Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease — DEFINE-DM

Coronary Artery Stenosis Clinical Trial

Official title:
A Comparison of Imaging- and Physiology-Guided State-of-the-Art Percutaneous Coronary Intervention and Coronary-Artery Bypass Grafting in Patients With Diabetes and Three-Vessel Coronary Artery Disease: DEFINE-DM Trial (Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease)

Status Not yet recruiting

Clinical Trial Summary

The objective of this randomized study was to compare outcomes of imaging-and physiology-guided state-of-the-art Percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) in patients with diabetes and multivessel coronary artery disease(CAD) with left anterior descending(LAD) involvement.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05831085
Study type	Interventional
Source	Asan Medical Center
Contact	Jung-hee Ham, Project manager
Phone	82-2-3010-4728
Email	cvcrc5@amc.seoul.kr
Status	Not yet recruiting
Phase	Phase 4
Start date	February 20, 2024
Completion date	December 2027

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05133843` - Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis	N/A
Completed	`NCT01205776` - EXCEL Clinical Trial	N/A
Completed	`NCT01182428` - XIENCE V: SPIRIT WOMEN Sub-study	Phase 4
Completed	`NCT00739466` - Biorest Liposomal Alendronate With Stenting sTudy (BLAST)	Phase 2
Completed	`NCT01332591` - Multivessel Disease Diagnosed at the Time of PPCI for STEMI: Complete Revascularization Versus Conservative Strategy.	N/A
Completed	`NCT01310309` - EXecutive Registry: Evaluating XIENCE V® in a Multi Vessel Disease	Phase 4
Completed	`NCT00531011` - EXecutive RCT: Evaluating XIENCE V® in a Multi Vessel Disease	Phase 4
Not yet recruiting	`NCT06052670` - Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Coronary Artery Lesions
Completed	`NCT05509296` - Compare the Effectiveness and Safety of Two Different Kinds of Cutting Balloon in Coronary Artery Disease	N/A
Not yet recruiting	`NCT05393882` - Impact of Cholesterol Level on Long-term Coronary Bypass Graft Patency
Active, not recruiting	`NCT01960504` - First in Man Study of the DREAMS 2nd Generation Drug Eluting Absorbable Metal Scaffold (BIOSOLVE-II)	N/A
Completed	`NCT01721096` - XIENCE PRIME Japan Post-Marketing Surveillance (PMS)
Active, not recruiting	`NCT01342822` - Trial to Assess the Everolimus-Eluting Coronary Stent System (PROMUS Element) for Coronary Revascularization	Phase 4
Completed	`NCT01205789` - EXCEL Clinical Trial (Universal Registry)	N/A
Recruiting	`NCT05532605` - Effects of Mindfulness Based Therapy on Illness and Depression in Cardiac Rehab Phase-i	N/A
Completed	`NCT02066623` - Observational Study to Evaluate Short and Long-term Safety of the ABSORB Scaffold
Not yet recruiting	`NCT02946320` - Optimal Predilatation Technique for BVS Implantation	Phase 3
Completed	`NCT01136876` - Kidney Damage in Patients With Moderate Fall in eGFR	Phase 4
Completed	`NCT01249027` - XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval, Single-Arm Study
Terminated	`NCT01136915` - Kidney Damage In Patients With Severe Fall In eGFR	Phase 4