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NCT ID: NCT00225277 Completed - Diabetes Mellitus Clinical Trials

Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus

PERISCOPE
Start date: July 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study was to determine the efficacy of pioglitazone, once daily (QD), compared to glimepiride on atherosclerotic disease measured by intravascular ultrasound.

NCT ID: NCT00225017 Completed - HIV Infection Clinical Trials

Switch to Atazanavir and Brachial Artery Reactivity (SABAR) Study

SABAR
Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the change in brachial artery reactivity in HIV-infected subjects with elevated lipid levels who are switched to an atazanavir containing antiretroviral regimen

NCT ID: NCT00220740 Completed - Clinical trials for Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

ICE
Start date: April 2004
Phase: Phase 3
Study type: Interventional

The intent of this study is to demonstrate the efficacy and safety of Immune Globulin Intravenous (Human), 10% Caprylate/Chromatography Purified (IGIV-C) in newly or previously diagnosed CIDP subjects. Eight courses of treatment with either placebo or IGIV-C will occur every 3 weeks. Neurological function will be measured by Inflammatory Neuropathy Cause and Treatment (INCAT) scores. Patients who deteriorate or show no improvement between day 16 and month 6 will receive the alternate study drug for an additional 6 months.

NCT ID: NCT00219622 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

A Phase 2 Study of the Safety and Efficacy of a Tofimilast in Adult Patients With Chronic Obstructive Pulmonary Disease

Start date: May 2004
Phase: Phase 2
Study type: Interventional

This an initial proof of concept, phase to study to assess the safety and efficacy of tofimilast for the chronic maintenance treatment of adults with Chronic Obstructive Pulmonary Disease

NCT ID: NCT00219141 Completed - Hypertension Clinical Trials

Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension

ALLAY
Start date: October 2005
Phase: Phase 3
Study type: Interventional

To compare the efficacy and safety of aliskiren in combination with losartan compared to losartan on the regression of the increased size of the left ventricle in overweight patients with high blood pressure.

NCT ID: NCT00216190 Completed - Clinical trials for Mechanically Ventilated and Intubated Subjects

A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation

Start date: March 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of dexmedetomidine in ICU subjects who are initially intubated, mechanically ventilated and require sedation for beyond 24 hours.

NCT ID: NCT00214565 Terminated - Clinical trials for Diabetes Mellitus, Type 2

GALLANT 6 Tesaglitazar vs. Pioglitazone

Start date: August 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized, double-blind, multi-center, active-controlled (pioglitazone) study of tesaglitazar (0.5 mg and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 3-week enrollment period, 6 week placebo single blind run in period followed by a 24-week double blind treatment period and a 3-week follow-up period.

NCT ID: NCT00210639 Completed - Clinical trials for Musculoskeletal Diseases

A Study of Incidence of Musculoskeletal Disorders in Children Who Have Received Levofloxacin or a Standard Non-Fluoroquinolone Therapy for Acute Bacterial Infection

Start date: August 2002
Phase: Phase 3
Study type: Observational

The purpose of this study is to assess the long-term safety of levofloxacin administered to children as therapy for acute bacterial infection.

NCT ID: NCT00207688 Completed - Ulcerative Colitis Clinical Trials

A Long Term Safety Study of Infliximab (Remicade) in in Ulcerative Colitis Patients

Start date: August 31, 2004
Phase:
Study type: Observational

The purpose of this study is to evaluate long-term safety information of infliximab in patients who have participated in infliximab clinical studies in ulcerative colitis.

NCT ID: NCT00206700 Terminated - Crohn Disease Clinical Trials

Open-label Trial of Leukine in Active Crohn's Disease

Start date: February 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to establish a safety profile sargramostim administered in 8 week cycles to adult patients with active Crohn's disease.