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NCT ID: NCT00041691 Terminated - Clinical trials for Colorectal Neoplasms

Safety Study of 90Y-hMN14 to Treat Colorectal Cancer Patients With Limited Residual Disease After Surgery

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to determine the safety of 90Y-hMN14 at different dose levels in the treatment of residual colorectal cancer following recent surgery.

NCT ID: NCT00044837 Terminated - HIV Infections Clinical Trials

Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to find out if the anti-HIV drugs nelfinavir (NFV), lopinavir/ritonavir (LPV/r), and efavirenz (EFV) change the amount of estrogen in the blood when taken along with hormone replacement therapy (HRT) for menopause. HRT can be helpful for treating bothersome symptoms of menopause. However, it is not routinely used in HIV-infected postmenopausal women because it is not known how HRT interacts with anti-HIV drugs. The information obtained from this study will help doctors make recommendations for HRT in postmenopausal HIV-infected women.

NCT ID: NCT00046436 Terminated - HIV Infections Clinical Trials

Rapid HIV Tests for Women Late in Pregnancy and During Labor

Start date: n/a
Phase: N/A
Study type: Observational

This study will look at how well the OraQuick HIV 1/2 Antibody rapid test works and how women accept being tested for HIV late in pregnancy and during labor. For women with positive test results, the study will look at whether or not these women accept anti-HIV drugs and which drugs they receive.

NCT ID: NCT00048659 Terminated - Prostatic Neoplasms Clinical Trials

YM598 Added to Mitoxantrone/Prednisone to Control Pain in Metastatic Prostate Cancer Patients No Longer Responding to Hormone Therapy

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if patients who take YM598 in addition to mitoxantrone and prednisone (standard therapy) experience improvement in the pain associated with prostate cancer metastases in the bone.

NCT ID: NCT00049959 Terminated - Clinical trials for Basal Cell Carcinoma

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of the two studies is to determine whether an experimental therapy using a photoactive drug, verteporfin, in combination with direct light exposure of basal cell carcinoma of the skin can safely eliminate these skin tumors.

NCT ID: NCT00050297 Terminated - Prostate Cancer Clinical Trials

YM598 in Patients With Rising PSA After Initial Therapy for Localized Prostate Cancer

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the optimal dosage of YM598 for slowing down disease progression in patients with rising PSA after initial therapy for localized prostate cancer.

NCT ID: NCT00051584 Terminated - Ovarian Neoplasms Clinical Trials

Safety/Efficacy Study of SGN-15 (Antibody-Drug Conjugate) Combined With Gemcitabine in Patients With Ovarian Cancer

Start date: n/a
Phase: Phase 2
Study type: Interventional

This is an open-label, randomized phase II trial comparing treatment with a monoclonal antibody (mAb) drug immunoconjugate, SGN-15, administered weekly in combination with weekly Gemzar® (Gemcitabine) to treatment with Gemzar® alone. The primary objectives of this study are to determine the toxicity and safety profile of the combination of SGN-15 and Gemzar®, to estimate the clinical response rate and to estimate the duration of response of this combination therapy administered to patients with advanced ovarian cancer, compared to treatment with Gemzar® alone.

NCT ID: NCT00051766 Terminated - HIV Infections Clinical Trials

Computer-Assisted Adherence Program for Patients Taking Anti-HIV Drugs

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a computer-assisted, self-administered adherence program for patients on complicated anti-HIV drug regimens.

NCT ID: NCT00055432 Terminated - Ovarian Cancer Clinical Trials

Gemzar (Gemcitabine) and Alimta (Pemetrexed) in the Treatment of Patients With Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer

Start date: n/a
Phase: Phase 2
Study type: Interventional

This study hopes to evaluate whether the combination of Gemzar plus Alimta will have any beneficial effects for patients with recurrent platinum-sensitive or platinum-resistant ovarian or peritoneal cancer. Treatments are weekly for two weeks, with the 3rd week off and will be repeated every 21 days. Side effects and the overall safety of the treatment will also be monitored and evaluated. In addition, a Quality of Life questionnaire is part of this study to help measure patient perceived benefits or drawbacks to this treatment regimen.

NCT ID: NCT00060515 Terminated - Clinical trials for Mitochondrial Diseases

RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease

Start date: n/a
Phase: Phase 1
Study type: Interventional

The objective of the study is to determine the safety and tolerability of RG2133 in patients with Mitochondrial Disease.