, manufacturers/marketing holders of these vaccines are required to be involved in ongoing clinical trials and to present the results to the competent authorities each year. The current study is a phase IIIa clinical trial with a commercially available vaccine (Influvac®) supplied in pre filled syringes. It is part of the ongoing clinical trial program for Influvac® and will be done to assess the immunogenicity and safety and tolerability of next season's trivalent influenza subunit vaccine in two groups of healthy subjects: subjects aged >= 18 and <= 60 years and subjects >= 61 years of age (elderly).

NCT ID: NCT00665223 Completed - Clinical trials for Huntington's Disease

A Study of Treatment With Pridopidine (ACR16) in Participants With Huntington's Disease

MermaiHD
Start date: April 24, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if ACR16 is effective and safe in the symptomatic treatment of Huntington's disease.

NCT ID: NCT00663052 Completed - Psoriasis Clinical Trials

Study Evaluating Etanercept for the Treatment of Moderate to Severe Psoriasis

PRISTINE
Start date: June 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of different doses of etanercept for the treatment of moderate to severe psoriasis.

NCT ID: NCT00662831 Completed - Diabetic Foot Ulcer Clinical Trials

Study Of The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients

FEENICS
Start date: April 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the study isto see the effect of Fragmin on the healing of diabetic foot ulcers by determining the number of subjects with ≥50% reduction in ulcer surface area including intact skin healing.

NCT ID: NCT00662649 Completed - Multiple Sclerosis Clinical Trials

Long-term Efficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing-remitting Multiple Sclerosis

Start date: February 2008
Phase: Phase 3
Study type: Interventional

This extension study of was designed to evaluate the long-term safety, tolerability, and efficacy of fingolimod (FTY720) in patients with multiple sclerosis. The Extension study was an extension to the 24-month Core study (CFTY720D2301/NCT00289978).

NCT ID: NCT00661232 Completed - Clinical trials for Coronary Artery Disease

Multicenter Myocardial Viability Trial

Start date: August 11, 2003
Phase:
Study type: Observational

The purpose of this study is to test the hypothesis of whether contrast enhanced Magnetic Resonance Imaging can be used to predict improvement of the wall motion in regions of the heart with abnormal movement following bypass surgery or percutaneous angioplasty in various institutions across three continents.

NCT ID: NCT00660959 Completed - Clinical trials for Hyponatremia With Normal Extracellular Fluid Volume

Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia

Start date: April 2008
Phase: Phase 3
Study type: Interventional

The present study is designed to confirm and extend the observation from previous studies that lixivaptan therapy corrects hyponatremia, in euvolemic subject, including subjects with SIADH.

NCT ID: NCT00660881 Completed - Clinical trials for Systemic Lupus Erythematosus

Open-label Study of Epratuzumab in Serologically-positive Systemic Lupus Erythematosus Patients With Active Disease

Start date: May 2008
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to assess the safety of epratuzumab in patients with SLE.

NCT ID: NCT00660179 Completed - Clinical trials for Pulmonary Arterial Hypertension

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

SERAPHIN
Start date: May 2008
Phase: Phase 3
Study type: Interventional

The AC-055-302/SERAPHIN study will be an event-driven Phase III study, comparing two different doses of macitentan (ACT-064992) (3 and 10 mg) vs placebo in patients with symptomatic PAH. The main study objective is to demonstrate that macitentan (ACT-064992) prolongs time to the first morbidity or mortality event, and to evaluate the benefit/risk profile of macitentan (ACT-064992) in the treatment of patients with symptomatic PAH.