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NCT ID: NCT00416065 Recruiting - Cancer Clinical Trials

PET/CT to Identify "Vulnerable" Arterial Plaque

Start date: April 2004
Phase: N/A
Study type: Interventional

The purpose of this research is to evaluate the presence, location and intensity of FDG uptake in the large arteries using the new technology of fused PET/CT imaging and to compare FDG uptake with the presence of arterial calcifications as seen on the simultaneously acquired CT, in order to determine if FDG was increases incalcified plaque or in a different location in the arterial wall. we will also evaluate the relationship between FDG localization and future cardiovascular events in out patient population

NCT ID: NCT00415636 Completed - Cancer Clinical Trials

Safety and Tolerability of IC83/LY2603618 Administered After Pemetrexed 500 mg/m2 Every 21 Days in Patients With Cancer

Start date: January 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of IC83/LY2603618 for the treatment of cancer.

NCT ID: NCT00414934 Recruiting - Cancer Clinical Trials

18F-NaF PET in Detecting Metastatic Bone Lesion for Patients With Cancer.

Start date: October 2006
Phase: N/A
Study type: Observational

18F ion is a positron emitting bone radiopharmaceuticals. The skeletal uptake of 18F relies on the exchange of hydroxyl ions in the hydroxyapatit crystal which is an indicator of bone metabolic activity (8). It has good soft tissue clearance and high affinity of to the bone matrix. It is able to perform a highly sensitive whole-body screening for bone metastases using a high resolution PET scanner. Therefore, we conduct a prospective study to evaluate the accuracy and clinical value of 18F PET in staging bone metastases by 1. Comparing the sensitivity of 18F-NaF PET with that of 99mTc-MDP scintigraphy; 2. Determining the clinical impact of PET results on subsequent patient management.

NCT ID: NCT00413283 Completed - Cancer Clinical Trials

Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC)

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to identify an effective, well tolerated dose and schedule of romiplostim that is appropriate for the treatment of chemotherapy induced thrombocytopenia (CIT) in patients with non-small cell lung cancer receiving gemcitabine and platinum.

NCT ID: NCT00411450 Completed - Cancer Clinical Trials

Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment

PRECEPT
Start date: November 2006
Phase: Phase 2
Study type: Interventional

The primary objective is to estimate the effect of the human homolog of the Kirsten rat sarcoma-2 virus oncogene (KRAS) mutation status (wild type versus mutant) from tumor tissue on efficacy endpoints in patients with metastatic colorectal cancer (mCRC) receiving second-line chemotherapy with panitumumab after failing first-line treatment.

NCT ID: NCT00409136 Completed - Cancer Clinical Trials

Multi-Center Human Alert Trial to Prevent DVT and PE

Start date: March 2006
Phase: N/A
Study type: Observational

To evaluate physician response to human alerts that inform the clinician that his/her patient may be eligible for thromboprophylaxis. Medical records are reviewed to evaluate prescribing decision and to evaluate rates of venous thromboembolism.

NCT ID: NCT00401063 Completed - Pain Clinical Trials

Usefulness of Acupuncture in Cancer Pain and Quality of Life

Start date: September 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effects of acupuncture on aspects of health including pain, energy level, sleep quality, activities of daily living and appetite.

NCT ID: NCT00400504 Recruiting - Cancer Clinical Trials

Hypercoagulability and Thromboembolic Risk in Patients With Malignant Disease, Evaluated by Thrombelastograph (TEG®)

Start date: November 2006
Phase: N/A
Study type: Observational

Patients with malignancies are at high risk of developing a thromboembolic complication and their treatment with chemo- and or radiation therapy further enhances this risk. Conventional haemostatic tests are not suitable as a screening tool of a hypercoagulable state. A hypercoagulable profile identified with the whole blood Thrombelastograph (TEG) Analyzer parameter maximal amplitude (MA) is reported to correlate with thrombotic events in patients undergoing major non-cardial surgery and recurrent ischemic events in patients undergoing percutaneous coronary intervention. In this study we investigate the correlation between TEG measurements and thromboembolic events in patients with newly diagnosed malignancies. The hypotheses of this study are: 1. Patients with malignancies and hypercoagulability, defined as a TEG MA>69 mm and /or R<4 min is at increased risk of developing thromboembolic complications as compared to those with a MA<69 mm and/or a R>4 min. 2. Hypercoagulability and hence TEG R and MA values are affected by the treatment instituted in these patients (chemo and radiation therapy) rendering the patients more hypercoagulable and hence at increased risk of developing thrombotic complications.

NCT ID: NCT00398840 Terminated - Cancer Clinical Trials

A Study of ARQ 171 in Patients With Advanced Solid Tumors

Start date: November 2006
Phase: Phase 1
Study type: Interventional

This is an open label, dose escalation study of ARQ 171 administered via intravenous infusion (IVI) into a peripheral vein weekly. Patients with advanced solid tumors, who are refractory to available therapy or for whom no standard systemic therapy exists, will be enrolled.

NCT ID: NCT00397930 Completed - Cancer Clinical Trials

Yoga in Treating Sleep Disturbance in Cancer Survivors

YOCAS
Start date: October 2006
Phase: Phase 2
Study type: Interventional

RATIONALE: Yoga may help improve sleep, fatigue, and quality of life in cancer survivors. PURPOSE: This phase II trial is studying how well yoga works in treating sleep disturbance in cancer survivors.