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NCT ID: NCT00864786 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Multiple Dose Healthy Volunteer Safety Pharmacokinetics Study

Start date: September 2008
Phase: Phase 1
Study type: Interventional

Multiple dose safety and pharmacokinetics in healthy male subjects

NCT ID: NCT00864552 Completed - Hemophilia A Clinical Trials

International PMS Study - KOGENATE Bayer

Start date: December 2002
Phase: N/A
Study type: Observational

To evaluate long-term safety (primarily by recording adverse events including inhibitors), efficacy and patient acceptance of KOGENATE Bayer in home treatment either on prophylaxis or on demand. To evaluate both safety and efficacy with respect to lot variability, in particular regarding lot-groups formulated with or without fix between.

NCT ID: NCT00864266 Completed - Clinical trials for Non Small Cell Lung Carcinoma

Biological Factors Predicting Response to Chemotherapy in Advanced Non Small Cell Lung Cancer

Start date: March 2009
Phase: N/A
Study type: Interventional

The primary aim of the study is to identify a predictive molecular signature for response to chemotherapy, according to WHO criteria, in patients with non-small cell lung cancer by studying the transcriptome (miRNAs and mRNAs) and the single nucleotide polymorphism (SNPs) by using high throughput techniques.

NCT ID: NCT00863746 Completed - Carcinoma Clinical Trials

A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC).

MISSION
Start date: April 2009
Phase: Phase 3
Study type: Interventional

The purpose of the study is to see if sorafenib plus best supportive care (i.e. in addition to the non-cancer treatments patients would normally receive) is an effective treatment for lung cancer compared to best supportive care alone. The safety and tolerability of the two treatment groups will also be compared. The goal of the study is to test the ability of sorafenib to improve survival compared to best supportive care alone.

NCT ID: NCT00863681 Completed - Clinical trials for Hypertension, Pulmonary

BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial Hypertension

PATENT-2
Start date: March 12, 2009
Phase: Phase 3
Study type: Interventional

Patients who have completed the 12 weeks treatment of the PATENT-1 trial (study number 12934) will be asked to participate in this long term extension study with BAY63-2521.

NCT ID: NCT00863655 Completed - Breast Cancer Clinical Trials

Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole

BOLERO-2
Start date: June 2009
Phase: Phase 3
Study type: Interventional

There are no treatments specifically approved after recurrence or progression on a non steroidal aromatase inhibitors (NSAI). In light of the need for new treatment options for postmenopausal women after failure of prior NSAI therapy, the purpose of this Phase III study is to compare efficacy and safety of a treatment with exemestane + everolimus to exemestane + placebo in postmenopausal women with estrogen receptor positive locally advanced or metastatic breast cancer refractory to NSAI.

NCT ID: NCT00862654 Completed - Clinical trials for Scalp Seborrheic Dermatitis

Clobetasol Propionate 0.05% Shampoo in Association With Antifungal Shampoo in Scalp Seborrheic Dermatitis

Escape
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The objective is to assess different treatment regimens with Clobetasol propionate shampoo 0.05% in the treatment of scalp Seborrheic Dermatitis.

NCT ID: NCT00861809 Completed - Gastroparesis Clinical Trials

The Effect of Single Doses of the Motilin Receptor Agonist GSK962040 in Type I Diabetic Patients With Gastroparesis

Start date: June 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the pharmacodynamic effects (gastric emptying), safety, tolerability, and pharmacokinetics of single doses of GSK962040 in Type 1 diabetic patients with gastroparesis.

NCT ID: NCT00861614 Completed - Prostate Cancer Clinical Trials

Study of Immunotherapy to Treat Advanced Prostate Cancer

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if advanced prostate cancer patient s that are treated with radiotherapy (RT) plus ipilimumab live longer that those treated with RT alone

NCT ID: NCT00861458 Completed - Hepatitis C Virus Clinical Trials

Bioavailability Study Of PF-00868554 Administered As 3x250mg Oral Tablets (Wet Granulate, 3x250mg Oral Tablets (Dry Granulate) And 750mg Solution Under Fed State

Start date: April 2009
Phase: Phase 1
Study type: Interventional

This study will test two different formulations. The results will be used to select formulation for phase 3.