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NCT ID: NCT00855465 Completed - Clinical trials for Pulmonary Hypertension

A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH.

CHEST-1
Start date: February 23, 2009
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the efficacy and safety of different doses of BAY63-2521, given orally for 16 weeks, in patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH).

NCT ID: NCT00855218 Completed - Clinical trials for Carcinoma, Hepatocellular

A Phase II Randomized, Double-blind, Placebo-controlled Study of Sorafenib or Placebo in Combination With Transarterial Chemoembolization (TACE) Performed With DC Bead and Doxorubicin for Intermediate Stage Hepatocellular Carcinoma (HCC).

Start date: March 2009
Phase: Phase 2
Study type: Interventional

This study will look at whether our drug (sorafenib) in combination with chemotherapy delivered directly into your tumor using beads (DC Bead) will slow the progression of the disease. The beads used with the chemotherapy will slowly release the chemotherapy reducing the adverse effects that normally occur with chemotherapy.

NCT ID: NCT00855101 Completed - Healthy Volunteers Clinical Trials

A Pharmacokinetic And Safety Study Of Voriconazole In Healthy Male And Female Adults

Start date: April 2009
Phase: Phase 1
Study type: Interventional

This study is to assess the plasma concentration-time profile of voriconazole in adults receiving 7-day intravenous treatment and 6.5-day oral treatment. This study is also to assess the safety profile of voriconazole during the treatment period.

NCT ID: NCT00854802 Completed - Chronic Hepatitis C Clinical Trials

A Study of Debio 025 (Alisporivir) Combined With Peg-IFNα2a and Ribavirin in Treatment naïve Chronic Hepatitis C Genotype 1 Patients

Start date: January 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare several Debio 025 (alisporivir)/peg-IFNα2a/ribavirin triple therapies with the current standard of care (SOC) in treatment naïve chronic hepatitis C genotype 1 patients.

NCT ID: NCT00854217 Completed - Cardiac Surgery Clinical Trials

Cardioprotective Effects of Endogenous Erythropoietin in Patients Undergoing Coronary Artery Bypass Surgery

Start date: March 2009
Phase: N/A
Study type: Interventional

Several studies have highlighted the cardioprotective effects of acute normovolemic hemodilution during cardiac surgery. The aim of our study is to show that an increase in endogenous erythropoietin (EPO) might explain the cardioprotective effects of acute normovolemic hemodilution against ischemia-reperfusion phenomena.

NCT ID: NCT00853840 Completed - AIDS Clinical Trials

Study To Investigate The Hemodynamic Effects Of Single Dose Vardenafil In Subjects Receiving Maraviroc

Start date: April 2008
Phase: Phase 4
Study type: Interventional

The objective of this study was to estimate the effects of a single dose of vardenafil on the blood pressure (BP) in subjects receiving maraviroc (MVC) (dosed to steady-state) and to assess the safety and tolerability of MVC in subjects receiving a single dose of vardenafil.

NCT ID: NCT00853827 Completed - Clinical trials for Coronary Artery Disease (CAD)

Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients

AQUARIUS
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The study will assess the change in coronary atherosclerotic disease as determined by intravascular ultrasound (IVUS) for aliskiren compared to placebo when given in addition to standard therapy in patients with coronary artery disease (CAD) and a blood pressure in the pre-hypertensive range.

NCT ID: NCT00853658 Completed - Clinical trials for Chronic Heart Failure

Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbi-mortality in Patients With Chronic Heart Failure

ATMOSPHERE
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The study will evaluate the efficacy and safety of both aliskiren monotherapy and aliskiren/enalapril combination therapy as compared to enalapril monotherapy, on morbidity and mortality in patients with chronic heart failure (NYHA Class II - IV.

NCT ID: NCT00853034 Completed - Healthy Clinical Trials

Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects

Start date: October 2006
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the effects of arabinoxylan-oligosaccharides (AXOS) on the colonic metabolism and microbial composition, and to compare these effects with the reference prebiotic fructo-oligosaccharide enriched inulin.

NCT ID: NCT00852813 Completed - Healthy Clinical Trials

Tolerance and Prebiotic Activity of Arabinoxylan-Oligosaccharides in Healthy Subjects

Start date: October 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the tolerance of a higher dose of arabinoxylan-oligosaccharides (AXOS) and their prebiotic activity in healthy subjects.