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NCT ID: NCT00861120 Completed - Clinical trials for Epithelial Ovarian Cancer

Panitumumab and Pegylated Liposomal Doxorubicin for Platinum-Resistant Epithelial Ovarian Cancer With KRAS Wild-type

PaLiDo
Start date: April 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the response rate in platinum-resistant, KRAS wild-type, ovarian cancer patients who are treated with pegylated liposomal doxorubicin (Caelyx®) in combination with biological treatment panitumumab (Vectibix®).

NCT ID: NCT00860730 Completed - Clinical trials for Aortic Valve Replacement

PERCEVAL Pivotal Trial

Start date: January 2009
Phase: N/A
Study type: Interventional

The clinical investigation is designed as a prospective and non-randomised study on a maximum of 150 patients. This study will be conducted at Investigational Centres in the European Community. A minimum number of 8 European Centres will be involved in the clinical investigation. A minimum of 15 patients will be enrolled at each Investigational Centre. The clinical follow-up requires evaluations at discharge (or 30 days if the patient is still hospitalized), 3-6 and 12 months following the procedure.The primary objective of this clinical investigation is to assess the performance of the Perceval S valve at 3-6 months after implantation in high surgical risk patients, who require a surgical intervention to replace the aortic valve.

NCT ID: NCT00860405 Completed - Cardiac Surgery Clinical Trials

Voluven® in Paediatric Patients

Start date: March 2009
Phase: Phase 4
Study type: Interventional

This study will compare the clinical efficacy and safety of Voluven® and Human Albumin during elective open-heart surgery in pediatric patients.

NCT ID: NCT00860288 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes

Start date: February 2009
Phase: Phase 2/Phase 3
Study type: Interventional

This is a 2-3 period parallel group study with an adaptive element in Type 2 diabetes patients receiving vildagliptin as add-on therapy to metformin

NCT ID: NCT00858871 Completed - Clinical trials for Hepato Cellular Carcinoma (HCC)

First Line Hepato Cellular Carcinoma (HCC)

BRISK FL
Start date: May 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.

NCT ID: NCT00857740 Completed - Fibromyalgia Clinical Trials

Influence of Painphysiolgy Education on the Pain Inhibition in Fibromyalgia

Start date: March 2009
Phase: Phase 0
Study type: Interventional

The purpose of this study is to investigate whether education about the neurophysiology of pain is able to improve central pain inhibition in patients with Fibromyalgia.

NCT ID: NCT00857441 Completed - Clinical trials for Coronary Artery Disease

Drug-eluting Balloon in Bifurcations Trial

DEBIUT
Start date: January 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the DEBIUT study is to assess procedural, clinical and angiographic outcomes of: 1. Provisional T-stenting use for dilation the Paclitaxel-eluting PCI-balloon (DiorTM) in comparison to dilation with a standard balloon prior to the implant of the Liberty Bare Metal Stent in bifurcation lesions (with side branch involvement). 2. Comparison of the results above with the results of using a standard balloon prior to provisional T-stenting with the Paclitaxel-eluting stent TaxusTM LibertéTM.

NCT ID: NCT00856986 Completed - Clinical trials for Diabetes Mellitus, Type 2

The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes

Start date: March 2009
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe and North America. The aim of this clinical trial is to assess and compare the effect of insulin detemir in combination with liraglutide and metformin versus liraglutide and metformin in subjects with type 2 diabetes. Subjects will continue their own pre-trial metformin treatment during the trial.

NCT ID: NCT00856856 Completed - Clinical trials for Coronary Artery Disease

ABSORB Clinical Investigation, Cohort B

ABSORB B
Start date: March 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety and performance of the BVS Everolimus Eluting Coronary Stent System (EECSS) in the treatment of patients with a maximum of two de novo native coronary artery lesions located in two different major epicardial vessels. Currently in development at Abbott Vascular. Not available for sale in the United States.

NCT ID: NCT00856375 Completed - Colorectal Cancer Clinical Trials

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Start date: December 2008
Phase: Phase 2
Study type: Interventional

This study will evaluate whether NKTR-102, an investigational drug has an anti-tumor effect in patients with colorectal cancer. This study will also evaluate how the safety and anti-tumor activity of NKTR-102 compares with irinotecan, a cancer drug that is approved for use in the US for treatment of patients with certain types of colorectal cancer.